Axon Degeneration And Axon Protection In CNS Disease And Injury
Funder
National Health and Medical Research Council
Funding Amount
$389,120.00
Summary
One of the major reasons for the clinical symptoms of neurological diseases such as Alzheimer’s disease and Motor Neuron Disease is the loss of connections between the nerve cells. Nerve cells are connected by specialized processes called axons. In disease these processes can breakdown. This project specifically looks at how axons break down in disease and tests therapeutic strategies to protect them.
The Role Of Excitotoxicity In Mediating Distal Axonal Degneration In ALS
Funder
National Health and Medical Research Council
Funding Amount
$392,952.00
Summary
Amyotrophic lateral sclerosis (ALS), the major cause of motor neuron disease, is a devastating diseasse for which there is no cure. There have been significant advances in understanding the pathology of ALS yet we still don’t know what causes the dying back of spinal motor neurons. We have new evidence that suggests that ALS may, in part, be caused by excitotoxcity - or over stimulation - of neurons in the spinal cord. We will follow this lead using a range of cutting edge experimental models.
De-tabooing depression and anxiety: Mental health communication in old age. This project aims to uncover how older Australians talk about and understand depression and anxiety, and it seeks to raise awareness of these debilitating conditions via new media. There has been much medical research in this area, and while language has been identified as highly relevant for recovery, little is known of how people express their experiences around mental well-being. The research gap is even wider for the ....De-tabooing depression and anxiety: Mental health communication in old age. This project aims to uncover how older Australians talk about and understand depression and anxiety, and it seeks to raise awareness of these debilitating conditions via new media. There has been much medical research in this area, and while language has been identified as highly relevant for recovery, little is known of how people express their experiences around mental well-being. The research gap is even wider for the worst affected in the population — older adults. These illnesses are shrouded in taboo, and symptoms often go undetected. The expected outcomes of the project are improved communication about mental well-being and the celebration of the lives and stories of older Australians — an integral but vulnerable segment of society.Read moreRead less
Chinese imprint on Tasmania and consequent connnections with China. The project identifies and analyses Chinese cultural heritage in Tasmania and consequent connections with China. It will establish the veracity of life and work of Chinese settlers in Tasmania and of their descendants in China as a result. It will analyse Chinese traditional cultural values that underlined migrant motivation and behaviour patterns. Finally it will analyse how their connections with Tasmania influenced life of th ....Chinese imprint on Tasmania and consequent connnections with China. The project identifies and analyses Chinese cultural heritage in Tasmania and consequent connections with China. It will establish the veracity of life and work of Chinese settlers in Tasmania and of their descendants in China as a result. It will analyse Chinese traditional cultural values that underlined migrant motivation and behaviour patterns. Finally it will analyse how their connections with Tasmania influenced life of their descendants. The project will provide intellectual content for local community to establish Chinese aspect of cultural heritage and find a niche tourist market for affluent Chinese from where their ancestors came to Tasmania.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140101412
Funder
Australian Research Council
Funding Amount
$383,532.00
Summary
The New Politics of Food and the Australian Media. The provenance of food and the ethics of food production and consumption are increasingly a focus of mainstream media, including television cooking shows, cookbooks, advertising, news and online media. This is the result of alliances between the media and the food industries, alliances that are reinvesting food and food politics with new meaning and significance. This project investigates the complex dynamics of interaction between these two imp ....The New Politics of Food and the Australian Media. The provenance of food and the ethics of food production and consumption are increasingly a focus of mainstream media, including television cooking shows, cookbooks, advertising, news and online media. This is the result of alliances between the media and the food industries, alliances that are reinvesting food and food politics with new meaning and significance. This project investigates the complex dynamics of interaction between these two important Australian industries by examining their texts, economies and practices. It will reveal their significant effects on corporate decision-making, consumer behaviours, public debate and national policy.Read moreRead less
