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Accelerated Longterm Forgetting In Children With Genetic Generalised Epilepsy: An Investigation Of The Temporal Trajectory And Contribution Of Executive Skills.
Funder
National Health and Medical Research Council
Funding Amount
$107,204.00
Summary
The aim of this study is to determine which factors influence forgetting in typically developing children and in children with epilepsy. Specifically, we want to establish how forgetting occurs over time and whether it is influenced by other cognitive/thinking skills, such as strategies used to remember information, attention or resistance to interference. Moreover, we are interested in whether retention rates are affected by different types of learning materials (i.e. visual versus verbal).
Managing Depression Within Low Vision Rehabilitation Services: The Effectiveness Of Integrating An Evidence-based Therapy ‘Problem-Solving Therapy For Primary Care’ On Depression, Quality Of Life And Service Utilisation In Those With Low Vision
Funder
National Health and Medical Research Council
Funding Amount
$92,785.00
Summary
This research will evaluate the integration of an evidence-based treatment for depression into low vision rehabilitation services. It is anticipated that this new program will lead to sustained improvements in participants’ quality of life and mental health. This is the first time a system to manage depression has been implemented into low vision services worldwide and if successful this intervention could be suitable for application to other chronic health conditions.
Brain Connectivity Biomarkers Predict Specific Memory Consolidation Deficits Across Dementia Subtypes
Funder
National Health and Medical Research Council
Funding Amount
$83,149.00
Summary
With the increasing ageing population there is expected to be a significant increase in the number of dementia cases in the near future. This project aims to improve the accuracy of existing diagnostic protocols for dementia by combining recent advances in magnetic resonance imaging with traditional cognitive assessments. We expect the outcome to improve detection in the early stages of disease onset so that patients may receive immediate medical treatment.
BDNF Genotype And Emotional Memory In Post-traumatic Stress Disorder
Funder
National Health and Medical Research Council
Funding Amount
$108,902.00
Summary
This project addresses the question of why some people develop PTSD following trauma and others don’t. It will assess the influence of genetics (specifically a genotype that influences Brain Derived Neurotrophic Factor) on emotional memory processes as distressing emotional memories are a core symptom of PTSD. If we find that people with a particular genetic profile have a greater risk of developing intrusive memories after trauma, this will help us better target treatment for those individuals.
There is strong evidence of an increased falls risk associated with cataract, a primary cause of vision impairment in older Australians. This research will determine factors contributing to increases in falls risk in people aged 70 years and older with cataract before surgery, between first and second eye surgery, and after second eye surgery. The findings can inform the optimal management of older people with cataract and limit negative health impacts of cataract-related injury and falls.
Speech Pathology Intervention For Young Offenders With Language Impairment
Funder
National Health and Medical Research Council
Funding Amount
$107,182.00
Summary
Male young offenders are at high risk of undetected oral language impairments. This study will assess language impaired young offenders, and evaluate the efficacy of speech pathology intervention to improve oral language skills. The study will also evaluate whether this intervention can enhance other interventions and rehabilitation, and reduce the chances of reoffending, through the development of prosocial behaviours and characteristics.
Modifying Cognitive Trajectories Using Computerised Cognitive Training
Funder
National Health and Medical Research Council
Funding Amount
$72,768.00
Summary
The "Use it or lose it" principal is highly applicable in cognition functions, particularly with ageing. This project aims to use an intervention that promotes active brain processes and function to protect and preserve it from deterioration. The effect of this dementia-prevention strategy and results will help fill gaps in the current body of knowledge, and will allow the prescription of individualised treatment by showing the mechanisms by which this intervention works to improve cognition.
Defining An Ethical And Evidence-based Approach To Clinical Research In Children And Adolescents With Chronic Kidney Disease (CKD)
Funder
National Health and Medical Research Council
Funding Amount
$84,800.00
Summary
Chronic kidney disease (CKD) in children and adolescents is a serious health condition, which impacts patients' academic abilities and achievement as well as their social wellbeing and their physical and mental health. This study will investigate the range of impacts that CKD has on patients and families, and explore the ways that these problems should best be addressed in future research from the perspective of patients and their families.
Modern Chemical Exposures In Utero And In Infancy, And Their Impact Upon Early Neurodevelopmental Outcomes In The Barwon Infant Study, An Unselected Birth Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$138,353.00
Summary
I am a paediatric doctor interested in the effects of modern industrial chemicals on children’s development. Even in the womb babies are exposed to industrial chemicals and we know some, like lead, are harmful to developing brains. I am interested in other chemicals that are now suspected to affect development, including the polybrominated diphenyl esters (PBDEs), and I intend to investigate this as part of the Barwon Infant Study, which follows 1250 children from before birth to 3 years.
Altered Sense Of Identity In Dementia: Cognitive And Neurobiological Underpinnings
Funder
National Health and Medical Research Council
Funding Amount
$108,902.00
Summary
People with dementia commonly experience changes in their sense of identity, causing significant distress for the individual and their families. This project will investigate these changes comprehensively, determining their contributing factors and how they relate to dementia’s effect on the brain. Outcomes from this project will improve understanding of the experience of the person with dementia, informing personalised care and enhancing the quality of patient-carer relationships.