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New insulins for the improved management of diabetes. The prevalence of diabetes has increased dramatically over the past few decades and now this condition is widely considered the world’s fastest growing disease. New insulins with improved pharmacological and storage properties are desperately needed, and this project will work on chemical synthesis enabling designer insulins to be prepared for improved management of diabetes.
Nobody knows anything? Applying pari-mutuel prediction markets to the motion picture industry. This project will explore the predictability of unreleased motion pictures' theatrical box office revenues using incentive rich pari-mutuel prediction markets. The mechanism will promote price discovery and associated probability estimates that will benefit those already investing in the industry as well as encouraging new investment.
Mechanisms and modelling of gels for protein separation. Gradipore approached Sydney University to collaborate on fundamental science needed to improve polymer gels for separation and characterization of proteins. These gels have many applications: e.g. proteomics and diagnostics. Presently, control of polymer microstructure in the synthesis of these gels is by trial and error. This project will create an accurate model of the process so pore size can be predicted. This involves novel work in ex ....Mechanisms and modelling of gels for protein separation. Gradipore approached Sydney University to collaborate on fundamental science needed to improve polymer gels for separation and characterization of proteins. These gels have many applications: e.g. proteomics and diagnostics. Presently, control of polymer microstructure in the synthesis of these gels is by trial and error. This project will create an accurate model of the process so pore size can be predicted. This involves novel work in experimental and theoretical methods developed by the Sydney University group. The result will be qualitative and quantitative understanding which can be subsequently used to tailor-make gels for new applications.Read moreRead less
Computational methods in atomic collision theory. We will develop computational methods for solving interactions between particles on the atomic scale. Computational problems, of particular interest to the industry partner, are the treatment of large-scale ill-conditioned linear systems, and the extension of the Gaussian molecular structure package to collision physics. We have been world-leaders in the field of atomic collision theory for almost a decade, and now, utilising the latest software ....Computational methods in atomic collision theory. We will develop computational methods for solving interactions between particles on the atomic scale. Computational problems, of particular interest to the industry partner, are the treatment of large-scale ill-conditioned linear systems, and the extension of the Gaussian molecular structure package to collision physics. We have been world-leaders in the field of atomic collision theory for almost a decade, and now, utilising the latest software and hardware, will have the capacity to extend the numerical techniques to a vast range of collision systems of interest to science and industry, where visualisation and sheer computer power will play a major role in both
code development and production runs.Read moreRead less
Why is ColorbondR steel greener on the other side of the fence? Designing additives to retard weathering of surface coatings. COLORBONDR steel, the flagship pre-painted steel product of BlueScope Steel Limited, has become an iconic part of both suburban and outback landscapes whether installed as roofing, walling or water conservation accessories (tanks, down-pipes etc). This proposal aims to provide a detailed understanding of molecular level changes in COLORBONDR steel surface coatings brought ....Why is ColorbondR steel greener on the other side of the fence? Designing additives to retard weathering of surface coatings. COLORBONDR steel, the flagship pre-painted steel product of BlueScope Steel Limited, has become an iconic part of both suburban and outback landscapes whether installed as roofing, walling or water conservation accessories (tanks, down-pipes etc). This proposal aims to provide a detailed understanding of molecular level changes in COLORBONDR steel surface coatings brought about by levels of heat and radiation encountered in-service. These insights will lead to further improvements in both lifetime and aesthetic durability of COLORBONDR steel, ensuring continuing economic success of BlueScope in the domestic building market with consequent benefits to manufacturing communities throughout the supply-chain nationwide.Read moreRead less
Development of Dry Coated Pigment Particles: Durability and Dispersion. Tiwest is the only business in the world that mines, separates, refines and manufactures titanium dioxide products in one region. Tiwest has a major impact on the Western Australian economy with more than 700 full time and contract jobs, export earnings of $400M (in 2004) and regular incomes for an estimated 500 businesses. The current wet pigment particle coating process, to ensure ease of handling and longevity, is a major ....Development of Dry Coated Pigment Particles: Durability and Dispersion. Tiwest is the only business in the world that mines, separates, refines and manufactures titanium dioxide products in one region. Tiwest has a major impact on the Western Australian economy with more than 700 full time and contract jobs, export earnings of $400M (in 2004) and regular incomes for an estimated 500 businesses. The current wet pigment particle coating process, to ensure ease of handling and longevity, is a major cost. An optimised pigment dry-coating process would ensure Tiwest's competitiveness through reduced processing costs and improved performance. This development has the potential to increase Tiwest's profitability by 10%.Read moreRead less
