Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100121
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Three-dimensional super-resolution nanophotonic fabrication facility. This stimulated emission depletion microscopy nanophotonic fabrication facility will be the first nanophotonic fabrication facility that is able to achieve optical resolution far beyond the diffraction limit, which will facilitate breakthroughs in cutting-edge nanotechnology research areas.
Background-free imaging of single membrane-receptors with nanophosphors. This project aims to develop nanophosphor beacons and real-time, ultrahigh-sensitivity functional imaging to provide a picture of the brain. Time-gated detection microscopy will give these nanophosphors a superior optical contrast. The nanophosphors’ antibody-targeting will image single AMPA membrane receptors in their full biological context, crucial to understanding neuronal signalling. Simultaneous imaging of receptor tr ....Background-free imaging of single membrane-receptors with nanophosphors. This project aims to develop nanophosphor beacons and real-time, ultrahigh-sensitivity functional imaging to provide a picture of the brain. Time-gated detection microscopy will give these nanophosphors a superior optical contrast. The nanophosphors’ antibody-targeting will image single AMPA membrane receptors in their full biological context, crucial to understanding neuronal signalling. Simultaneous imaging of receptor trafficking and activity in neurons will help to uncover details of the dynamic activity in the brain. This technology is expected to help understand the inner workings of the brain and provide insights into its functioning.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100074
Funder
Australian Research Council
Funding Amount
$418,210.00
Summary
Nanoscale laser cooling in physiological environment. By developing fluorescence pattern-based 3D motion-detection technology in optical tweezers, this project aims to reveal how to achieve nanoscale laser cooling in physiological media. It plans to discover new mechanisms of cooling associated with surface phonons and energy looping in optically trapped lanthanide-doped nanoparticles. Key expected outcomes are technology and a toolset to create interaction between cooled nanoscale objects and b ....Nanoscale laser cooling in physiological environment. By developing fluorescence pattern-based 3D motion-detection technology in optical tweezers, this project aims to reveal how to achieve nanoscale laser cooling in physiological media. It plans to discover new mechanisms of cooling associated with surface phonons and energy looping in optically trapped lanthanide-doped nanoparticles. Key expected outcomes are technology and a toolset to create interaction between cooled nanoscale objects and biological samples. These are expected to create a research area of biological laser refrigeration, enabling intracellular organelles cooling, nanoscale membrane disruption and high sensitivity force-sensing for integrin study for use in single-molecule biophysics and multimodality subcellular sensing.Read moreRead less
Super-resolution imaging techniques based on van der Waals materials. This project aims to address the most pressing challenges in the field of super-resolution fluorescence nanoscopies, which underpin a vast range of biomedical imaging and sensing applications. The project will develop fluorescent probes and new imaging schemes that are simultaneously ultra-bright, photostable, biocompatible and do not require the use of high-power lasers that damage samples during image acquisition. This will ....Super-resolution imaging techniques based on van der Waals materials. This project aims to address the most pressing challenges in the field of super-resolution fluorescence nanoscopies, which underpin a vast range of biomedical imaging and sensing applications. The project will develop fluorescent probes and new imaging schemes that are simultaneously ultra-bright, photostable, biocompatible and do not require the use of high-power lasers that damage samples during image acquisition. This will be achieved by exploiting unique properties of recently-discovered quantum emitters in van der Waals nanomaterials. The project outcomes will yield a new approach to super-resolution imaging, advance understanding of quantum emitters, and develop new techniques for the processing of van der Waals materials. This is expected to have applications in a diverse range of sectors, and enable new markets in nanotechnology and manufacturing of high-performance Australian-made products.Read moreRead less
Nonlinear near-field nanophotonics. This project aims to develop nanostructures which employ both high intrinsic nonlinearities and high indices of refraction to create nanophotonic devices. Silicon photonics promises a technological leap forward through efficient photon-photon interactions within lossless dielectric nanoparticles. Light-controlling-light devices open new ways to control light-matter interaction at the nanoscale, which form the basis for many applications from all-optical inform ....Nonlinear near-field nanophotonics. This project aims to develop nanostructures which employ both high intrinsic nonlinearities and high indices of refraction to create nanophotonic devices. Silicon photonics promises a technological leap forward through efficient photon-photon interactions within lossless dielectric nanoparticles. Light-controlling-light devices open new ways to control light-matter interaction at the nanoscale, which form the basis for many applications from all-optical information processing to biomedical sensing. The expected outcomes will provide Australia with advanced technologies of integrated optical circuits with applications in optical communication networks, bioimaging, solar cells and quantum information technologies.Read moreRead less
