Toll Like Receptor signalling as a mediator of sex differences in pain, opioid and alcohol action. Brain immunology will be examined in this project to see if the signalling of a receptor called Toll Like Receptor 4 can explain sex differences in pain, and the action of pain killers and alcohol. These findings will have significant implications on the understanding of male and female brains, and will assist in the design of new drugs to treat brain and spinal cord diseases.
Cluster hardening of metastable steel alloys produced by thin strip casting. The goal of this project is to generate sufficient knowledge to apply strip casting to a wider range of steel grades and reduce the global energy cost of steel sheet production. Over 1 billion tonnes of steel is produced every year. Direct strip casting is an emerging green technology that reduces the energy required to process liquid steel into thin sheet product by up to 90 per cent. This study plans to use advanced a ....Cluster hardening of metastable steel alloys produced by thin strip casting. The goal of this project is to generate sufficient knowledge to apply strip casting to a wider range of steel grades and reduce the global energy cost of steel sheet production. Over 1 billion tonnes of steel is produced every year. Direct strip casting is an emerging green technology that reduces the energy required to process liquid steel into thin sheet product by up to 90 per cent. This study plans to use advanced atomic-scale characterisation techniques such as atom probe tomography and high-resolution electron microscopy to understand the non-equilibrium microstructures that develop as a result of the extremely rapid cooling rates experienced during strip casting.Read moreRead less