Next Generation Cybernetics: Long Term Carbon Fibre Dual Stimulation / Recording Electrode Arrays For Closed Loop Neural Implants
Funder
National Health and Medical Research Council
Funding Amount
$679,670.00
Summary
Electrodes implanted in the brain have enormous potential for treating a range of conditions from epilepsy to control of prosthetics for patients with limb loss. Currently, the electrodes used in such system fail rapidly because they are rejected by the body. We aim to use diamond with ultra-fine carbon fibre electrodes to make arrays that are invisible to the human immune system. Such arrays will function for the lifetime of the patient without needing replacement.
Footprints in instance space: visualising the suitability of optimisation algorithms. Optimisation problems underpin the efficiency and effectiveness of many critical sectors (e.g., healthcare, manufacturing, and defence). The project will provide both practitioners and researchers with powerful new tools to develop a much more robust understanding of the strengths and weaknesses of a variety of optimisation algorithms.
Improving Productivity and Efficiency of Australian Airports – A Real Time Analytics and Statistical Approach. Aviation is a major economic driver both within Australia and overseas, but the aviation industry faces growing challenges from the increase in passengers and changing regulations. To meet these challenges, airports, airlines, government agencies and others need to maximise their efficiency and productivity; however, complex dependencies and differing operational objectives complicate t ....Improving Productivity and Efficiency of Australian Airports – A Real Time Analytics and Statistical Approach. Aviation is a major economic driver both within Australia and overseas, but the aviation industry faces growing challenges from the increase in passengers and changing regulations. To meet these challenges, airports, airlines, government agencies and others need to maximise their efficiency and productivity; however, complex dependencies and differing operational objectives complicate this task. This project aims to develop a real-time, whole-of-system operational performance framework that can help operators in finding and evaluating solutions to maximise throughput, reduce wait times and mitigate flow-on effects. Innovative new video analytic and Bayesian Network based tools are integrated to address the challenges of adaptability and uncertainty.Read moreRead less
Structural Studies On Cell Signalling Via The LIF Receptor And Gp130
Funder
National Health and Medical Research Council
Funding Amount
$453,943.00
Summary
The cytokines play important roles in the immune system during blood cell development and inflammation, and in nerve growth, bone remodeling, reproduction and heart development. Cell responses are initiated by a cytokine bringing together on the cell surface a receptor complex made up of multiple molecules. This project will investigate the atomic structure of the cell surface macromolecular complex, and hence the underlying mechanism by which cytokine signals are initiated.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100023
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
Integrated command and control facility for large-scale critical infrastructure management. This is a test bed facility for achieving sustainable operation of Australia's critical infrastructure, particularly at airports. The facility will enable an integrated and coordinated strategy to increase operational resilience while not losing sight of the complex nature and dynamic requirements of critical infrastructure management.
Mechanisms Underlying Generation Of Febrile Seizures In Mouse Models Of Human Familial Epilepsy
Funder
National Health and Medical Research Council
Funding Amount
$304,559.00
Summary
Febrile Seizures (FS) affect 3% of children aged 0.5 - 6 yrs and have been proposed as an indicator of severe forms of adult generalized epilepsy. Mechanisms underlying FS generation are unknown although studies of Australian families suffering from epilepsy have linked 2 genes to FS. We have generated mice expressing these 2 genes. Aims and Outcomes: to investigate events triggering FS which will provide important insights into why FS occurs in children. (NB: CIA 2 yr career interruption)