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A high-through-put method for unlocking the mitochondrial genomes of significant pathogens. The national/community benefits of this research are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to ....A high-through-put method for unlocking the mitochondrial genomes of significant pathogens. The national/community benefits of this research are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by promoting collaborative research, resulting in a more efficient use of resources in a national and international context; (4) to enhance the skills-base in biology and biotechnology; and (5) to substantially increase global visibility through quality research, leading to an increased investment in Australian science.Read moreRead less
Evolution of the biofabrication of mineralized structures in animals. Shells and skeletons are produced by a wide range of animals. These highly-order crystalline structures are genetically-encoded and produce high-performance composite materials that exceed present capabilities in human engineering. This international collaboration will elucidate the molecular mechanisms controlling the fabrication of these architectures. This knowledge will contribute significantly to the development of materi ....Evolution of the biofabrication of mineralized structures in animals. Shells and skeletons are produced by a wide range of animals. These highly-order crystalline structures are genetically-encoded and produce high-performance composite materials that exceed present capabilities in human engineering. This international collaboration will elucidate the molecular mechanisms controlling the fabrication of these architectures. This knowledge will contribute significantly to the development of materials for advanced electronics and energy transducers, human bone therapeutics and marine-based products such as pearls and cements, through the identification of genes underlying biofabrication networks and the development of in vitro bioproduction systems.Read moreRead less
Echoes of the earliest Homo sapiens movement out of Africa. The "Out of Africa" and "Multiregional Evolution" theories have proposed sharply different accounts for the origins of our species Homo sapiens. These have converged on opposite readings of the Australian human fossil record. Recent perspectives resulting from research on Pleistocene Australian mitochondrial DNA, and by osteologists on early Homo sapiens remains in Africa and Israel, hint at a chapter, as yet unwritten, in our species' ....Echoes of the earliest Homo sapiens movement out of Africa. The "Out of Africa" and "Multiregional Evolution" theories have proposed sharply different accounts for the origins of our species Homo sapiens. These have converged on opposite readings of the Australian human fossil record. Recent perspectives resulting from research on Pleistocene Australian mitochondrial DNA, and by osteologists on early Homo sapiens remains in Africa and Israel, hint at a chapter, as yet unwritten, in our species' Late Pleistocene dispersal from Africa. This project's collaborative research on fossils from Sri Lanka and Australasia will explore and test the implications for the colonisation history of the Indian Ocean region.Read moreRead less
MitoGenomics of Key Pathogens - An International Research Co-operative. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by pr ....MitoGenomics of Key Pathogens - An International Research Co-operative. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by promoting collaborative research, resulting in a more efficient use of resources in a national and international context; (4) to enhance the skills-base in biology and biotechnology; (5) to substantially increase global visibility through quality research, leading to an increased investment in Australian science.Read moreRead less
Insect host/vector genetic responses to rhabdovirus infection. Rhabdoviruses cause important diseases in humans, animals and plants. These viruses are transmitted by insect vectors in which they persist and propagate, an intimate and specific association. Insect-rhabdovirus interactions will be studied at the molecular level using a planthopper-maize rhabdovirus model. Insect genes specifically induced by rhabdovirus infection as well as the viral genes themselves will be identified and characte ....Insect host/vector genetic responses to rhabdovirus infection. Rhabdoviruses cause important diseases in humans, animals and plants. These viruses are transmitted by insect vectors in which they persist and propagate, an intimate and specific association. Insect-rhabdovirus interactions will be studied at the molecular level using a planthopper-maize rhabdovirus model. Insect genes specifically induced by rhabdovirus infection as well as the viral genes themselves will be identified and characterized using genomics and bioinformatics tools. We will extend the same approaches to a comparative analysis of these planthopper genes with other insect-rhabdovirus systems under investigation in our institutes. Identification of viral genes expressed in insects, the insect genes that respond to virus infection, and interpretation of the roles of these genes in insects, may indicate new opportunities to control serious plant and animal diseases through control of virus transmission.Read moreRead less
