Enhancing Aspects Of Time-to-event Analysis Methodology In Randomised Trials
Funder
National Health and Medical Research Council
Funding Amount
$548,446.00
Summary
Time-to-event analysis is a statistical method for examining the occurrence of disease-related events in individuals followed for varying periods of time. The method is widely used in health research. The technicalities of the methods are subtle and by paying careful attention to these this grant will provide extended methods, new software, and apply methods more effectively to gain new insights to disease progress, and to enhance the efficiency of health research.
New Methods And Guidelines For The Design, Analysis And Reporting Of Cluster-crossover And Stepped Wedge Randomised Trials In Clinical And Public Health Research
Funder
National Health and Medical Research Council
Funding Amount
$391,258.00
Summary
Cluster crossover and stepped wedge designs have emerged recently as study designs used in clinical and public health research settings. However, despite their use there has been very little methodological assessment of the statistical analysis methods used in current practice. The proposed research will assess the correctness of current methods and will produce a toolkit of state-of-the art, defensible trial design, analysis and reporting methods for the clinical/health researcher.
Cost-effective Development And Validation Of Risk Prediction Models: Methods And Applications
Funder
National Health and Medical Research Council
Funding Amount
$157,322.00
Summary
We will develop statistical methods and software that will enable risk calculators being built and validated using study designs that require only a fraction of current cost. The methods and software will be freely-available to researchers worldwide.
The Victorian Centre For Applied Biostatistics (VCAB): Building Core Methodological Capacity For Population Health
Funder
National Health and Medical Research Council
Funding Amount
$2,497,184.00
Summary
Biostatistics is the scientific discipline that focusses on the methods used to design and analyse research studies on human health. Doctors and other researchers conduct increasingly complex studies to identify best approaches for the prevention and treatment of disease, and these studies must be underpinned by sound biostatistical methods. This Centre will develop a critical mass of expertise in this under-resourced area around a program of methodological research, translation and training.