Dual nanoparticles to distinguish between right and left biomolecules. This project aims to enhance the sensitivity of optical activity to ultralow molecular concentration samples. Optical activity is a commercially available technique used to distinguish chemically identical and morphologically different biomolecules (enantiomers). Unlike other scattering techniques, near-field enhancing of optical activity has not been achieved, thus limiting these measurements to high molecular concentrations ....Dual nanoparticles to distinguish between right and left biomolecules. This project aims to enhance the sensitivity of optical activity to ultralow molecular concentration samples. Optical activity is a commercially available technique used to distinguish chemically identical and morphologically different biomolecules (enantiomers). Unlike other scattering techniques, near-field enhancing of optical activity has not been achieved, thus limiting these measurements to high molecular concentrations. There is evidence indicating that optical activity can be enhanced using dual nanoparticles (ie small particles with the same response to electric and magnetic fields). This project aims to advance our understanding of these dual nanoparticles and experimentally implement their use to enhance optical activity.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100048
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Nanoscale optical microscopy facility. The optical microscope has enabled us to see micro-objects, leading to revolutionary discoveries in medicine and natural sciences. However, the smallest object resolved by a microscope is limited by the wavelength of light. To see nanoscale objects smaller than the wavelength, a new tool for nano-imaging is needed. This project will establish a nanoscale optical microscopy facility that will reveal the topology and true colours of the nano-objects. Such inf ....Nanoscale optical microscopy facility. The optical microscope has enabled us to see micro-objects, leading to revolutionary discoveries in medicine and natural sciences. However, the smallest object resolved by a microscope is limited by the wavelength of light. To see nanoscale objects smaller than the wavelength, a new tool for nano-imaging is needed. This project will establish a nanoscale optical microscopy facility that will reveal the topology and true colours of the nano-objects. Such information, achieved through spectroscopic analysis of the light emitted or scattered at the nanoscale, will uncover some of the most fundamental aspects of the nanoworld, leading to cutting-edge scientific discoveries and important industrial applications in photonics and solar energy.Read moreRead less
Hybrid plasmonic waveguide for integrated photonic signal processing. Fast processing of information is central to modern society. This task is traditionally carried out by electronics, which however is becoming too slow and energy-consuming for some tasks. Among alternative technologies optics is the most promising, because it is fast and potentially energy efficient, but possible optical solutions are either quite bulky or suffer from high ohmic losses because the light needs to travel through ....Hybrid plasmonic waveguide for integrated photonic signal processing. Fast processing of information is central to modern society. This task is traditionally carried out by electronics, which however is becoming too slow and energy-consuming for some tasks. Among alternative technologies optics is the most promising, because it is fast and potentially energy efficient, but possible optical solutions are either quite bulky or suffer from high ohmic losses because the light needs to travel through metal. This project aims to design and fabricate a device which emits a train of short pulses, a key requirement for any signal processing, and in which the light resides mostly in low-loss material. By using metals merely to confine the light, such a 'hybrid' device would avoid the drawbacks of traditional photonic solutions.Read moreRead less
Room temperature single photon emitters in atomically thin materials. This project aims to address deterministic engineering of individual fluorescent defects in a single monolayer. This is a pressing challenge in the production of two dimensional materials as candidates for new generation devices in nanophotonics and in nanophotonics and nanoelectronics. This project will employ atomically thin, two dimensional materials to develop a platform for room temperature
devices that generate single ph ....Room temperature single photon emitters in atomically thin materials. This project aims to address deterministic engineering of individual fluorescent defects in a single monolayer. This is a pressing challenge in the production of two dimensional materials as candidates for new generation devices in nanophotonics and in nanophotonics and nanoelectronics. This project will employ atomically thin, two dimensional materials to develop a platform for room temperature
devices that generate single photons on demand. The project will provide significant benefits, such as enabling new commercial markets in nanotechnology, quantum technologies, cryptography and cybersecurity.
nanoelectronics. This project will employ atomically thin, two dimensional materials to develop a platform for room temperature devices that generate single photons on demand. The project will provide significant benefits, such as enabling new commercial markets in nanotechnology, quantum technologies, cryptography and cybersecurity.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100592
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Fabrication strategies for nanophotonic devices. The project will develop novel strategies to engineer nanophotonic entities to control and guide light at the nanoscale. These nanostructures will open up new avenues for integrated multifunctional devices spanning sensing, light emission and quantum communications, positioning Australia at the frontier of nanoscience and quantum technologies.