Complexity-manageable methodologies and efficient computational tools for analysis and design of large-scale systems. The tools to be developed in this project have impact on a broad range of disciplines, including system analysis, feedback control technology, signal processing, communication network, and information theory. Practically, the success of this project will create cutting edge technologies applicable to design and management of important infrastructures of the modern society such as ....Complexity-manageable methodologies and efficient computational tools for analysis and design of large-scale systems. The tools to be developed in this project have impact on a broad range of disciplines, including system analysis, feedback control technology, signal processing, communication network, and information theory. Practically, the success of this project will create cutting edge technologies applicable to design and management of important infrastructures of the modern society such as communication networks, transportation systems, electrical power grids, and collaborative intelligent machines, and water distribution networks. Success of this project will bring novel methodologies and computational tools which help engineers to systematically design and validate the performance of their engineering systems.Read moreRead less
Robustness Analysis and Control Design of Distributed and Networked Systems. The theory and computational tools to be developed in this project have impact on a broad range of areas, including various engineering disciplines, biology, and medical and environmental sciences. In terms of practical interests, this project will create cutting edge technologies which are applicable to important infrastructures of the modern society such as communication networks, transportation systems, electrical po ....Robustness Analysis and Control Design of Distributed and Networked Systems. The theory and computational tools to be developed in this project have impact on a broad range of areas, including various engineering disciplines, biology, and medical and environmental sciences. In terms of practical interests, this project will create cutting edge technologies which are applicable to important infrastructures of the modern society such as communication networks, transportation systems, electrical power grids, collaborative intelligent machines, and water distribution networks. Read moreRead less
Development of Control Methodologies for Drug Dosing in Biomedical Engineering. This research proposal is very relevant to the National Research Priorities in the areas of Frontier Technologies and Breakthrough science. At a broader level, we aim to assist in the development of a national competence in what has been an emerging and promising discipline. The research will develop fundamental and enabling laws and techniques for drug administration to regulate physiological variables such as blood ....Development of Control Methodologies for Drug Dosing in Biomedical Engineering. This research proposal is very relevant to the National Research Priorities in the areas of Frontier Technologies and Breakthrough science. At a broader level, we aim to assist in the development of a national competence in what has been an emerging and promising discipline. The research will develop fundamental and enabling laws and techniques for drug administration to regulate physiological variables such as blood pressure and degree of consciousness in critical care patients.Read moreRead less
Modelling and estimation methods for discrete multi-dimensional systems. Multi-dimensional signal processing plays a role in a variety of application areas, ranging from remote sensing for environmental monitoring and geological mapping, to medical imaging and the automatic control of industrial processes. The success of the project will provide mathematical tools for the advancement of the state-of-the-art in these broad areas.
Modelling, Analysis and Synthesis Tools for Multi-Dimensional Signal Processing Systems. Multi-dimensional signal processing plays a role in a variety of application areas, ranging from remote sensing for environmental monitoring and geological mapping, to medical imaging and the automatic control of industrial processes. The success of this project will provide mathematical tools for the advancement of the state-of-the-art in these broad areas.
Derivative free algorithms for large scale nonsmooth and global optimization and their applications. The outcomes expected from this research fall broadly into two categories: 1) the development of a new class of effective readily implementable derivative free techniques for large scale non-smooth and global optimisation and 2) the development of new algorithms based on derivative free optimization techniques for solving data mining, resource allocation problems and some problems in bioinformati ....Derivative free algorithms for large scale nonsmooth and global optimization and their applications. The outcomes expected from this research fall broadly into two categories: 1) the development of a new class of effective readily implementable derivative free techniques for large scale non-smooth and global optimisation and 2) the development of new algorithms based on derivative free optimization techniques for solving data mining, resource allocation problems and some problems in bioinformatics. In particular, the application of these techniques to molecular biology and cluster analysis will be very important for the development of competitive technologies for Australia.
