Epilepsy is a very common and serious brain disorder. Epilepsy often includes other disabilities, reduction in quality of life and is associated with increased risk of early death. 30% of people with epilepsy are unable to gain control of their seizures with currently available medications. The genetic causes of the large majority of epilepsy cases have not yet been found. This project aims to identify new genetic causes of epilepsy and its related disorders.
Investigation Of Dysfunction Of OPRS1, A Novel Gene Implicated In Neurodegeneration
Funder
National Health and Medical Research Council
Funding Amount
$535,471.00
Summary
A new gene has recently been discovered to play an important role in various brain and nerve degeneration disorders, including frontotemporal dementia and motor neuron disease. The aim of this project is to discover what biological processes are involved when this gene malfunctions, as this will provide knowledge important for development of new treatments for the many people worldwide affected with these disorders.