Enhancing Hypnotic Responding with Oxytocin. Although hypnosis has been studied for over a 100 years, little is understood about the neuroscience of hypnosis. This project represents the first investigation of the neural mechanisms underpinning hypnosis. At an applied level, this project has the potential to markedly increase the capacity for Australians to benefit from medical and psychological hypnosis. Hypnosis has been shown to assist in many medical and psychological conditions, and by d ....Enhancing Hypnotic Responding with Oxytocin. Although hypnosis has been studied for over a 100 years, little is understood about the neuroscience of hypnosis. This project represents the first investigation of the neural mechanisms underpinning hypnosis. At an applied level, this project has the potential to markedly increase the capacity for Australians to benefit from medical and psychological hypnosis. Hypnosis has been shown to assist in many medical and psychological conditions, and by developing the means to increase hypnotic responding, this project can directly enhance the physical and psychological health of Australians.Read moreRead less
Neurobiological bases for depression and anxiety: Towards an integrative model of emotion disorders. This study has five areas of national benefit. National research priority: This study will provide a basis for better understanding the underlying neural processes which distinguish these disorders and for developing more targeted treatments. Advancing the field: It will have significant implications for current theoretical models of emotion by integrating existing models and extending them. Inte ....Neurobiological bases for depression and anxiety: Towards an integrative model of emotion disorders. This study has five areas of national benefit. National research priority: This study will provide a basis for better understanding the underlying neural processes which distinguish these disorders and for developing more targeted treatments. Advancing the field: It will have significant implications for current theoretical models of emotion by integrating existing models and extending them. Intellectual leadership: It will promote Australian research in international affective neuroscience. Collaboration: It will draw upon a multidisciplinary approach consistent with the National Research priorities to foster collaborations. Training: It will provide students the opportunity to learn both specific knowledge and important generic skills.Read moreRead less
Cerebral plasticity or early vulnerability? Identifying critical periods for childhood development and recovery. The primary aim of the study is to identify critical time periods during brain development when an insult will have more deleterious consequences for recovery and outcome. The study will also examine the impact of other potential influences to recovery following early brain disease, and determine whether their impact varies across development. Finally, the study will investigate wh ....Cerebral plasticity or early vulnerability? Identifying critical periods for childhood development and recovery. The primary aim of the study is to identify critical time periods during brain development when an insult will have more deleterious consequences for recovery and outcome. The study will also examine the impact of other potential influences to recovery following early brain disease, and determine whether their impact varies across development. Finally, the study will investigate whether specific cognitive and behavioural domains are differentially effected, depending on their maturity at the time of brain insult. Findings from this study will inform the development of conceptual models of early brain insult and recovery of function, and contribute to clinical practice.Read moreRead less
Biased information processing in anxiety: Low anxiety scores, but still at risk. Information processing in anxious persons is biased if confronted with threatening stimulus materials such as words or pictures. This finding has considerable implications for our understanding of fear acquisition and maintenance and for the design of therapeutic interventions. More recent research has shown, however, that low anxious persons who employ repressive coping styles show similar biases. The present proj ....Biased information processing in anxiety: Low anxiety scores, but still at risk. Information processing in anxious persons is biased if confronted with threatening stimulus materials such as words or pictures. This finding has considerable implications for our understanding of fear acquisition and maintenance and for the design of therapeutic interventions. More recent research has shown, however, that low anxious persons who employ repressive coping styles show similar biases. The present project will follow up on these findings by combining the expertises of the two CIs in contemporary cognitive and psychophysiological research. It will not only provide new insights, but also offer research opportunities for postgraduate students, and prospects for future collaborative funding.Read moreRead less
