The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commerci ....Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commercial potential and important societal benefits.Read moreRead less
Transplantation of pancreatic islets is the only cure for type 1 diabetes (T1D). Unfortunately, many of the transplanted islet cells die quickly due to an inadequate supply of blood. Herein, we investigate a novel cell surface protein for its role in islet and blood vessel survival and function. Furthermore, we use nanotechnology to provide said protein to the islet cells during transplantation for increased survival and function. Ultimately, this work may cure more patients with diabetes.
High performance conductive mesoporous carbon electrodes: a low energy desalination alternative. The high cost of existing desalination technology has limited its wider application. There is an urgent need for alternatives which require less energy than current methods. The proposed electrosorption process utilising porous carbon electrodes has the advantage of very low energy demand. Electrosorption therefore has the opportunity to become an alternative desalination option for application in a ....High performance conductive mesoporous carbon electrodes: a low energy desalination alternative. The high cost of existing desalination technology has limited its wider application. There is an urgent need for alternatives which require less energy than current methods. The proposed electrosorption process utilising porous carbon electrodes has the advantage of very low energy demand. Electrosorption therefore has the opportunity to become an alternative desalination option for application in a national and global water desalination market. Advancement in water desalination technology has the potential for a profound social, economical and environmental impact. This vital research is aligned with the National Research Priority 1, An Environmentally Sustainable Australia; Priority Goal: Water, A critical resource.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560705
Funder
Australian Research Council
Funding Amount
$825,000.00
Summary
Advanced Deformation Simulation Laboratory. For Australia to maintain its position as a world leader in the science of metals processing it must have the capability for state-of-the-art physical simulation. The present proposal is for the purchase and installation of two leading edge simulation tools: a high rate/short inter-pass hot deformation simulator and a hot equal channel angular extrusion press. Advanced hot deformation simulation is required for the development and optimisation of "fast ....Advanced Deformation Simulation Laboratory. For Australia to maintain its position as a world leader in the science of metals processing it must have the capability for state-of-the-art physical simulation. The present proposal is for the purchase and installation of two leading edge simulation tools: a high rate/short inter-pass hot deformation simulator and a hot equal channel angular extrusion press. Advanced hot deformation simulation is required for the development and optimisation of "fast" industrial processes and for understanding the complex microstructural reactions associated with them. High temperature extrusion is required for the development of ultra-fine and nano-grained light metals.Read moreRead less
Unravelling mechanisms in plasma growth of polymers. Surface engineering broadens the breadth of applications for many materials, and enhances the performance and value of current and emerging technologies. Surface engineering is particularly important to maintaining the competitiveness of manufacturing in developed economies such as Australia, that can not compete on a cost basis with emerging economies. Plasma coating replaces (alternative) environmentally-questionable surface treatments. This ....Unravelling mechanisms in plasma growth of polymers. Surface engineering broadens the breadth of applications for many materials, and enhances the performance and value of current and emerging technologies. Surface engineering is particularly important to maintaining the competitiveness of manufacturing in developed economies such as Australia, that can not compete on a cost basis with emerging economies. Plasma coating replaces (alternative) environmentally-questionable surface treatments. This project enhances Australian competitiveness; it cuts across industrial sectors and will deliver the new knowledge required to enhance material/technology functionality/performance. A PhD student will receive a multi-disciplinary training in a frontier technology and advanced analytical tools.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH150100003
Funder
Australian Research Council
Funding Amount
$2,611,346.00
Summary
ARC Research Hub for Graphene Enabled Industry Transformation. ARC Research Hub for Graphene Enabled Industry Transformation. This research hub aims to provide the advanced materials industry with innovative solutions to tackle critical and complex challenges of national significance. The hub intends to leverage substantial existing and new investments to overcome fundamental scientific barriers and develop fit-for-purpose graphene products with and for its partners. Advanced materials, particul ....ARC Research Hub for Graphene Enabled Industry Transformation. ARC Research Hub for Graphene Enabled Industry Transformation. This research hub aims to provide the advanced materials industry with innovative solutions to tackle critical and complex challenges of national significance. The hub intends to leverage substantial existing and new investments to overcome fundamental scientific barriers and develop fit-for-purpose graphene products with and for its partners. Advanced materials, particularly graphene, are now considered promising for maintaining competitive advantages for industrial transformational progress; and advanced industries to drive prosperity where innovation underpins business to thrive globally. The anticipated impacts are long-term economic prosperity and growth.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100025
Funder
Australian Research Council
Funding Amount
$4,379,165.00
Summary
ARC Research Hub for Advanced Manufacturing with 2D Materials (AM2D). Australia holds large resources of critical 2D minerals – key enablers of several existing and emerging technologies in Energy Storage, Purification and Printed Electronics. The AM2D hub aims to provide a sophisticated environment for researchers and an industrial translation platform for manufacturers; a hub where leading academics, bright students, and industry partners come together to learn, apply, collaborate, innovate, a ....ARC Research Hub for Advanced Manufacturing with 2D Materials (AM2D). Australia holds large resources of critical 2D minerals – key enablers of several existing and emerging technologies in Energy Storage, Purification and Printed Electronics. The AM2D hub aims to provide a sophisticated environment for researchers and an industrial translation platform for manufacturers; a hub where leading academics, bright students, and industry partners come together to learn, apply, collaborate, innovate, and deliver industry transformation in advanced manufacturing. Anticipated outcomes include the transformation of newly discovered materials into globally traded, high-value 2D products, enabling Australian industries to capture more wealth and jobs from this large and growing market.
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