BioPolymer Fibres For Remodelling Mdx And Damaged Muscle
Funder
National Health and Medical Research Council
Funding Amount
$527,286.00
Summary
This project aims to generate new, smart polymers for use in re-building muscle that has degenerated due to disease and-or trauma damage. The merger of smart polymers with biologically based solutions and cells has great potential to improve outcomes of treatments of damaged muscle in diseases such as Muscular Dystrophy.
The Use Of Nitric Oxide To Control Infections By Biofilm Forming Bacteria
Funder
National Health and Medical Research Council
Funding Amount
$551,767.00
Summary
80% of infections are the result of bacteria growing as a biofilm. It can require up to 1000x's the normal antibiotic concentration to kill a biofilm. When the bacteria disperse from the biofilm, they become antibiotic sensitive again. Our team has identified a strategy that controls biofilm dispersal. This project will design and test novel compounds that disperse biofilms so that they can be killed by the host immune response or by antibiotic treatment.