Ecological significance of coral disease on the Great Barrier Reef. Coral disease has contributed significantly to the accelerating deterioration of coral reefs globally, but its impact on the Great Barrier Reef is unknown. This project will determine the prevalence of coral disease on the GBR and evaluate the potential threat it poses to reef health. It will build Australian capacity in the ecology and pathology of coral disease, an emergent global research priority, and provide an important ....Ecological significance of coral disease on the Great Barrier Reef. Coral disease has contributed significantly to the accelerating deterioration of coral reefs globally, but its impact on the Great Barrier Reef is unknown. This project will determine the prevalence of coral disease on the GBR and evaluate the potential threat it poses to reef health. It will build Australian capacity in the ecology and pathology of coral disease, an emergent global research priority, and provide an important benchmark for determining whether disease incidence is increasing. It will provide insights into potential links between environmental / anthropogenic stressors and disease incidence, and identify potential threats to coral reef health.Read moreRead less
Chemical Defenses Against Microbial Colonisation of Living Marine Surfaces. Microorganisms have a major impact on all ecosystems. Many of these effects are due to the formation of biofilms - cell clusters and their slime matrix - on living and non-living surfaces. Biofilm formation is often regulated by chemical signals. The aim of this project is to understand how naturally produced chemical signals mediate the formation of biofilms on surfaces of marine macroalgae (seaweeds) at both the eco ....Chemical Defenses Against Microbial Colonisation of Living Marine Surfaces. Microorganisms have a major impact on all ecosystems. Many of these effects are due to the formation of biofilms - cell clusters and their slime matrix - on living and non-living surfaces. Biofilm formation is often regulated by chemical signals. The aim of this project is to understand how naturally produced chemical signals mediate the formation of biofilms on surfaces of marine macroalgae (seaweeds) at both the ecological and molecular levels. By understanding colonisation of natural living surfaces, this project will lead directly to significant advances in control of microorganisms in a variety of applied areas (water treatment, biomaterials, antifouling).Read moreRead less
Diatom frustules: nanostructures at the base of ocean food webs. Molecules interacting with surfaces are fundamental to biological, chemical and physical processes, including desalinization membrane design, lab-on-a-chip systems, industrial catalysis, bioremediation, neurophysiology and uptake of nutrients for incorporation into food webs. Here, we use diatoms as models for molecule-surface interactions to find basic principles that underlay all of these interactions. This research will train st ....Diatom frustules: nanostructures at the base of ocean food webs. Molecules interacting with surfaces are fundamental to biological, chemical and physical processes, including desalinization membrane design, lab-on-a-chip systems, industrial catalysis, bioremediation, neurophysiology and uptake of nutrients for incorporation into food webs. Here, we use diatoms as models for molecule-surface interactions to find basic principles that underlay all of these interactions. This research will train students and scientists and establish collaborations with leading international scientists in the field.Read moreRead less
Physical and Ecological Structure at the Base of Ocean Food Webs. The coastal ocean is a crucial resource to Australia. In founding a research area on coastal food web function we provide international scientific leadership, train scientists in a cutting edge area, and lay the foundation for improved management of fisheries, aquaculture and species invasions. This work boosts Australia's participation in the International Polar Year, and knowledge about Antarctic Territorial waters. Infrastructu ....Physical and Ecological Structure at the Base of Ocean Food Webs. The coastal ocean is a crucial resource to Australia. In founding a research area on coastal food web function we provide international scientific leadership, train scientists in a cutting edge area, and lay the foundation for improved management of fisheries, aquaculture and species invasions. This work boosts Australia's participation in the International Polar Year, and knowledge about Antarctic Territorial waters. Infrastructure benefit comes from the French government paying for an outstanding French scientist to come to Australia 6 months/yr for 5 yrs. This grant acts as the base for larger projects that import EU and American funds.Read moreRead less
Ecology, physiology and molecular microbiology of coral disease on the Great Barrier Reef. Ecological, physiological, molecular and micro-biological techniques will be used to examine the disease of corals of the Great Barrier Reef (GBR). Molecular techniques include the development of diagnostic techniques for disease identification, using Fluorescent In Situ hybridisation (FISH) and DNA microarrays (CHIPS); physiological experiments include examining the effects of temperature and sediment o ....Ecology, physiology and molecular microbiology of coral disease on the Great Barrier Reef. Ecological, physiological, molecular and micro-biological techniques will be used to examine the disease of corals of the Great Barrier Reef (GBR). Molecular techniques include the development of diagnostic techniques for disease identification, using Fluorescent In Situ hybridisation (FISH) and DNA microarrays (CHIPS); physiological experiments include examining the effects of temperature and sediment on virulence and host susceptibility to disease infection; ecological surveys will examine the extent and seasonality of disease in northern and southern parts of the GBR and on isolated reefs in the central GBR. Management implications of the current coral-disease status of the GBR will be targeted.Read moreRead less
