Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for l ....Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for liposomes. This provides a significant PhD training opportunity and brings an international focus to the development of planar patch-clamp electrophysiology in Australia. The project has significant commercial potential by developing both the planar patch-clamp electrophysiology techniques for liposomes and producing a novel biomimetic mechanosensitive biosensor.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668446
Funder
Australian Research Council
Funding Amount
$530,000.00
Summary
Nano-positioning facility for nano-scale measurement and manipulation. Nanotechnology is the science of understanding and control of matter at dimensions of 100 nanometers or less. Encompassing nanoscale science, engineering, and technology, nanotechnology involves imaging, measuring, modeling, and manipulation of matter at this level of precision. An important aspect of research in nanotechnology involves precision control and manipulation of devices and materials at a nanoscale, i.e. nanoposi ....Nano-positioning facility for nano-scale measurement and manipulation. Nanotechnology is the science of understanding and control of matter at dimensions of 100 nanometers or less. Encompassing nanoscale science, engineering, and technology, nanotechnology involves imaging, measuring, modeling, and manipulation of matter at this level of precision. An important aspect of research in nanotechnology involves precision control and manipulation of devices and materials at a nanoscale, i.e. nanopositioning. The primary goal of this proposal is the establishment of an experimental nanopositioning research facility to enable the development of a new generation of nanopositioners. Establishment of the facility will give Australia's nanotechnology researchers a unique enabling facility in this high-tech field.Read moreRead less
Advanced model-based control for ultra-fast and ultra-high-precision nanoscale positioning. Australia faces unique challenges due to its small population and distance from international markets. To maintain a high standard of living Australia needs to further develop its high-tech base particularly in emerging fields such as nanotechnology. This research program is aimed at placing Australia at the forefront of international research in nanoscale positioning systems by building a world-class tea ....Advanced model-based control for ultra-fast and ultra-high-precision nanoscale positioning. Australia faces unique challenges due to its small population and distance from international markets. To maintain a high standard of living Australia needs to further develop its high-tech base particularly in emerging fields such as nanotechnology. This research program is aimed at placing Australia at the forefront of international research in nanoscale positioning systems by building a world-class team of talented researchers and equipping them with world-class research infrastructure. The global market for nanotechnology is projected to be in the tens of billions of dollars by 2020. The proposed research will enhance Australia's competitive advantage through high-impact scientific and technological innovations in nanotechnology.Read moreRead less
Optically-driven micromachines and microtools. The use of optical forces to trap and manipulate microscopic particles has developed from a novelty into a widely used versatile research tool - optical tweezers. New advances, such as the application and optical measurement of optical torque, have been brought to the brink of practical application. We will apply these methods to the development and production of micromachines of unprecedently small size, and the development of new medical diagnosti ....Optically-driven micromachines and microtools. The use of optical forces to trap and manipulate microscopic particles has developed from a novelty into a widely used versatile research tool - optical tweezers. New advances, such as the application and optical measurement of optical torque, have been brought to the brink of practical application. We will apply these methods to the development and production of micromachines of unprecedently small size, and the development of new medical diagnostic techniques, and industrial and research tools.Read moreRead less
Exploring the Dynamics of Nanostructure Self-Organisation during Compound Semiconductor Epitaxy. The application of LEEM to GaAs and InAs will be a world first, positioning Australia at the forefront of nanoscale self-organisation, leading to important international recognition and publicity. The spectacular movies obtained will revolutionise our basic understanding of compound semiconductor self-organisation and facilitate an improved control over nanostructure fabrication using MBE. This will ....Exploring the Dynamics of Nanostructure Self-Organisation during Compound Semiconductor Epitaxy. The application of LEEM to GaAs and InAs will be a world first, positioning Australia at the forefront of nanoscale self-organisation, leading to important international recognition and publicity. The spectacular movies obtained will revolutionise our basic understanding of compound semiconductor self-organisation and facilitate an improved control over nanostructure fabrication using MBE. This will generate entirely new device structures relevant to the frontier technologies of photonics and quantum information processing. The project will provide high level training for post-graduate and honours students in nanoscale characterisation and synchrotron science.Read moreRead less
