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In spite of significant progress, inflammatory diseases remain poorly understood and difficult to treat and are of growing public health importance. This fellowship application is for translational research on improving treatment for inflammatory diseases, including rheumatoid arthritis. It will link the senior clinical appointments of Prof Ian Wicks in Rheumatology at the Royal Melbourne Hospital with his appointment as Head of the Inflammation Division at the Walter & Eliza Hall Institute of M ....In spite of significant progress, inflammatory diseases remain poorly understood and difficult to treat and are of growing public health importance. This fellowship application is for translational research on improving treatment for inflammatory diseases, including rheumatoid arthritis. It will link the senior clinical appointments of Prof Ian Wicks in Rheumatology at the Royal Melbourne Hospital with his appointment as Head of the Inflammation Division at the Walter & Eliza Hall Institute of Medical Research.Read moreRead less
I am a practising hospital physician and a trained scientist and am widely acknowledged at the world leader in my field of study, asbestos cancers. Our latest research discoveries have put us on the threshold of bold new approaches to curing the scourge of these cancers and finding better blood tests but this work now requires extra attention from me to bring it to fruition. A Practitioner Fellowship is an ideal way for me to continue to lead this exciting research.
The Future Of HIV Care - Long Term Remission And Eliminating Co-morbidities
Funder
National Health and Medical Research Council
Funding Amount
$577,189.00
Summary
Despite the great successes in antiretroviral therapy (ART) in reducing HIV-associated mortality, treatment is life long and there is no cure. The major barrier to a cure for HIV is the persistence of long lived latently infected cells on ART. Over the next five years I will discover, develop, optimise and evaluate novel interventions to eliminate latently infected cells, long lived infected cells in the liver and enhance HIV-specific immunity through immunotherapy.
Modulation Of Cytokine Responses To Improve Transplant Outcome.
Funder
National Health and Medical Research Council
Funding Amount
$26,186.00
Summary
Bone marrow transplantation remains a mainstay of curative therapy for haematological malignancies. This curative effect is mediated by the transplanted donor immune system which rejects the recipient malignancy. However, the procedure is limited by its serious side effect, known as graft-versus-host disease. This application seeks to better understand these two processes at both an immunological and clinical level with the aim of separating the two so that more patients may be cured of leukaemi ....Bone marrow transplantation remains a mainstay of curative therapy for haematological malignancies. This curative effect is mediated by the transplanted donor immune system which rejects the recipient malignancy. However, the procedure is limited by its serious side effect, known as graft-versus-host disease. This application seeks to better understand these two processes at both an immunological and clinical level with the aim of separating the two so that more patients may be cured of leukaemia.Read moreRead less