Adaptive evolution of mutual mate preferences in nature. Working at the interface of evolution, genetics and the environment, our research combines top scientists from Australia and abroad to seek a comprehensive understanding of the origins of biodiversity, and the evolution of new species. Such knowledge is essential if we wish to predict, and hopefully minimise, the loss of biodiversity through human-mediated environmental change. Using a native Australian insect, we are investigating the evo ....Adaptive evolution of mutual mate preferences in nature. Working at the interface of evolution, genetics and the environment, our research combines top scientists from Australia and abroad to seek a comprehensive understanding of the origins of biodiversity, and the evolution of new species. Such knowledge is essential if we wish to predict, and hopefully minimise, the loss of biodiversity through human-mediated environmental change. Using a native Australian insect, we are investigating the evolutionary consequences of the choice individuals make when selecting a mate. In addition to its role in the origin and maintenance of biodiversity, these choices can have fundamental effects on adaptation to changing environments and the long-term persistence of endangered populations.Read moreRead less
Investigating Near-Threshold Atomic and Molecular Collision Processes with Multiparameter Detection Techniques. We are proposing to perform state-of-the-art, electron impact excitation and ionization measurements on a range of atoms and molecules. The combination of new detector technology and innovative experimental design will enable measurements of near-threshold excitation and ionization in a number of important atomic and molecular systems. The measurements will have implications for the ....Investigating Near-Threshold Atomic and Molecular Collision Processes with Multiparameter Detection Techniques. We are proposing to perform state-of-the-art, electron impact excitation and ionization measurements on a range of atoms and molecules. The combination of new detector technology and innovative experimental design will enable measurements of near-threshold excitation and ionization in a number of important atomic and molecular systems. The measurements will have implications for the further development of atomic scattering theory, particularly the role of electron-electron correlations, and provide much needed absolute scattering information on the excitation of molecules which are of relevance to our atmosphere and various technological devices.Read moreRead less
Electronic and atomic collision theory. Recently there has been rapid progress in the field of electronic and atomic collisions. Consequently, many new problems have emerged of interest to science and industry. The proposed collaboration will determine the most promising theoretical techniques for their solution. The problems include, for example, electron
collisions with noble gases, cesium and mercury, of interest to the laser, lighting and plasma processing industries. Time-dependent and tim ....Electronic and atomic collision theory. Recently there has been rapid progress in the field of electronic and atomic collisions. Consequently, many new problems have emerged of interest to science and industry. The proposed collaboration will determine the most promising theoretical techniques for their solution. The problems include, for example, electron
collisions with noble gases, cesium and mercury, of interest to the laser, lighting and plasma processing industries. Time-dependent and time independent, relativistic and non-relativistic approaches will be considered, thereby determining the direction of the field for the foreseeable future.Read moreRead less
Multiple atomic photoionization in superstrong electromagnetic field. Correlation, or entanglement, of electrons in matter governs many important phenomena in nature, such as chemical reactions, superconductivity and ferromagnetism. However, it is the many-electron processes in atoms which allow the study of electron correlations most clearly. In this project we will investigate such a process of two-electron atomic photoionization by an intense laser pulse. We will combine advanced theoretical ....Multiple atomic photoionization in superstrong electromagnetic field. Correlation, or entanglement, of electrons in matter governs many important phenomena in nature, such as chemical reactions, superconductivity and ferromagnetism. However, it is the many-electron processes in atoms which allow the study of electron correlations most clearly. In this project we will investigate such a process of two-electron atomic photoionization by an intense laser pulse. We will combine advanced theoretical and experimental tools with the aim of understanding how the electron correlation interplays with the superstrong electromagnetic field. This will provide insight into fundamental processes of interaction of intense laser pulses with matter which are important in a wide range of applications.Read moreRead less
Studying Molecular Dynamics with Electron and Laser Interactions. We plan to use state-of-the-art experimental techniques and methodologies to probe the dynamics of molecular processes stimulated by either laser or electron interactions. These processes are fundamental to our understanding of both natural phenomena and many devices used in the technology of today and of the future. As a result of this study our insight into the mechanisms underpining these phenomena and devices will be enhanced.