Improved theory and practice in econometric modelling of nonlinear spatial time series. Modern Australia faces many challenges in economic and global climate changes, which require advanced statistical technologies in modeling and forecasting of econometric spatial time series data. This project will provide flexible models and methods that enable practitioners to more accurately measure and manage economic and climatic risks.
Improving Care Of The Dying With Chronic Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$130,000.00
Summary
Chronic heart failure is increasing in prevalence and is primarily a condition of ageing. Although chronic heart failure has worse outcomes than many cancers, patients are often denied the benefits of palliative care with its emphasis on symptom management, spirituality, emotional health and focus on family issues. This project seeks to assess the state of knowledge in Australia related to palliative care in chronic heart failure. Guidelines and care maps appropriate to Australian conditions wil ....Chronic heart failure is increasing in prevalence and is primarily a condition of ageing. Although chronic heart failure has worse outcomes than many cancers, patients are often denied the benefits of palliative care with its emphasis on symptom management, spirituality, emotional health and focus on family issues. This project seeks to assess the state of knowledge in Australia related to palliative care in chronic heart failure. Guidelines and care maps appropriate to Australian conditions will be developed and their usefulness assessed in improving care of patients and their families.Read moreRead less
Three-dimensional magnetotelluric imaging of lithospheric-scale mineral systems from source to deposit. Geochemical studies indicate that world-class mineral deposits are partly sourced from fluids emerging from Earth's mantle and lower crust. Finding major mineral deposits in the future will therefore require knowledge of which parts of the crust and mantle yield the most prospective locations. However, there are few methods that can image deep Earth resources, and these can be very expensive ....Three-dimensional magnetotelluric imaging of lithospheric-scale mineral systems from source to deposit. Geochemical studies indicate that world-class mineral deposits are partly sourced from fluids emerging from Earth's mantle and lower crust. Finding major mineral deposits in the future will therefore require knowledge of which parts of the crust and mantle yield the most prospective locations. However, there are few methods that can image deep Earth resources, and these can be very expensive. We propose to develop the magnetotelluric method as a low-cost and rapid approach for delineating 3D information on deep mineral systems beneath existing major deposits, and adapting this to explore in greenfield locations.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668155
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Instrumentation for combined seismic and electromagnetic Earth sounding. The set of geophysical recorders will provide the means to enhance understanding of the structure of the Australian continent in 3-D. The interpretation of multiple images of Earth structure will help to link features in the crust and mantle beneath, and provide controls on the evolution and assembly of the present continent, with a major contribution to possible geotransects as recommended in the 2003 National Strategic Pl ....Instrumentation for combined seismic and electromagnetic Earth sounding. The set of geophysical recorders will provide the means to enhance understanding of the structure of the Australian continent in 3-D. The interpretation of multiple images of Earth structure will help to link features in the crust and mantle beneath, and provide controls on the evolution and assembly of the present continent, with a major contribution to possible geotransects as recommended in the 2003 National Strategic Plan for the Geosciences. Combining seismic and electromagnetic methods will provide both geochemeical and geophysical constaints, e.g., on zones of alteration and shear with the potential for deep mineralisation. Read moreRead less
Targeting RCAN1 To Treat Type 2 Diabetes And Obesity
Funder
National Health and Medical Research Council
Funding Amount
$814,468.00
Summary
Obesity and impaired insulin secretion are significant contributors to Type 2 diabetes. In this project we demonstrate that a protein called RCAN1 contributes to both fat mass and insulin secretion and that this contribution is exacerbated in obesity and in Type 2 diabetes. We will identify how RCAN1 controls these major metabolic pathways with outcomes including the development of new therapeutics for obesity and Type 2 diabetes.
