Creating Stem Cell Niches To Repair The Nigrostriatal System
Funder
National Health and Medical Research Council
Funding Amount
$837,033.00
Summary
It has been difficult to treat Parkinson's with stem cells because transplants make to few new cells and form tumors. In other organs, specialized locations called niches regulate the division and maturation of stem cells. By making a niche in the brains of animals with experimental parkinsonism we induced the brain to make new nerve cells and repair the parkinsonism. This is important because it shows how to use cell based therapies to treat neurodegenerative disorders. .