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Discovery Early Career Researcher Award - Grant ID: DE120102961
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
The role of the unfolded protein response in tau neurobiology and pathology. The main role of the protein tau is the stabilisation of the scaffolding of cells. In a group of dementias, tau forms abnormal clumps within the cells of the brain causing them to die. This project will investigate the cellular processes involved in normally preventing tau proteins from clumping and their role in the development of the abnormal tau clumps.