Methylation Sensitive Genes And The Transition To Allergic Disease: A Twin Study
Funder
National Health and Medical Research Council
Funding Amount
$493,843.00
Summary
Australia has amongst the highest reported prevalence allergic conditions (including asthma) in the world. Despite this, little is known about how these conditions arise. Mounting evidence implicates environmentally induced disruption of the genetic blueprint via a process known as epigenetics. We are combining the strengths of a unique collection of identical twins where one of a pair is sensitive to house dust mite, with cutting edge genomics, to characterise the pathways leading to allergy in ....Australia has amongst the highest reported prevalence allergic conditions (including asthma) in the world. Despite this, little is known about how these conditions arise. Mounting evidence implicates environmentally induced disruption of the genetic blueprint via a process known as epigenetics. We are combining the strengths of a unique collection of identical twins where one of a pair is sensitive to house dust mite, with cutting edge genomics, to characterise the pathways leading to allergy in children.Read moreRead less
The Effects Of Oxytocin Nasal Spray On Mechanisms Of Social-communication In Young People With Autism
Funder
National Health and Medical Research Council
Funding Amount
$191,400.00
Summary
Autism is charcterised by deficits in social behaviour and communication, and is a cause of major lifelong disability. A novel intervention, Oxytocin, enhances social communication in non-clinical populations. This project will determine whether OT improves social communication deficits characteristic of autism. This project is a critical first step towards treating a core deficit of autism.