Human learning of likes and dislikes: A test of the dual process account and an investigation of its neural substrates. Dual process accounts of human affective learning hold that affective learning, the learning of likes and dislikes, and relational learning, the learning of predictive relationships, reflect separate learning mechanisms. Affective learning, for instance, is said not to extinguish, a claim that has far reaching consequences for the design of behaviourally based treatments of a ....Human learning of likes and dislikes: A test of the dual process account and an investigation of its neural substrates. Dual process accounts of human affective learning hold that affective learning, the learning of likes and dislikes, and relational learning, the learning of predictive relationships, reflect separate learning mechanisms. Affective learning, for instance, is said not to extinguish, a claim that has far reaching consequences for the design of behaviourally based treatments of anxiety. The project will test this and other predictions of dual process accounts. Moreover, it will extent the experimental analysis of affective learning to the acquisition of likes and identify the cortical bases for aversive, appetitive, and relational learning using event related functional magnetic resonance imaging.Read moreRead less
Assessment of circadian and light interactions in adolescent sleepiness. This project aims to examine the relative contributions of multiple biological clock and sleep factors that may be linked to cognitive function and sleepiness in adolescents. Over 70 per cent of adolescents in Australia experience insufficient sleep. Cross-sectional studies have shown that insufficient sleep and mistimed sleep lead to reduced cognitive function. The project intends to identify specific sleep and circadian m ....Assessment of circadian and light interactions in adolescent sleepiness. This project aims to examine the relative contributions of multiple biological clock and sleep factors that may be linked to cognitive function and sleepiness in adolescents. Over 70 per cent of adolescents in Australia experience insufficient sleep. Cross-sectional studies have shown that insufficient sleep and mistimed sleep lead to reduced cognitive function. The project intends to identify specific sleep and circadian markers that are linked to academic performance, and generate innovative algorithms that predict these associations. The project will provide new knowledge to drive prevention and early intervention programs that use sleep-wake and light exposure information to improve sleep quality.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882219
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
Infrastructure for an integrated cognitive neurophysiological research facility: Mapping the neurobiology of memory and language. The Integrated Cognitive Neurophysiological Research Facility will enhance Australia's national research capacity in cognitive neuroscience by enabling large numbers of researchers and graduate students to investigate the neuroscience of memory and language in a collaborative, multi-disciplinary research environment. The facility will deliver national benefits by unco ....Infrastructure for an integrated cognitive neurophysiological research facility: Mapping the neurobiology of memory and language. The Integrated Cognitive Neurophysiological Research Facility will enhance Australia's national research capacity in cognitive neuroscience by enabling large numbers of researchers and graduate students to investigate the neuroscience of memory and language in a collaborative, multi-disciplinary research environment. The facility will deliver national benefits by uncovering the ways in which areas of the brain are used to remember events and process language. This information can then be used to understand how damage to the brain (such as in stroke or disease) can disrupt memory and language and subsequently lead to more effective neurorehabilitation techniques.Read moreRead less
Assessment of Executive Function in Children and Adults. This project aims to develop tests for executive function that are better grounded in the theory of cognitive processes, have sound measurement properties, and are more efficient, than existing measures. Executive functions entail planning, self-evaluation and adaptation to novel situations. Executive function deficits are found in children and adults who have suffered injury to the frontal regions of the brain, in some ageing adults, and ....Assessment of Executive Function in Children and Adults. This project aims to develop tests for executive function that are better grounded in the theory of cognitive processes, have sound measurement properties, and are more efficient, than existing measures. Executive functions entail planning, self-evaluation and adaptation to novel situations. Executive function deficits are found in children and adults who have suffered injury to the frontal regions of the brain, in some ageing adults, and in certain clinical groups such as autistics. Ability to cope with complexity is a factor in executive functioning, and this will be assessed utilising a new approach to analysis of cognitive complexity.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100177
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
A flexible high throughput analytical system for psychopharmacology and drug discovery. A sensitive new liquid chromatography mass spectrometer will enable a team of leading researchers to detect drugs of abuse and therapeutic drugs in the brain and body as well as levels of hormones, peptides and neurotransmitters. This will enhance a large number of projects examining new treatments for addictive disorders and mental illness.