Functionalised MMP Inhibitors as Radiodiagnostic, Radiotherapeutic, and Radiation-Sensitising Agents for Metastatic Cancer. Identifying and treating malignant cancers is one of the major challenges facing the scientific and medical communities. In order to minimise side effects that accompany most treatments of cancer it is necessary to find ways of targeting the therapy to tumours and away from healthy organs. A difference between tumours and healthy tissues is the amount of the proteins (calle ....Functionalised MMP Inhibitors as Radiodiagnostic, Radiotherapeutic, and Radiation-Sensitising Agents for Metastatic Cancer. Identifying and treating malignant cancers is one of the major challenges facing the scientific and medical communities. In order to minimise side effects that accompany most treatments of cancer it is necessary to find ways of targeting the therapy to tumours and away from healthy organs. A difference between tumours and healthy tissues is the amount of the proteins (called MMPs) that tumours use to break out of their surroundings, to break into and out of the blood system, and to establish new colonies of cancer cells or metastases. This difference also distinguishes the most aggressive cancers. The purpose of this project is to develop means of identifying and targeting cancers using molecules that bind to these MMP proteins.Read moreRead less
Superfluid helium nanodroplet spectroscopy. Molecules trapped in a helium nanodroplet find themselves in an ultracold liquid environment from which they cannot escape. As such, the molecules are forced to interact and this is studied at a resolution that is unrivaled in condensed phase spectroscopy. This technique will be used to create new materials and study the dynamics behind a large range of chemical processes. The results are expected to lead to a greater understanding of condensed phase c ....Superfluid helium nanodroplet spectroscopy. Molecules trapped in a helium nanodroplet find themselves in an ultracold liquid environment from which they cannot escape. As such, the molecules are forced to interact and this is studied at a resolution that is unrivaled in condensed phase spectroscopy. This technique will be used to create new materials and study the dynamics behind a large range of chemical processes. The results are expected to lead to a greater understanding of condensed phase chemistry and chemical reactions in general.Read moreRead less