How do cells survive nutrient stress? Insight into mechanisms. This project studies cell survival under nutrient stress in eukaryotes. Building on extensive preliminary data that identifies novel TOR (Target of Rapamycin) Complex 2 (TORC2) control points it expects to generate new knowledge of critical and conserved features of stress control of macroautophagy that ensures cell survival. It uses interdisciplinary and innovative approaches to validate and characterize nutrient-stress dependent si ....How do cells survive nutrient stress? Insight into mechanisms. This project studies cell survival under nutrient stress in eukaryotes. Building on extensive preliminary data that identifies novel TOR (Target of Rapamycin) Complex 2 (TORC2) control points it expects to generate new knowledge of critical and conserved features of stress control of macroautophagy that ensures cell survival. It uses interdisciplinary and innovative approaches to validate and characterize nutrient-stress dependent signaling. Expected outcomes include novel insights into environmental control of cell proliferation and forging cross institutional collaborations. This knowledge benefits basic and applied biology and is relevant to industries/projects utilizing living cells as nutrient supports cell survival and proliferation.Read moreRead less
Towards 'zero hunger': improving food relief services in Australia. This project aims to improve the effectiveness of the food relief sector in meeting the needs of >5m Australians experiencing food insecurity annually. Following an innovative co-design process with sector stakeholders and their clients, this project investigates food relief service models that satisfy emergency needs as well as address root causes of food insecurity. Expected outcomes include tested best-practice guidelines and ....Towards 'zero hunger': improving food relief services in Australia. This project aims to improve the effectiveness of the food relief sector in meeting the needs of >5m Australians experiencing food insecurity annually. Following an innovative co-design process with sector stakeholders and their clients, this project investigates food relief service models that satisfy emergency needs as well as address root causes of food insecurity. Expected outcomes include tested best-practice guidelines and auditing tools for improving, monitoring and evaluating food relief services. These will not only assist >2,500 volunteer-run organisations to deliver more nutritious foods to more people, through a more dignified, fairer and diversified service, but map a pathway for clients out of food insecurity.Read moreRead less