Action-related learning and plasticity in the cortico-striatal network. This project focuses on the neural bases of adaptive behaviour, specifically on the neural processes through which new actions are acquired. This project aims to establish the neural networks involved as well as the locus of the critical cellular plasticity mediating this learning process in the brain.
Discovery Early Career Researcher Award - Grant ID: DE130101393
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Neurobiological mechanisms of decision under uncertainty. The purpose of this project is to understand the behavioural and brain mechanisms underlying decision under uncertainty. This research will uncover the effect that normal variation in brain networks has on choice and contribute to a better understanding of disorders linked to intolerance of uncertainty.
Discovery Early Career Researcher Award - Grant ID: DE180100344
Funder
Australian Research Council
Funding Amount
$383,551.00
Summary
Neural integration of feedforward and feedback circuits for decision-making. The aim of this project is to discover how cells in the brain combine different types of information to allow decisions to be made. This project will focus on the part of the brain that integrates multiple sources of information to guide choices to accomplish behavioural goals. Using novel electrophysiological and engineering techniques, this project intends to measure the influence of sensory and cognitive information ....Neural integration of feedforward and feedback circuits for decision-making. The aim of this project is to discover how cells in the brain combine different types of information to allow decisions to be made. This project will focus on the part of the brain that integrates multiple sources of information to guide choices to accomplish behavioural goals. Using novel electrophysiological and engineering techniques, this project intends to measure the influence of sensory and cognitive information relayed by other brain areas, and to determine how this correlates with behaviour. The intended outcome of this project is a new understanding of how information is processed in brain cells. This should benefit the development of neural engineering devices.Read moreRead less
The Neural Bases of Decision-Making. The smooth integration of cognitive and emotional processes is necessary for everyday decisions. Dysfunction in this integrative capacity accompanies dementia, neurodegenerative conditions and major psychiatric disorders. This project seeks to understand the neural bases of this integration in normal decision-making using cutting edge behavioural, cellular, molecular and genetic tools to map the neural system, circuit and cellular processes controlling the se ....The Neural Bases of Decision-Making. The smooth integration of cognitive and emotional processes is necessary for everyday decisions. Dysfunction in this integrative capacity accompanies dementia, neurodegenerative conditions and major psychiatric disorders. This project seeks to understand the neural bases of this integration in normal decision-making using cutting edge behavioural, cellular, molecular and genetic tools to map the neural system, circuit and cellular processes controlling the selection, evaluation and choice of goal-directed actions. Such actions can, with continued practice, transition into relatively inflexible habits. Thus, this project aims to investigate the neural processes that mediate this transition and how actions and habits interact in normal decision-making.Read moreRead less
The neural bases of decision-making. The aim of this project is to understand the brain circuits controlling voluntary or goal-directed actions and particularly the memory processes that contribute to such actions. Goal-directed action is a fundamental capacity necessary for normal decision-making that is significantly attenuated by normal aging. This project aims to establish the neural circuits engaged in encoding new goal-directed actions, how this encoding is accomplished without interfering ....The neural bases of decision-making. The aim of this project is to understand the brain circuits controlling voluntary or goal-directed actions and particularly the memory processes that contribute to such actions. Goal-directed action is a fundamental capacity necessary for normal decision-making that is significantly attenuated by normal aging. This project aims to establish the neural circuits engaged in encoding new goal-directed actions, how this encoding is accomplished without interfering with pre-existing memories and how these memories are later retrieved to guide planning and performance. Understanding the determinants of such actions will enable the development of novel ways to treat ageing-related deficits in decision-making with significant economic benefits. Read moreRead less
ARC Centre of Excellence for Integrative Brain Function. The Centre of Excellence for Integrative Brain Function will address one of the greatest scientific challenges of the 21st century to understand how the brain works. We will investigate complex functions such as attention, prediction and decision-making, which require the coordination of information processing by many areas of the brain. This will require a highly collaborative approach involving neurobiologists, cognitive scientists, eng ....ARC Centre of Excellence for Integrative Brain Function. The Centre of Excellence for Integrative Brain Function will address one of the greatest scientific challenges of the 21st century to understand how the brain works. We will investigate complex functions such as attention, prediction and decision-making, which require the coordination of information processing by many areas of the brain. This will require a highly collaborative approach involving neurobiologists, cognitive scientists, engineers and physicists, allowing us to translate our discoveries into novel technologies for the social and economic benefit of all Australians. We will also train a new generation of multidisciplinary researchers, and contribute our expertise to a range of public education and awareness programs.Read moreRead less