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Patient-specific Computational Tools for Diagnosing and Treating Gait Disorders in Children with Cerebral Palsy. This proposal addresses one of the most fundamental and difficult questions related to the treatment of children with cerebral palsy: Why do these children walk in a crouched position, with excessively bent hips and knees? High-fidelity, patient-specific computer simulations of walking can help to answer this question and, in so doing, can improve the outcomes of orthopaedic surgeries ....Patient-specific Computational Tools for Diagnosing and Treating Gait Disorders in Children with Cerebral Palsy. This proposal addresses one of the most fundamental and difficult questions related to the treatment of children with cerebral palsy: Why do these children walk in a crouched position, with excessively bent hips and knees? High-fidelity, patient-specific computer simulations of walking can help to answer this question and, in so doing, can improve the outcomes of orthopaedic surgeries designed to correct movement abnormalities in these patients. Realistic computer simulations of human movement can play a pivotal role in healthcare through patient rehabilitation; in sports, through the development of personalized training programs for elite athletes; and in entertainment, through the creation of video games and animated films.Read moreRead less
Approximate bundle methods in nonsmooth optimisation and their applications in some complex systems. Non-smooth and non-convex optimisation has many applications in industry and science. One of the powerful methods in non-smooth optimisation is a bundle method. This project will develop new versions of the bundle method by using continuous approximations to the sub-differential and extend this method for solving non-convex (smooth and non-smooth) optimisation problems by using max-min of linear ....Approximate bundle methods in nonsmooth optimisation and their applications in some complex systems. Non-smooth and non-convex optimisation has many applications in industry and science. One of the powerful methods in non-smooth optimisation is a bundle method. This project will develop new versions of the bundle method by using continuous approximations to the sub-differential and extend this method for solving non-convex (smooth and non-smooth) optimisation problems by using max-min of linear functions for the approximation of the functions involved. The outcome will be a new class of effective readily implementable algorithms for the minimization of non-smooth and non-convex functions, whose usefulness will be demonstrated by applications in cluster analysis, biochemistry and robotics.
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Modelling patient flows through hospitals: optimizing effective use of resources. Hospitals are complex, dynamic systems confronted by increased demand in the face of shrinking real capacity. Managing such systems is currently undertaken with sub-optimal analytical support, particularly when demand and capacity are changing and resources must be manipulated to respond to such changes. In this project, the investigators will apply a mathematical modelling approach to the analysis of hospital pati ....Modelling patient flows through hospitals: optimizing effective use of resources. Hospitals are complex, dynamic systems confronted by increased demand in the face of shrinking real capacity. Managing such systems is currently undertaken with sub-optimal analytical support, particularly when demand and capacity are changing and resources must be manipulated to respond to such changes. In this project, the investigators will apply a mathematical modelling approach to the analysis of hospital patient flows. Furthermore, they will employ statistical process control methodologies to the problem of recognising and responding to changes in the flows, so that performance objectives are met. In doing this, they will give health service managers and clinicians a significant advantage in deciding how best to manage a constrained resource to maximize access, throughput and patient outcomes.Read moreRead less
Non-invasive assessment of hip fracture risk in elderly people. No falls, no fractures - this will be the main benefit of the proposed research. The most significant outcome will be new computational tools to improve current understanding of the biomechanics of falls and bone fragility in elderly people, which, in turn, will help to reduce healthcare costs associated with the treatment and management of hip fractures. Realistic models and computer simulations of human movement can play a pivota ....Non-invasive assessment of hip fracture risk in elderly people. No falls, no fractures - this will be the main benefit of the proposed research. The most significant outcome will be new computational tools to improve current understanding of the biomechanics of falls and bone fragility in elderly people, which, in turn, will help to reduce healthcare costs associated with the treatment and management of hip fractures. Realistic models and computer simulations of human movement can play a pivotal role in three of Australia's largest industries: healthcare, through the diagnosis and treatment of movement disorders; sports, through the development of personalized training programs for elite athletes; and entertainment, through the development of video/digital games and animated films.Read moreRead less