A microscopic and analytical study of extreme thermophile bacteria in simulated environments compared to organic matter in early Earth hydrothermal systems. The study will examine microbial cells and organic residues of cultured thermophilic archaea from simulated extreme environments in terms of temperature, pressure and mineral concentrations. These will be compared, applying observational and geochemical techniques to organic material in geologically earliest ecosystems. A novel approach will ....A microscopic and analytical study of extreme thermophile bacteria in simulated environments compared to organic matter in early Earth hydrothermal systems. The study will examine microbial cells and organic residues of cultured thermophilic archaea from simulated extreme environments in terms of temperature, pressure and mineral concentrations. These will be compared, applying observational and geochemical techniques to organic material in geologically earliest ecosystems. A novel approach will be adopted, of 'backtracking' changes occurring to cultured microbial cells towards their breakdown and disintegration (in contrast to the more common approach of simulating synthesis of organic compounds as a starting point towards structured functioning organisms), and their viability limits. The results of the study will be tested within the currently available theoretical models for the origin of life.Read moreRead less
Understanding evolution of dominant bacteria inhabiting the rodent gut . The gut microbiome is central to animal health and immune function, however we have an incomplete understanding of how this important symbiotic ecosystem evolved. By approaching this knowledge gap from a historical perspective and using real-time observation, this project will address how the gut community evolved with the rodent host and how members of that community respond to new selective pressures. The significance of ....Understanding evolution of dominant bacteria inhabiting the rodent gut . The gut microbiome is central to animal health and immune function, however we have an incomplete understanding of how this important symbiotic ecosystem evolved. By approaching this knowledge gap from a historical perspective and using real-time observation, this project will address how the gut community evolved with the rodent host and how members of that community respond to new selective pressures. The significance of these findings is in their capacity to inform our understanding of the relationship between host and microbe, not only within a key model system, but by extrapolation to other host-microbe systems. Read moreRead less
The costs and consequences of resistance to stress in microbial systems. The coexistence of antibiotic resistant and sensitive bacteria in microbial communities represents a paradox. Combining novel ecological models and competition experiments, this project aims to investigate how the pulsing of antibiotics and resources affects the coexistence of resistant and sensitive bacteria. This project expects to generate new knowledge into how the complex non-equilibrium dynamics of natural systems fee ....The costs and consequences of resistance to stress in microbial systems. The coexistence of antibiotic resistant and sensitive bacteria in microbial communities represents a paradox. Combining novel ecological models and competition experiments, this project aims to investigate how the pulsing of antibiotics and resources affects the coexistence of resistant and sensitive bacteria. This project expects to generate new knowledge into how the complex non-equilibrium dynamics of natural systems feeds back to regulate the spread of antibiotic resistance in microbial communities. This should advance our fundamental understanding of microbial competition, and provide a foundation for the development of new ecologically-aware strategies for managing resistance.Read moreRead less
Targeted isolation of specific marine bacterial species associated with higher organsims for the purpose of discovering new antimicrobial compounds. Specific bacterial species that are commonly found in association with marine plants and animals often produce active secondary metabolites. The aim of this project is to apply our understanding of these bacterial-host associations to the targeted isolation of novel antimicrobials from the marine environment. While these new compounds will undoubted ....Targeted isolation of specific marine bacterial species associated with higher organsims for the purpose of discovering new antimicrobial compounds. Specific bacterial species that are commonly found in association with marine plants and animals often produce active secondary metabolites. The aim of this project is to apply our understanding of these bacterial-host associations to the targeted isolation of novel antimicrobials from the marine environment. While these new compounds will undoubtedly have a number of commercial applications this project focuses on the development of products for dental hygiene in animals. Generally, the urgent need for new antimicrobial compounds to combat the growing number of microbes that are resistant to current antibiotics highlights the importance of this project.Read moreRead less
Future climate change: consequences for decomposition and pathways of carbon flow through rhizosphere fungal communities. The proposed collaboration will provide novel insights into likely consequences of global climate change on decomposition and pathways of carbon flow through forest soils. This will refine predictive models of future climate change and its impacts on the sustainability of Australia's forests. It will also enhance the protection of our valued habitats and their important soil ....Future climate change: consequences for decomposition and pathways of carbon flow through rhizosphere fungal communities. The proposed collaboration will provide novel insights into likely consequences of global climate change on decomposition and pathways of carbon flow through forest soils. This will refine predictive models of future climate change and its impacts on the sustainability of Australia's forests. It will also enhance the protection of our valued habitats and their important soil biodiversity. The knowledge gained will help land managers to adapt current practices to meet the demands of future climate change. This will maximize the opportunities for sequestering carbon in Australia's forests and so contribute to meeting Australia's global responsibility for mitigation of climate change.Read moreRead less