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Practice- And Policy-relevant Research In Skin Cancer Epidemiology, Prevention And Screening
Funder
National Health and Medical Research Council
Funding Amount
$483,402.00
Summary
This Fellowship will enable me to lead an internationally-competitive program of research in skin cancer epidemiology, prevention & screening that will lead to improved patient and population health through impacts on clinical practice and health policy. My aim is to lead paradigm-shifting contributions in: ? Genetic epidemiology of melanoma, ? Precision skin cancer prevention & screening, and ? Public health genomics for cancer prevention.
Statistical Bioinformatics For Network Based Prognostic And Precision Therapy In Complex Disease
Funder
National Health and Medical Research Council
Funding Amount
$463,652.00
Summary
The project aims are to develop bioinformatics solutions that deliver more accurate assessment of prognosis of disease and better prediction of response to drug therapy. This will encourage the translation of research outcomes into practice and lead to increase in Australia’s capacity for research in bioinformatics as well as health and medical research.
Modulating Skin Regenerative Responses To Improve Wound Repair And Fight Carcinogenesis
Funder
National Health and Medical Research Council
Funding Amount
$470,144.00
Summary
Skin disorders, such as hard to heal wounds or the most common skin cancers, are a major burden on the national health system. Despite their different nature they employ similar mechanisms of response to injury. In this project we intend to develop a comprehensive understanding of the genetic and molecular mechanisms at play to allow clinical interventions to prevent or to cure these disorders.
Integrating Behaviour Change And Technology Uptake Models Into Skin Cancer Prevention And Early Detection
Funder
National Health and Medical Research Council
Funding Amount
$459,271.00
Summary
Two in three Australians will develop skin cancer in their lifetime, and skin cancer incidence is expected to increase. Therefore optimal ways to prevent and early detect skin cancers are of utmost importance to Australia’s public. By integrating the latest behaviour change models and technology uptake models to develop innovative interventions, this fellowship aims to ascertain that all Australians regardless of their location have access to optimal skin cancer prevention and early detection ca ....Two in three Australians will develop skin cancer in their lifetime, and skin cancer incidence is expected to increase. Therefore optimal ways to prevent and early detect skin cancers are of utmost importance to Australia’s public. By integrating the latest behaviour change models and technology uptake models to develop innovative interventions, this fellowship aims to ascertain that all Australians regardless of their location have access to optimal skin cancer prevention and early detection care.Read moreRead less
Using Epidemiological Methods To Investigate How Genetic, Environmental And Lifestyle Factors Influence Cancer Incidence And Cancer Survivorship; And Translation Into Cancer Prevention And Policy Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
This research program focuses on investigating genetic, environmental and lifestyle causes of cancer, preventing new cases of cancer, and improving outcomes after a cancer diagnosis, particularly for melanoma and gynaecological cancer, which carry a heavy burden in the Australian population. The research will also inform the best allocation of health system resources for cancer control, and ensure translation of research findings into cancer prevention, clinical practice and policy outcomes.
Towards Precision Medicine For Non-small Cell Lung Cancer
Funder
National Health and Medical Research Council
Funding Amount
$463,652.00
Summary
Better outcomes are needed for lung cancer, a disease that accounts for more cancer-related deaths than any other cancer in Australia or worldwide. My goals are to 1) develop and evaluate in clinical trials targeted therapies and immunotherapies and 2) identify clinically relevant blood and tissue based biomarkers for lung cancer patients. This combination of clinical and translational research will change practice and improve outcomes by delivering precision medicine for lung cancer patients.
Statistical Methods For Identifying Genes Involved In Common Complex Disease
Funder
National Health and Medical Research Council
Funding Amount
$307,232.00
Summary
Better understanding of the genetic component of common diseases (e.g. melanoma, psychiatric disorders) is likely to lead to improved public health. Identification of disease susceptibility loci is currently one of the primary means for increasing our understanding of the biochemical and developmental pathways involved in many common diseases. This application will focus on developing new statistical genetic methods to better understand genetic variation and to allow more effective gene mapping.
Melanoma is a devastating disease. We are investigating new ways to treat and cure this form of cancer. Specifically, we are identifying how the body’s immune system interacts with melanoma and exploring new ways to use one’s own immune cells to destroy the cancer. This is achieved by understanding the interplay between various immune cells during melanoma and current therapies. This knowledge allows us to manipulate the immune cells providing better treatment.