The Lively Regional City: Mapping City Centre ‘Assemblages’ that Work. This project analyses city centre revitalisation processes and policies in the context of regional Australia. Working with Wollongong City Council, the project aims to provide an evidence-based analysis of how the Wollongong city centre is perceived, regarded and used by its residents and visitors, paying particular attention to those aspects considered either 'lively' or 'dead'; its goal is to interrogate revitalisation poli ....The Lively Regional City: Mapping City Centre ‘Assemblages’ that Work. This project analyses city centre revitalisation processes and policies in the context of regional Australia. Working with Wollongong City Council, the project aims to provide an evidence-based analysis of how the Wollongong city centre is perceived, regarded and used by its residents and visitors, paying particular attention to those aspects considered either 'lively' or 'dead'; its goal is to interrogate revitalisation policy frameworks and create decision-making tools to inform planning processes for long-term city centre revitalisation and sustainable economic growth; and identify opportunities for innovative city centre planning in Wollongong to contribute to the regions sustainable transformation, long-term growth, employment and community development.Read moreRead less
Reconfiguring intimate life: Gender and sexuality as sites of national redefinition in Australia since 1996. This project opens up current thinking about the nature of change in twenty-first century life in Australia by focusing on issues of gender and sexuality. It draws critical attention to a field of contest and re-negotiation of national identity and belonging, thus far not identified, that has far-reaching effects for the national fabric. It provides opportunities for thinking about sexual ....Reconfiguring intimate life: Gender and sexuality as sites of national redefinition in Australia since 1996. This project opens up current thinking about the nature of change in twenty-first century life in Australia by focusing on issues of gender and sexuality. It draws critical attention to a field of contest and re-negotiation of national identity and belonging, thus far not identified, that has far-reaching effects for the national fabric. It provides opportunities for thinking about sexual and reproductive relationships in ways that can be open to voices, stories and forms of belonging that signal a more generous, sustainable and healthy non-violent future.
The impact of the project will be on professional and scholarly training, teaching and research across a variety of disciplinary areas, as well as public debate. Read moreRead less
A project to examine and strengthen health care incident disclosure communication. Incidents occur frequently in health care, killing or maiming around 18,000 people per year. This study will map the experiences of patients and clinicians of conducting clinical incident discussions to enhance understanding of post-incident communication dynamics and develop models that facilitate incident communication.
Transnational Environmental Campaigns in the Australia-Asian Region. Conflict over environments, resources and landscapes has become a feature of contemporary political life. Increasingly, these conflicts are articulated, negotiated and potentially resolved across national boundaries and complex networks of media and communications. In the context of intensifying pressure for resource access, market opportunities and changing media practices in Australia and the Asian region, it is critical to e ....Transnational Environmental Campaigns in the Australia-Asian Region. Conflict over environments, resources and landscapes has become a feature of contemporary political life. Increasingly, these conflicts are articulated, negotiated and potentially resolved across national boundaries and complex networks of media and communications. In the context of intensifying pressure for resource access, market opportunities and changing media practices in Australia and the Asian region, it is critical to examine how competing environmental claims are mediated, and how this mediation influences public debate, policy and market viability. Providing evidence-based analysis of transnational conflicts as they emerge and travel, this project is expected to inform debate on Australia's environmental and economic sustainability.Read moreRead less
The role of turgor in hyphal extension of the Ascomycete Neurospora crassa. Cellular expansion is an absolute necessity during the growth and development of plants and fungi. This process relies heavily upon the accumulation of inorganic ions. Osmotically driven water influx then creates the hydrostatic pressure that underlies the increase in cell volume. Cellular expansion is normally asymmetric and localised in one small region, such as hyphal tip. How does the cell maintain the turgor that dr ....The role of turgor in hyphal extension of the Ascomycete Neurospora crassa. Cellular expansion is an absolute necessity during the growth and development of plants and fungi. This process relies heavily upon the accumulation of inorganic ions. Osmotically driven water influx then creates the hydrostatic pressure that underlies the increase in cell volume. Cellular expansion is normally asymmetric and localised in one small region, such as hyphal tip. How does the cell maintain the turgor that drives expansion? How is expansion controlled spatially? These questions will be addressed in this project by comprehensive study of ion transport processes in a model organism, Neurospora crassa, using osmotic sensitive and transport mutants.Read moreRead less