How Does Glucose Protect The Retina And Optic Nerve Against Ischaemia?
Funder
National Health and Medical Research Council
Funding Amount
$418,171.00
Summary
Raised blood sugar levels are generally considered to be bad for nerve cells, especially those in the eye. But we have made a groundbreaking discovery finding that in the short-term, sugar can rescue nerve cells in the eye from death caused by lack of blood flow. In this project we will investigate how this remarkable effect is achieved.
Glaucoma Causes Secondary Neurodegeneration In The Brain
Funder
National Health and Medical Research Council
Funding Amount
$380,891.00
Summary
Glaucoma is one of the commonest causes of irreversible blindness worldwide. The optic nerve have been considered as the primary site of glaucomatous damage. However, recent evidence suggests that glaucoma may not merely be an eye disease, because secondary changes have also been observed in the higher visual centres in glaucoma patients. In this proposed study, topographically related degeneration along the visual pathway will be monitored using advanced MRI technology.