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The Australian Peritoneal Dialysis Outcomes And Practice Patterns Study (PDOPPS)
Funder
National Health and Medical Research Council
Funding Amount
$489,749.00
Summary
Peritoneal dialysis (PD) is a form of home dialysis that is both substantially cheaper and associated with better early survival than standard hospital-based haemodialysis. Its use in Australia has been severely limited by poor outcomes compared to the rest of the world. This international study aims to identify “real world” PD centre practices that will lead to better outcomes for Australian patients, greater uptake of home dialysis and health savings of tens of millions of dollars annually.
A Novel Diabetic Retinopathy Screening Model Based On Pathology Services (Ret-Path) For People With Diabetes.
Funder
National Health and Medical Research Council
Funding Amount
$764,273.00
Summary
Most vision loss from diabetic retinopathy, a severe complication of diabetes, can be prevented by early detection. However, with no recognized eye screening procedure, up to half of Australians with diabetes do not have a regular eye check. We have successfully piloted a new eye screening model using pathology centres as an opportunistic catchment point. In this project, we will demonstrate the overall effectiveness and economic benefits of this novel eye screening model in urban and rural Vict ....Most vision loss from diabetic retinopathy, a severe complication of diabetes, can be prevented by early detection. However, with no recognized eye screening procedure, up to half of Australians with diabetes do not have a regular eye check. We have successfully piloted a new eye screening model using pathology centres as an opportunistic catchment point. In this project, we will demonstrate the overall effectiveness and economic benefits of this novel eye screening model in urban and rural Victoria for people with diabtetes.Read moreRead less
A Multi-centre RCT Of An Open Lung Strategy Including Permissive Hypercapnia, Alveloar Recruitment, And Low Airway Pressure In Patients With ARDS
Funder
National Health and Medical Research Council
Funding Amount
$1,041,070.00
Summary
Acute respiratory distress syndrome (ARDS) is a severe inflammatory condition of the lungs that complicates many critical illnesses and is associated with high mortality. Inappropriate settings of the mechanical ventilator can lead to a worsening outcome. The aim of this Phase II study is to compare the clinical efficiency of a novel ventilation strategy to reduce the duration of mechanical ventilation in survivors, including several lung protective settings, to that of current standard care.
Comparing The Effectiveness Of Selective Laser Trabeculoplasty With Topical Medication For The Treatment Of Primary Angle Closure Glaucoma: A Multicentred, Prospective, Randomized Controlled Clinical Trial.
Funder
National Health and Medical Research Council
Funding Amount
$639,888.00
Summary
The main treatment of glaucoma, an eye condition which causes peripheral vision loss and blindness, involves the use of eye drops. However, these are expensive, have considerable side effects, and impact negatively on daily living. Laser has recently been proposed as an alternative treatment and, in this project, we will investigate the effectiveness of laser compared to medication. We anticipate laser will be more cost effective, safer, and have a positive impact on quality of life compared to ....The main treatment of glaucoma, an eye condition which causes peripheral vision loss and blindness, involves the use of eye drops. However, these are expensive, have considerable side effects, and impact negatively on daily living. Laser has recently been proposed as an alternative treatment and, in this project, we will investigate the effectiveness of laser compared to medication. We anticipate laser will be more cost effective, safer, and have a positive impact on quality of life compared to eye drops.Read moreRead less
Falls Prevention In The Acute Hospital Setting: A Multi-centre Cluster Randomised Controlled Trial Of Efficacy, Cost Effectiveness And Sustainability Of The 6-PACK Program.
Funder
National Health and Medical Research Council
Funding Amount
$1,218,771.00
Summary
Older people commonly fall in hospital suffering injuries such as a broken hip which are costly for the faller and hospital. Falls can result in a nursing home stay as they reduce a person's confidence and ability to do simple tasks like showering. We have designed a program with the potential to reduce fall injuries, using an approach with promising results from one hospital. This project will evaluate this program that aims to improve the care of older people in hospital.
The RINSE Trial: The Rapid Infusion Of Cold Normal SalinE By Paramedics During CPR
Funder
National Health and Medical Research Council
Funding Amount
$708,241.00
Summary
Sudden cardiac arrest is a common event in the community. Therapeutic hypothermia decreases the brain injury caused by the cardiac arrest and is currently used in the hospital after successful resuscitation. However, there may be better outcomes if the brain is cooled by paramedics during resuscitation. We will compare survival rates for those patients cooled early by paramedics using an infusion of ice-saline during cardiac arrest with those patients who are later cooled by the hospital.
A Randomized Controlled Trial Of Three Treatments For Anorexia Nervosa In Adults
Funder
National Health and Medical Research Council
Funding Amount
$606,447.00
Summary
This study will be the first to evaluate three promising new treatments for anorexia nervosa (AN) and anorexic type eating disorders in adults. The first treatment is a new therapy called Enhanced Cognitive Behaviour Therapy. The second treatment, the Maudsley Cognitive Motivational Therapy, was designed specifically to treat AN and the third treatment is called non-specific supportive clinical management. The study will be in the form of a multi-centre randomised treatment trial.