Bitter Taste As A Mediator Of Food Intake And Postprandial Glycaemia In Health And Type 2 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$735,430.00
Summary
The gut “tastes” contents passing through it in a similar manner to the tongue. Recent evidence suggests that bitter substances in the gut can reduce appetite and slow the emptying of meals from the stomach, by stimulating gastrointestinal hormone release. We propose studies to understand how this system functions in health and type 2 diabetes, and whether it can be targeted to provide new diabetes treatments
Physical and Chemical Constraints of Fluid Activated Processes During the Polyphase Tectonic Evolution of the Olary Domain, S.A. The Olary Domain, eastern South Australia, underwent several phases of deformation and metamorphism. These events mobilised fluids leading, amongst other features, to the formation of breccia bodies and mineral deposits. The complex nature of the geological evolution of the region obscures relationships of fluid migration to the structural history. Fluid inclusion stud ....Physical and Chemical Constraints of Fluid Activated Processes During the Polyphase Tectonic Evolution of the Olary Domain, S.A. The Olary Domain, eastern South Australia, underwent several phases of deformation and metamorphism. These events mobilised fluids leading, amongst other features, to the formation of breccia bodies and mineral deposits. The complex nature of the geological evolution of the region obscures relationships of fluid migration to the structural history. Fluid inclusion studies and stable isotope analyses combined with structural analyses on micro to macro scales shall establish links between the thermal and structural evolution of the area. This will provide insigth into the scale and physico-chemical characteristics of fluids and mineralising processes an relate these to the tectono-thermal history.Read moreRead less
Aiding the Search for Diamonds in South Australia: Source and origin of Mesozoic kimberlite dyke swarms and their mantle samples. Because of significant, yet tantalising, alluvial diamond discoveries in the Adelaide Hills and Flinders Ranges over more than 100 years, South Australia can be viewed to have considerable potential as a diamond producer. Yet this potential is unresolved because little is known about the occurrence and diamond content of the kimberlite source rocks that have carried t ....Aiding the Search for Diamonds in South Australia: Source and origin of Mesozoic kimberlite dyke swarms and their mantle samples. Because of significant, yet tantalising, alluvial diamond discoveries in the Adelaide Hills and Flinders Ranges over more than 100 years, South Australia can be viewed to have considerable potential as a diamond producer. Yet this potential is unresolved because little is known about the occurrence and diamond content of the kimberlite source rocks that have carried the diamonds to the near surface and shed them into the weathering environment. This collaborative research project will use new uncommonly available samples provided by commercial diamond exploration to determine the structure , geochemistry and history of the mantle that underlies the Flinders Ranges and Adelaide Hills at depths between 40 and 250km.Read moreRead less
The Genesis and Tectonic Setting of Iron Oxide Associated Mineralisation in Germany and South Australia. FeOx associated mineralisations are not restricted to Olympic Dam and Ernest Henry types but occur in various geological settings, e.g. the Mt Painter and Olary region, S A. Ocurrences in Central Europe (Erzgebirge, Harz/Calvörde) contain U and other metals, their structural setting is well recorded. Together with the Bergakademie Freiberg, Germany, and the University of Nancy, France, these ....The Genesis and Tectonic Setting of Iron Oxide Associated Mineralisation in Germany and South Australia. FeOx associated mineralisations are not restricted to Olympic Dam and Ernest Henry types but occur in various geological settings, e.g. the Mt Painter and Olary region, S A. Ocurrences in Central Europe (Erzgebirge, Harz/Calvörde) contain U and other metals, their structural setting is well recorded. Together with the Bergakademie Freiberg, Germany, and the University of Nancy, France, these mineralisations shall be investigated with modern geological and geochemical methods to develop a unifying model for the genesis of iron oxide associated U-metal-REE deposits. This will help identifying exploration targets and distinguish different types of mineralisation upon their genetic setting.Read moreRead less
Mobility of metals in hydrothermal solutions: critical experiments and numerical modelling tools to improve exploration success and ore processing. After more than 100 years of intense prospecting, ore deposits with a surface expression or a characteristic geophysical signature have been discovered. As a result, the industry needs innovative and quantitative exploration techniques. Geochemical exploration suffers from a growing gap between ever more powerful geochemical analytical capabilities a ....Mobility of metals in hydrothermal solutions: critical experiments and numerical modelling tools to improve exploration success and ore processing. After more than 100 years of intense prospecting, ore deposits with a surface expression or a characteristic geophysical signature have been discovered. As a result, the industry needs innovative and quantitative exploration techniques. Geochemical exploration suffers from a growing gap between ever more powerful geochemical analytical capabilities and the poor understanding of fundamental processes in hydrothermal systems. By combining new experiments on important geochemical systems (association between the trace elements Te and As with Au) with advances in numerical modelling of H2O-CO2-NaCl fluids, the project aims to bring geochemical exploration in line with geophysical exploration.Read moreRead less