Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453521
Funder
Australian Research Council
Funding Amount
$508,374.00
Summary
National Heavy Ion Accelerator. The principal objectives are to develop a facility to provide energetic heavy ions for basic science, applications and research training. This will be accomplished through an enhancement of a superconducting linear accelerator using innovative technology, and extension of the available beam species through improvements to a large electrostatic tandem accelerator. The facility provides research resources for a broad range of national and international users.
ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the ....ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the whole genome as large inserts in BAC vectors, and build a "golden path" with minimal overlap. We will construct libraries of expressed genes from tammar tissues and array them for use in analysing gene expression.Read moreRead less
Genomic Analysis Of DNA Binding And Gene Regulation By The Chromatin Remodelling Factor UBF
Funder
National Health and Medical Research Council
Funding Amount
$624,254.00
Summary
Synthesis of ribosomes, the cellular protein synthetic machinery, is the major anabolic event of a growing cell and is frequently dysregulated during disease such as cancer. This grant will examine a protein termed UBF that we think plays an important role in orchestrating the cellular response to dysregulated ribosome biogenesis. By understanding how UBF functions we hope to uncover novel therapeutic approaches to treat diseases associated with ribosome stress .
Regulation Of Ribosomal RNA Gene Chromatin During Malignant Transformation.
Funder
National Health and Medical Research Council
Funding Amount
$882,486.00
Summary
The overarching goal of this proposal is to determine the molecular basis for tumour cell dependence on activated ribosomal RNA gene repeats (rDNA). Our working model posits that rDNA repeats become activated through changes in rDNA chromatin structure that include increased binding of the RNA Polymerase I transcription factor UBF.
Mental health, job quality and workforce participation: evidence from population health research to address complex problems and conflicting policies. Mental disorders such as depression are a major cause of disability. Improving mental health can increase productivity and workforce participation. However, the psychosocial quality of work is a factor that overlays the relationship between work and health. Poor quality work (for example, unreasonable time pressure, insecurity) increases the risk ....Mental health, job quality and workforce participation: evidence from population health research to address complex problems and conflicting policies. Mental disorders such as depression are a major cause of disability. Improving mental health can increase productivity and workforce participation. However, the psychosocial quality of work is a factor that overlays the relationship between work and health. Poor quality work (for example, unreasonable time pressure, insecurity) increases the risk of poor mental health, absenteeism, and exit from the workforce. This project will analyse data following people over time to investigate the long-term health and employment consequences of poor psychosocial job quality, and consider the special case of mature age workers. It will identify those individuals at greatest risk, and factors that can buffer against the adverse effects of poor quality work.Read moreRead less
Working longer, staying healthy and keeping productive. Working longer, staying healthy and keeping productive. This project aims to develop a policy suite to respond to an older workforce. By 2060, nearly half of Australians aged 64 or older will be employed. Failure to address their health problems could threaten Australia’s economy, tax base and provision of health and care services. This collaboration between national policy portfolios (employment, social services, workplace health and socia ....Working longer, staying healthy and keeping productive. Working longer, staying healthy and keeping productive. This project aims to develop a policy suite to respond to an older workforce. By 2060, nearly half of Australians aged 64 or older will be employed. Failure to address their health problems could threaten Australia’s economy, tax base and provision of health and care services. This collaboration between national policy portfolios (employment, social services, workplace health and social equity) and expert scientists in work, health, social equality and policy process intends to reveal the diversity of older workers’ work-health dilemmas and effective ways for national policies to solve them. The policy suite will promote financial independence and meet social goals of equity and healthy ageing.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560959
Funder
Australian Research Council
Funding Amount
$165,000.00
Summary
The Macquarie National Low Temperature Optoelectronic Thin Film Growth Facility. Funding is requested for an Australian facility for the growth of nitride and oxide thin films with in-situ optical analysis equipment for the monitoring of growth parameters. It is envisaged that this facility would be for the development of materials and device structures for photonic, electronic and optoelectronic applications. The facility will also provide a leading Australian source of these materials for fund ....The Macquarie National Low Temperature Optoelectronic Thin Film Growth Facility. Funding is requested for an Australian facility for the growth of nitride and oxide thin films with in-situ optical analysis equipment for the monitoring of growth parameters. It is envisaged that this facility would be for the development of materials and device structures for photonic, electronic and optoelectronic applications. The facility will also provide a leading Australian source of these materials for fundamental material studies utilising nuclear analysis and implantation technologies, high resolution X-ray diffraction, high spatial resolution micro-cathodoluminescence and other forms of analysis. Ex-situ optical analysis equipment is also requested for post-growth evaluation to compliment and evaluate the in-situ analysis.Read moreRead less
Tackling the Tough Problems in Productivity Measurement: Infrastructure, Services and R&D. Productivity is seen as a main driver of economic growth and welfare improvements. Productivity indexes are used in a variety of policy contexts, in particular in determining the effectiveness (or otherwise) of government policies. Most industrialized countries have productivity accounts, but measurement problems persist and may even be more problematic in the future given an expansion in new goods and ser ....Tackling the Tough Problems in Productivity Measurement: Infrastructure, Services and R&D. Productivity is seen as a main driver of economic growth and welfare improvements. Productivity indexes are used in a variety of policy contexts, in particular in determining the effectiveness (or otherwise) of government policies. Most industrialized countries have productivity accounts, but measurement problems persist and may even be more problematic in the future given an expansion in new goods and services. Improved productivity measurement and an improved understanding of its sources can inform aggregate and regional policy. The project includes collaboration with the Australian Bureau of Statistics and the Productivity Commission, with the participation of the Reserve Bank of Australia.Read moreRead less
Special Research Initiatives - Grant ID: SR0354852
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Sustainable Regions for a Competitive Australia. How can metropolitan, rural and remote regions balance economic and job growth, with environmental and social sustainability? This Initiative establishes a Network of researchers to work collaboratively on questions of environmental best practice, community development, regional governance, labour markets, economic development and technology transfer. The Network's vision is to find ways to use existing and future research to help make Australia ....Sustainable Regions for a Competitive Australia. How can metropolitan, rural and remote regions balance economic and job growth, with environmental and social sustainability? This Initiative establishes a Network of researchers to work collaboratively on questions of environmental best practice, community development, regional governance, labour markets, economic development and technology transfer. The Network's vision is to find ways to use existing and future research to help make Australia's regions more competitive on world markets and more environmentally sustainable, and to help build stronger regional communities. The Network cuts across traditional discipline boundaries to find integrated solutions to the real problems confronting Australian regions.Read moreRead less
Belonging and sexual citizenship among gender and sexual minority youth. In the context of well-documented threats to the mental health and well-being of minority young people, this project will examine the experiences of two different generations of gender and sexual minority youth growing up in Australia, and the sources of support they have found most useful. Innovative contextual analysis will involve documentary and archival research alongside individual and group interviews. Through a focu ....Belonging and sexual citizenship among gender and sexual minority youth. In the context of well-documented threats to the mental health and well-being of minority young people, this project will examine the experiences of two different generations of gender and sexual minority youth growing up in Australia, and the sources of support they have found most useful. Innovative contextual analysis will involve documentary and archival research alongside individual and group interviews. Through a focus on the promotion of well-being and participatory citizenship in a rapidly changing social world, the findings aim to contribute new theory concerning transitions from youth to adulthood, improved methodology for the study of marginal and sometimes hard-to-reach populations, and better quality policy and practice.Read moreRead less