"I think; therefore I am": Loneliness and neurodevelopmental disorders. This project aims to develop a 3-D animated program for adolescents with neurodevelopmental disorders (NDDs) that alters the automatic biases arising from their everyday social communication difficulties (including via social media), which result in negative thought patterns and loneliness. Negative thought patterns, which are arguably the hallmarks of, and causal in, the development of emotional dysfunction are amplified by ...."I think; therefore I am": Loneliness and neurodevelopmental disorders. This project aims to develop a 3-D animated program for adolescents with neurodevelopmental disorders (NDDs) that alters the automatic biases arising from their everyday social communication difficulties (including via social media), which result in negative thought patterns and loneliness. Negative thought patterns, which are arguably the hallmarks of, and causal in, the development of emotional dysfunction are amplified by loneliness, and adolescents with NDDs experience significantly greater levels of loneliness. Altering these negative thought patterns via an engaging 3-D animated program offers great potential to improve educational and social-emotional outcomes along with generating economic benefits nationally and internationally.Read moreRead less
Neurodevelopmental disorders and loneliness: School predictors & outcomes. This project aims to establish trajectories of loneliness across the 10-18 year developmental period in adolescents with neuro-developmental disorders (NDDs). This is significant because adolescence is the peak period for loneliness and the social communication difficulties experienced by adolescents with NDDs place them at greater risk of loneliness. Lower levels of school attendance, connectedness and mental well-being, ....Neurodevelopmental disorders and loneliness: School predictors & outcomes. This project aims to establish trajectories of loneliness across the 10-18 year developmental period in adolescents with neuro-developmental disorders (NDDs). This is significant because adolescence is the peak period for loneliness and the social communication difficulties experienced by adolescents with NDDs place them at greater risk of loneliness. Lower levels of school attendance, connectedness and mental well-being, and higher rates of disruptive behaviour, expulsion, drop-out, depression, social withdrawal, and suicide ideation are strongly linked to loneliness. Therefore predicting critical times in trajectories will enhance emotional, behavioural and school related outcomes and optimise economic, societal and quality of life benefits.Read moreRead less
Structural relations of loners' loneliness and antisocial behaviour in children and adolescents: building a conceptual model for effective intervention. This is the first research project to develop a conceptual model of loneliness and detached a-loneness to explain the contribution of loneliness to childhood and adolescent antisocial behaviour. The outcome will be a school-based web delivered program which will have a major impact on promoting the healthy development of young Australians.
Nonlinear spatial and spatiotemporal econometrics: theory with applications. Modern societies like Australia have major challenges in the forecasting, measuring and managing of risks associated with global economic and environmental/climate changes. These tasks require advanced econometric techniques in modelling and forecasting of complex nonlinear spatiotemporal variability in economic and social systems. This project will develop frontier econometric technologies that enable more accurate eco ....Nonlinear spatial and spatiotemporal econometrics: theory with applications. Modern societies like Australia have major challenges in the forecasting, measuring and managing of risks associated with global economic and environmental/climate changes. These tasks require advanced econometric techniques in modelling and forecasting of complex nonlinear spatiotemporal variability in economic and social systems. This project will develop frontier econometric technologies that enable more accurate economic and climate forecasts. The tools produced will provide Australia's scientists and policy-makers with a greater capacity to manage the risks associated with these challenges. A side-benefit of the research will be high-quality publications that enhance the nation's reputation in this cutting edge research.Read moreRead less
Nonlinear Panel Data Econometrics: Theory and Practice. This research addresses the ARC National Research Priorities Goal of 'An Environmentally Sustainable Australia', specifically 'Reducing and capturing emissions in transport and energy generation'. Avoiding, managing, and/or adapting to the climate change impacts is now the most pressing global environmental problem. This project will produce tangible and original insights into policy options for institutional adjustment to future climate ....Nonlinear Panel Data Econometrics: Theory and Practice. This research addresses the ARC National Research Priorities Goal of 'An Environmentally Sustainable Australia', specifically 'Reducing and capturing emissions in transport and energy generation'. Avoiding, managing, and/or adapting to the climate change impacts is now the most pressing global environmental problem. This project will produce tangible and original insights into policy options for institutional adjustment to future climate change in Australia; will provide insight into the scope for positive community behavioural change; and possible transformations in Australian social debate to maximise adaptive capacity. It will also strengthen and produce original conceptual approaches and research methods.Read moreRead less
Speech production in language-impaired speakers: Informing theoretical models and clinical practice regarding grammatical processing. This research examines how language is stored and processed in our minds and the ways this can go wrong. By improving our theory of language processing, the research will result in improved diagnosis and treatment for the ten per cent of Australians who suffer from communication impairment.
ARC Financial Integrity Research Network. The integrity of the financial system is constantly under stress because of the development of ever more complex financial instruments, structures and strategies, and the associated research technologies that continues to accelerate worldwide. FIRN's vision is to harness the considerable strengths of Australia's internationally renowned finance, accounting and economics researchers into a research agenda to address issues concerning the integrity of the ....ARC Financial Integrity Research Network. The integrity of the financial system is constantly under stress because of the development of ever more complex financial instruments, structures and strategies, and the associated research technologies that continues to accelerate worldwide. FIRN's vision is to harness the considerable strengths of Australia's internationally renowned finance, accounting and economics researchers into a research agenda to address issues concerning the integrity of the financial system. It will enable Australian research in this area to match the scale and impact of similar research in other major international financial centres, and play an essential role in placing Australia among the world's leaders in financial markets related research.Read moreRead less
Melanoma Mutation Profiling For Personalised Treatment
Funder
National Health and Medical Research Council
Funding Amount
$571,191.00
Summary
Melanoma is an aggressive skin cancer, and the leading cause of skin cancer related deaths. Disease spread is difficult to detect and extremely difficult to cure. This bleak clinical outcome is changing with the development of personalised therapies which include small molecule inhibitors to treat metastatic melanoma. Here we seek to identify the spectrum of mutations in patient tumours and circulating tumour cells for advanced personalised treatment.
Identifying Glaucoma Risk Variants In The Norfolk Island Genetic Isolate
Funder
National Health and Medical Research Council
Funding Amount
$658,447.00
Summary
Primary open angle glaucoma is the most common form of glaucoma. In this project we will focus on the identification of functional genetic variants influencing development of this disorder, using a powerful whole exome sequencing approach in a large multigenerational pedigree from the Norfolk Island population isolate. The identification of genes influencing glaucoma development would provide invaluable clues to aid in defining the pathophysiology of this common disease.
Bifurcation analysis with applications to design of power electronics systems. This project represents a fundamental study of nonlinear dynamics in power electronics systems. We expect that this project will result in knowledge advancement and technological innovations. In particular, rigorous algorithms will be resulted for the identification and analysis of nonlinear phenomena in power electronics systems. Special attention will be paid to design applications of power electronics systems. The ....Bifurcation analysis with applications to design of power electronics systems. This project represents a fundamental study of nonlinear dynamics in power electronics systems. We expect that this project will result in knowledge advancement and technological innovations. In particular, rigorous algorithms will be resulted for the identification and analysis of nonlinear phenomena in power electronics systems. Special attention will be paid to design applications of power electronics systems. The successful implementation of these methods and algorithms will definitely lead to development of frontier technology in engineering science, which is a National Priority Goal. Read moreRead less