Evaluation of peanuts as a source of bioactive nutrients for enhancement of endothelial function and cognitive performance. Functional foods represent one of the fastest growing food markets in the world, particularly foods which can offset adverse health conditions. The Partner Organisation, Peanut Company of Australia (PCA), is committed to developing peanut varieties, such as the high oleic peanut, that are nutritionally superior to the traditional varieties. By investing in research PCA aims ....Evaluation of peanuts as a source of bioactive nutrients for enhancement of endothelial function and cognitive performance. Functional foods represent one of the fastest growing food markets in the world, particularly foods which can offset adverse health conditions. The Partner Organisation, Peanut Company of Australia (PCA), is committed to developing peanut varieties, such as the high oleic peanut, that are nutritionally superior to the traditional varieties. By investing in research PCA aims to substantiate the nutritional benefits of these products and position itself in functional foods. Scientific evaluation of the health benefits that can be derived from consuming foods will enhance the national food industry through the growth of domestic and international licensing and export markets, and provide new employment opportunities in both rural and manufacturing sectors.Read moreRead less
Immersive Technologies for Rapid Metallic Tank Inspection and Repairs. Metal tank silos house some of the most dangerous chemicals, which erode the internal structure of the tank over time. It is critical to check the integrity of the tank to prevent disasters from occurring. NDE solutions uses a rapid motion scanner (RMS) to scan the interior surface of the container while it is still full of its storage material. It is the aim of this project to use Augmented Reality, to overlay the scan provi ....Immersive Technologies for Rapid Metallic Tank Inspection and Repairs. Metal tank silos house some of the most dangerous chemicals, which erode the internal structure of the tank over time. It is critical to check the integrity of the tank to prevent disasters from occurring. NDE solutions uses a rapid motion scanner (RMS) to scan the interior surface of the container while it is still full of its storage material. It is the aim of this project to use Augmented Reality, to overlay the scan provided by the RMS, onto the worker's view of the tank, control the robot via. hand gestures, and facilitate remote training/guidance. The result will allow for inspection workers to quickly and accurately the location of critical failures, without performing the hazardous procedures of internal tank inspection. Read moreRead less
Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide t ....Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide targets and/or concepts for the pharmacotherapy of obesity.Read moreRead less
Methodology for assessing the vulnerability of multimodal transport networks and developing remedial measures to safeguard network performance. When transport networks fail, the effects on people and the economy can be devastating. The consequences for Hobart of the 1975 Tasman Bridge collapse provide a prime example. Failure may also result from extreme weather and natural disasters, traffic congestion and incidents, commercial failure, human error, or malevolence (such as sabotage). This proje ....Methodology for assessing the vulnerability of multimodal transport networks and developing remedial measures to safeguard network performance. When transport networks fail, the effects on people and the economy can be devastating. The consequences for Hobart of the 1975 Tasman Bridge collapse provide a prime example. Failure may also result from extreme weather and natural disasters, traffic congestion and incidents, commercial failure, human error, or malevolence (such as sabotage). This project will develop a methodology for auditing a transport network to identify where infrastructure failure will have the worst consequences for movement of people and goods. The research will provide tools for planners to determine critical network locations, and devise strategies and remedial measures to safeguard network performance.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100037
Funder
Australian Research Council
Funding Amount
$170,000.00
Summary
Laser microdissection facility. Laser microdissection facility: Laser microdissection (LMD) is a proven and effective approach to isolate pure cell populations from heterogeneous tissue samples in order to analyse DNA, RNA, and protein content. LMD provides an important advantage to research engaged in basic biological research as it allows for molecular profiling at the cellular level that can not be achieved from whole tissue samples. This project will provide a LMD facility aimed at understan ....Laser microdissection facility. Laser microdissection facility: Laser microdissection (LMD) is a proven and effective approach to isolate pure cell populations from heterogeneous tissue samples in order to analyse DNA, RNA, and protein content. LMD provides an important advantage to research engaged in basic biological research as it allows for molecular profiling at the cellular level that can not be achieved from whole tissue samples. This project will provide a LMD facility aimed at understanding many important biologically cellular mechanisms.Read moreRead less
