Dysfunction In Anterior Cingulate Brain Networks: Implementations For Psychiatric And Substance Use Disorders
Funder
National Health and Medical Research Council
Funding Amount
$380,558.00
Summary
Psychiatric and substance use disorders are associated with significant morbidity and mortality. Recent evidence points to discrete brain networks as being critically involved in the neurobiology of these disorders. Using novel brain imaging techniques, this research will increase our knowledge of how these brain networks are involved in these disorders. This will represent an important step towards elucidating their biological underpinnings and improving outcomes for affected patients.
The Role Of The Zinc Finger Transcriptional Repressor Znf238 During Nerve Cell Maturation
Funder
National Health and Medical Research Council
Funding Amount
$394,264.00
Summary
Proper foetal brain assembly is critical for brain function, but the underlying genetic mechanisms remain poorly defined. In this study, I will investigate a family of proteins that “turn on” neural gene expression in combination with another protein that “turns off” their expression during nerve cell development. Understanding this novel on/off mechanism for controlling gene expression in newborn nerve cells will further our understanding of how the brain is assembled.