Reduction of risk in exploration for petroleum liquids. Australia has an urgent need to establish additional reserves of crude oil. A feature of petroleum exploration in recent decades has been discovery of vast reserves of natural gas but an inability to replace our diminishing reserves of crude oil. Clearly new technology is required to enhance our capability to recognise crude oil-prone rather than gas-prone source rocks. The proposed project will establish the fundamental geochemical pro ....Reduction of risk in exploration for petroleum liquids. Australia has an urgent need to establish additional reserves of crude oil. A feature of petroleum exploration in recent decades has been discovery of vast reserves of natural gas but an inability to replace our diminishing reserves of crude oil. Clearly new technology is required to enhance our capability to recognise crude oil-prone rather than gas-prone source rocks. The proposed project will establish the fundamental geochemical processes that will support the potential exploration techniques, developed with Woodside Energy Limited support.Read moreRead less
Manipulating the self-assembly properties of fungal hydrophobin proteins for the design of novel biological polymers. Hydrophobin-based products will be novel biocompatible and biodegradable products with applications in the fields of medical implants, biosensors, detergents, coatings and pharmaceutical and industrial emulsions. They have the potential to directly improve the lives of all Australians and to be of benefit to the Australian economy and environment. This collaborative research pro ....Manipulating the self-assembly properties of fungal hydrophobin proteins for the design of novel biological polymers. Hydrophobin-based products will be novel biocompatible and biodegradable products with applications in the fields of medical implants, biosensors, detergents, coatings and pharmaceutical and industrial emulsions. They have the potential to directly improve the lives of all Australians and to be of benefit to the Australian economy and environment. This collaborative research project will enable Australian scientists to gain from working with a multinational company and to acquire skills in the rapidly expanding fields of structural and molecular biology. The University of Sydney will own any intellectual property arising from this work and will benefit from the commercialisation of hydrophobin-based products.Read moreRead less
Highly Crosslinked Poly(urea-co-urethane) Copolymer Concrete Floor Coatings. Recently developed, poly(urea-co-urethane) concrete floor screeds are used, in the construction industry, to provide protection against corrosive chemicals and abrasive wear; properties unmatched by other commercial floor treatments. Significantly such material has reduced environmental emissions and toxicity hazards. Factors, which affect the cure and performance of poly(urea-co-urethane) flooring materials will now ....Highly Crosslinked Poly(urea-co-urethane) Copolymer Concrete Floor Coatings. Recently developed, poly(urea-co-urethane) concrete floor screeds are used, in the construction industry, to provide protection against corrosive chemicals and abrasive wear; properties unmatched by other commercial floor treatments. Significantly such material has reduced environmental emissions and toxicity hazards. Factors, which affect the cure and performance of poly(urea-co-urethane) flooring materials will now be studied, including the uncontrolled release of carbon dioxide, which results in sporadic blister formation, leading to the on-site product failures that have severely limited the product's commercial growth. Clear understanding of cure chemistry and adhesion will be established for the first, allowing for the products further development.Read moreRead less
The Nanotechnology Desalination Research Project - Low Energy Desalination Membranes. Population growth and global warming is rapidly increasing the strain placed on fresh water supplies. Environmentally sustainable solutions to this water shortage need to be found urgently. This project will develop new, low energy desalination technologies which can be powered by renewable energy sources, to enable desalination to be widely applied with low environmental impacts. It addresses several national ....The Nanotechnology Desalination Research Project - Low Energy Desalination Membranes. Population growth and global warming is rapidly increasing the strain placed on fresh water supplies. Environmentally sustainable solutions to this water shortage need to be found urgently. This project will develop new, low energy desalination technologies which can be powered by renewable energy sources, to enable desalination to be widely applied with low environmental impacts. It addresses several national priorities: Water - a critical resource; Transforming existing industries; Overcoming soil loss, salinity and acidity; Responding to climate change and variability; Frontier technologies and Advanced materials.Read moreRead less