Single spin molecular microscope. This project aims to create a new tool for imaging and analysing material at the atomic level. The tool is based on individual quantum coherent spins in diamond which can be manipulated and optically read. The project expects to generate knowledge in quantum metrology and an understanding of molecular dynamics at the nanoscale. The expected outcome is a new type of device capable of imaging complex physical systems at the level of their individual constituent co ....Single spin molecular microscope. This project aims to create a new tool for imaging and analysing material at the atomic level. The tool is based on individual quantum coherent spins in diamond which can be manipulated and optically read. The project expects to generate knowledge in quantum metrology and an understanding of molecular dynamics at the nanoscale. The expected outcome is a new type of device capable of imaging complex physical systems at the level of their individual constituent components. This has significant benefits in improving designer materials, energy production, information storage, and drug design.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less