Advanced high resolution atomic force microscopy of biomolecules in physiological environments. The proposed research is intended to explain high resolution bioimaging problems addressed only phenomenologically before. A correct physical model would help the scientific community to optimise imaging of dynamic biological systems, extending our knowledge about the way living organisms function. With dynamic bioimaging, the mechanism of certain diseases such as Alzheimer's - where biomolecule fiber ....Advanced high resolution atomic force microscopy of biomolecules in physiological environments. The proposed research is intended to explain high resolution bioimaging problems addressed only phenomenologically before. A correct physical model would help the scientific community to optimise imaging of dynamic biological systems, extending our knowledge about the way living organisms function. With dynamic bioimaging, the mechanism of certain diseases such as Alzheimer's - where biomolecule fiber formation plays a key role - can also be addressed, thus the project has even therapeutical relevance. Furthermore, adequate description of liquid phase imaging can help engineers in the design of better hardware and software solutions, for the benefit of the bio-nanotechnological industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453320
Funder
Australian Research Council
Funding Amount
$347,886.00
Summary
Advanced Spectroscopy for Nano-characterisation of Materials Chemistry and Properties. This application proposes to establish a cutting-edge spectroscopic facility which includes; electron energy-loss spectroscopy (EELS), energy-dispersive X-ray spectroscopy (EDS), cathodoluminescence (CL), photoluminescence (PL) and micro-Raman spectroscopy. Each of the spectrometers to be installed has significantly higher sensitivity and resolution than any other facility available in Australia and is capable ....Advanced Spectroscopy for Nano-characterisation of Materials Chemistry and Properties. This application proposes to establish a cutting-edge spectroscopic facility which includes; electron energy-loss spectroscopy (EELS), energy-dispersive X-ray spectroscopy (EDS), cathodoluminescence (CL), photoluminescence (PL) and micro-Raman spectroscopy. Each of the spectrometers to be installed has significantly higher sensitivity and resolution than any other facility available in Australia and is capable of full spectrum imaging. This new spectroscopic infrastructure will enable the knowledge-based development of new materials by allowing complete characterisation of structure-composition-property relationships at the nanometre level.Read moreRead less
Separating Subtle Interplay between Competing/Cooperating Superconductivity and Magnetism in YBa2Cu3O7-x with Nanotechnology. Superconducting cables can carry 100 to 200 times more electric current than conventional cables. The innovations in this program could enable the widespread commercialization of more efficient types of power generation, transmission, and electrical equipment and devices, offering tremendous energy savings and emissions reductions. It is estimated that ~A$400 million pe ....Separating Subtle Interplay between Competing/Cooperating Superconductivity and Magnetism in YBa2Cu3O7-x with Nanotechnology. Superconducting cables can carry 100 to 200 times more electric current than conventional cables. The innovations in this program could enable the widespread commercialization of more efficient types of power generation, transmission, and electrical equipment and devices, offering tremendous energy savings and emissions reductions. It is estimated that ~A$400 million per year can be saved if high-Tc superconducting wires and cables were to replace conventional metallic conductors. The success of this program will greatly increase scientific understanding of hig-Tc superconductivity and expand Australia's knowledge in the research on high-Tc superconductors. The training will also provide scientific talents to the country.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453879
Funder
Australian Research Council
Funding Amount
$184,163.00
Summary
Electron beam induced deposition and ablation nanofabrication facility. Electron beam induced deposition and ablation(EBIDA) is rapidly emerging as a new technology capable of fabricating three-dimensional nanostructures on nearly any substrate with very high precision. This proposal aims to establish a nanoscale EBIDA facility by integrating a specialized nanolithography attachment with an existing state-of-the-art 1nm resolution high current variable pressure scanning electron microscope. This ....Electron beam induced deposition and ablation nanofabrication facility. Electron beam induced deposition and ablation(EBIDA) is rapidly emerging as a new technology capable of fabricating three-dimensional nanostructures on nearly any substrate with very high precision. This proposal aims to establish a nanoscale EBIDA facility by integrating a specialized nanolithography attachment with an existing state-of-the-art 1nm resolution high current variable pressure scanning electron microscope. This combination of instrumentation will enable the high-speed production of conductive and insulating structures with 1-to-10nm dimensions. The unique facility will be used to manufacture and prototype novel nanoscale devices and structures and will enable measurement of their physical and chemical properties.Read moreRead less
The Mechanics of Nanoscale Devices. Australian developments in biosensing, medical diagnostics, clean energy, communication and security technologies, are rapidly growing due to our mounting capacity in nanoscale fabrication. Vital for evolution of next-generation nanodevices is an understanding of how mechanical processes operate at such small scales. This application will contribute to this scientific knowledge base. This will in turn assist Australian industries to progress these applications ....The Mechanics of Nanoscale Devices. Australian developments in biosensing, medical diagnostics, clean energy, communication and security technologies, are rapidly growing due to our mounting capacity in nanoscale fabrication. Vital for evolution of next-generation nanodevices is an understanding of how mechanical processes operate at such small scales. This application will contribute to this scientific knowledge base. This will in turn assist Australian industries to progress these applications and devices, leading to economic, social and technological gains for the Australian community.Read moreRead less