From risk factor analysis to translation: multiple sclerosis and vitamin D deficiency. This research on multiple sclerosis will focus on its causes and lifestyle factors that affect it and will trial vitamin D supplementation as a treatment. Studies on vitamin D deficiency in healthy populations aim to develop new public health recommendations on sun exposure and vitamin D that balance risk of skin cancer against vitamin D deficiency.
Epidemiologic and economic approaches to reduce the burden of depression and related chronic diseases in the workforce. Employers and governments alike are increasingly recognising that mental health impacts productivity, but many employers remain uninformed about the magnitude of the productivity consequences and what they can do about it. The ongoing individual and economic burden from depressive and anxiety disorders among working adults necessitates multi-disciplinary solutions. This series ....Epidemiologic and economic approaches to reduce the burden of depression and related chronic diseases in the workforce. Employers and governments alike are increasingly recognising that mental health impacts productivity, but many employers remain uninformed about the magnitude of the productivity consequences and what they can do about it. The ongoing individual and economic burden from depressive and anxiety disorders among working adults necessitates multi-disciplinary solutions. This series of studies will provide nationally and internationally significant new data to both inform understanding of the magnitude of the problem, and to provide cost-effective solutions to addressing it. Findings will directly inform workplace mental health promotion and prevention activities and be usable by employers, clinicians, and governments.Read moreRead less
Genetics, genomics and evolution of flowering time control in legumes. Flowering in plants is strongly regulated by environmental factors, with important consequences for their natural distribution and use in agriculture. This project will characterise genes, genetic diversity and molecular mechanisms that control flowering in legumes, contributing to fundamental biology, crop improvement and research training.
Decoding the signals in legume symbioses: investigating the role of plant hormones. Plants form intimate relationships with soil microbes that give plants access to previously unavailable but essential nutrients. Legumes are major Australian crops for fodder, grain and nutrients, and are unique in forming symbioses with both nitrogen-fixing bacteria and with mycorrhizal fungi that supply nutrients such as phosphate. This project aims to determine the role of plant hormones (small, mobile, potent ....Decoding the signals in legume symbioses: investigating the role of plant hormones. Plants form intimate relationships with soil microbes that give plants access to previously unavailable but essential nutrients. Legumes are major Australian crops for fodder, grain and nutrients, and are unique in forming symbioses with both nitrogen-fixing bacteria and with mycorrhizal fungi that supply nutrients such as phosphate. This project aims to determine the role of plant hormones (small, mobile, potent growth regulators) in the formation of these relationships. In particular, the role of interactions between hormones and other novel plant signals will be determined. An insight into the common and divergent roles of hormones in these symbioses is essential to provide new tools to maximise nutrient acquisition.Read moreRead less
Tools for manipulating neuronal activity for behavioural studies. This project aims to develop optogenetic tools neuroscientists can use to better understand brain circuitry and the functional effects of specific neurons on behaviour. Linking the activity of individual neurons in the brain to specific behaviours is a major challenge in neuroscience. Optogenetics achieve this by using light to control the activity of neurons. This has advanced understanding of behaviour and neurocircuitry. This p ....Tools for manipulating neuronal activity for behavioural studies. This project aims to develop optogenetic tools neuroscientists can use to better understand brain circuitry and the functional effects of specific neurons on behaviour. Linking the activity of individual neurons in the brain to specific behaviours is a major challenge in neuroscience. Optogenetics achieve this by using light to control the activity of neurons. This has advanced understanding of behaviour and neurocircuitry. This project is expected to increase understanding of brain function at the cellular and system levels, and advance Australia’s multidisciplinary research capacity in neuroscience, cognitive sciences and nanobiotechnology to ultimately treat neurological disorders.Read moreRead less
Interpreting biological sequence information: untangling hybridisation. Hybridisation is believed to be important during adaptive radiations where species rapidly colonise new niches and respond to new environments, e.g. in times of climate change. This project will create the statistical tools and software required for evolutionary biologists to understand how hybridisation has helped shape the Australian flora.