Dark Matter Discovery. Dark matter research is fundamental breakthrough science, thus its National and Community benefits can only be indirect. This, nevertheless, does not reduce the importance of these benefits. The proposed program strengthens Australian fundamental science by extending it in a new direction, and considerably boosts the quality of theoretical dark matter research in Australia. Since a large part of the proposed work is expected to be performed in international collaboratio ....Dark Matter Discovery. Dark matter research is fundamental breakthrough science, thus its National and Community benefits can only be indirect. This, nevertheless, does not reduce the importance of these benefits. The proposed program strengthens Australian fundamental science by extending it in a new direction, and considerably boosts the quality of theoretical dark matter research in Australia. Since a large part of the proposed work is expected to be performed in international collaboration, positive results will increase the Australian presence on the international astro-particle physics scene. Successful students involved in this project are also expected to assume leading roles in international dark matter research.Read moreRead less
Origins of our Universe. The present proposal will study the origins of our Universe, which is one of the grand challenges of 21st century physics. As such it will utilise insights and discoveries in many areas of physics, ranging from string theory and particle physics at the highest energies, to x-ray, optical and radio astronomy. The research program will add to our understanding of a fundamental branch of science - extending it in new directions - thereby considerably boosting the quality of ....Origins of our Universe. The present proposal will study the origins of our Universe, which is one of the grand challenges of 21st century physics. As such it will utilise insights and discoveries in many areas of physics, ranging from string theory and particle physics at the highest energies, to x-ray, optical and radio astronomy. The research program will add to our understanding of a fundamental branch of science - extending it in new directions - thereby considerably boosting the quality of cosmology and theoretical physics research in Australia. In concert with our international collaborations, work arising from this fellowship will enhance the Australian presence on the international cosmology, astro-particle, and theoretical physics scene.
Read moreRead less
Molecular genetic analyses of trinucleotide repeat expansions. Several neuronal diseases like Huntington's disease, Frederick's ataxia and fragile X syndrome are caused by expansion of trinucleotide repeat sequences in the deoxyribonucleic acid (DNA). These diseases show progressive severity in subsequent generations. Here we use a simple plant model with a very similar DNA mutation to study the genetic basis of repeat expansions over several generations across populations. This proposal will im ....Molecular genetic analyses of trinucleotide repeat expansions. Several neuronal diseases like Huntington's disease, Frederick's ataxia and fragile X syndrome are caused by expansion of trinucleotide repeat sequences in the deoxyribonucleic acid (DNA). These diseases show progressive severity in subsequent generations. Here we use a simple plant model with a very similar DNA mutation to study the genetic basis of repeat expansions over several generations across populations. This proposal will improve our mechanistic understanding of genetic diseases in populations. In addition, this proposal is expected to lead to identification of potential targets and technologies that would be of interest to Australian industry.Read moreRead less