Bitter Taste As A Mediator Of Food Intake And Postprandial Glycaemia In Health And Type 2 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$735,430.00
Summary
The gut “tastes” contents passing through it in a similar manner to the tongue. Recent evidence suggests that bitter substances in the gut can reduce appetite and slow the emptying of meals from the stomach, by stimulating gastrointestinal hormone release. We propose studies to understand how this system functions in health and type 2 diabetes, and whether it can be targeted to provide new diabetes treatments
Discovery Early Career Researcher Award - Grant ID: DE120101807
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Fat sensing in the oral cavity and gastrointestinal tract: role in the regulation of gastrointestinal function and energy intake in health and obesity. This project will determine whether a reduced capacity to sense, or taste, the presence of fats in the oral cavity and the gastrointestinal tract diminishes the effects of fat on those aspects of gut function that regulate appetite and suppress energy intake. The project will, accordingly, provide important insights into the pathophysiology of ob ....Fat sensing in the oral cavity and gastrointestinal tract: role in the regulation of gastrointestinal function and energy intake in health and obesity. This project will determine whether a reduced capacity to sense, or taste, the presence of fats in the oral cavity and the gastrointestinal tract diminishes the effects of fat on those aspects of gut function that regulate appetite and suppress energy intake. The project will, accordingly, provide important insights into the pathophysiology of obesity.Read moreRead less
Continuous process improvement through workstation feedback for General Practice medicine using experts-in-the-loop data mining. This project investigates the iterative use of data mining results to allow experts to construct feedback to influence subsequent production work. We explore the problem in the context of General Practice medicine by having General Practitioners (GPs) review emerging patterns from their own practice's electronic medical records and author feedback to discourage undesi ....Continuous process improvement through workstation feedback for General Practice medicine using experts-in-the-loop data mining. This project investigates the iterative use of data mining results to allow experts to construct feedback to influence subsequent production work. We explore the problem in the context of General Practice medicine by having General Practitioners (GPs) review emerging patterns from their own practice's electronic medical records and author feedback to discourage undesirable patterns. The work will have immediate applicability to medical practice and will drive innovation in data mining method, notably for efficient identification of temporal and complex niche patterns. More broadly, the work will extend the way data mining is used to create new expectations of workstation behaviour.Read moreRead less
Developing group-based elicitation methods to improve decision making. This project aims to develop an elicitation methodology enabling multiple members of a team to contribute to the same technical problem - enabling expertise to be accurately combined while avoiding group and individual sources of bias. Good elicitation methods minimise bias in estimates and forecasts - which otherwise erode value and lead to sub-optimal decision making. Existing methods, however, ignore group structures; that ....Developing group-based elicitation methods to improve decision making. This project aims to develop an elicitation methodology enabling multiple members of a team to contribute to the same technical problem - enabling expertise to be accurately combined while avoiding group and individual sources of bias. Good elicitation methods minimise bias in estimates and forecasts - which otherwise erode value and lead to sub-optimal decision making. Existing methods, however, ignore group structures; that is that decisions made by, or on, the advice of teams have different characteristics than individual decisions and often preclude the use of methods designed to limit individuals' biases. By encoding the method into a computerised tool the project will assist public and private sector enterprises to improve group decision making.Read moreRead less
Development of a Global Decision Support System towards Virtual Manufacturing. The aim of this research project is to develop a global decision support system (GDSS) in order to assist SMEs to improve their competitiveness in the dynamic global market while providing an industry oriented research training for a high calibre PhD student, who would be a valuable asset to Australia. The GDSS will help SMEs leverage their operations in a global context and to adopt a realistic virtual manufacturing ....Development of a Global Decision Support System towards Virtual Manufacturing. The aim of this research project is to develop a global decision support system (GDSS) in order to assist SMEs to improve their competitiveness in the dynamic global market while providing an industry oriented research training for a high calibre PhD student, who would be a valuable asset to Australia. The GDSS will help SMEs leverage their operations in a global context and to adopt a realistic virtual manufacturing system in the future. The significance of the project includes developing a new methodology and a GDSS to assess virtual manufacturing issues for SMEs and assisting them making timely decisions.Read moreRead less