Tuning parallel applications on software-defined supercomputers. Supercomputers are used by many Australian industries and laboratories to make better products and perform critical predictions, and it is essential that codes operate efficiently. This project aims to assist programmers in identifying performance bottlenecks in their code quickly and easily. The project expects to supersede the current methods, which are often complex and time-consuming, by developing innovative software tools and ....Tuning parallel applications on software-defined supercomputers. Supercomputers are used by many Australian industries and laboratories to make better products and perform critical predictions, and it is essential that codes operate efficiently. This project aims to assist programmers in identifying performance bottlenecks in their code quickly and easily. The project expects to supersede the current methods, which are often complex and time-consuming, by developing innovative software tools and techniques. The expected outcomes include novel software, verified by industry partners in real world case studies, ranging from life sciences to hypersonic transport. This should provide significant benefits, including the capacity for Australian industries to access world-class supercomputing technology.Read moreRead less
Investigation of a Dynamic Collaborative Framework for Multi-Modal Devices. Modern business and society increasingly call for agility through the rapid formation of groups and collaboration of individuals. Mobile computing devices have the potential to enable this collaboration. However this is currently unrealised; software is not keeping up with hardware. This project aims to investigate techniques and software tools to provide an adaptive framework for multimedia-rich applications, which seam ....Investigation of a Dynamic Collaborative Framework for Multi-Modal Devices. Modern business and society increasingly call for agility through the rapid formation of groups and collaboration of individuals. Mobile computing devices have the potential to enable this collaboration. However this is currently unrealised; software is not keeping up with hardware. This project aims to investigate techniques and software tools to provide an adaptive framework for multimedia-rich applications, which seamlessly support collaboration through multi-modal communications between heterogenous mobile devices. This combination of multimedia, smart devices and advanced communications has the potential to revolutionise many key industries by making information available and manipulable in new and better ways.Read moreRead less
Understanding concurrent programs using rely-guarantee thinking. Multi-core processors are standard in computers and devices (e.g. smart phones) but much of the software available for these machines is either unreliable or does not exploit the available hardware parallelism. This project will devise techniques for designing concurrent software that exploits these platforms while delivering dependable operation.
Software debuggers for next generation heterogeneous supercomputers. Supercomputing underpins a wide range of areas of importance to the Australian economy; mining, agriculture, engineering and medical research to name a few. It is of critical importance that software solutions in these areas behave correctly. This project will develop software tools and techniques to help locate errors in such applications.
Verified Emulation of Legacy Mission Computer Systems. Processor obsolescence is a serious maintenance problem for long-lived computer control systems in military aircraft and other critical applications. A promising solution is to interpose an emulator program between the original "legacy" software and a replacement processor. Unfortunately, no techniques exist for accurately verifying that this procedure preserves the original system's functional and timing behaviour. A particular challenge ....Verified Emulation of Legacy Mission Computer Systems. Processor obsolescence is a serious maintenance problem for long-lived computer control systems in military aircraft and other critical applications. A promising solution is to interpose an emulator program between the original "legacy" software and a replacement processor. Unfortunately, no techniques exist for accurately verifying that this procedure preserves the original system's functional and timing behaviour. A particular challenge is that processor emulations involve both legacy code and new subroutines, written in different programming languages. This project will enable verification of safety and mission-critical emulated systems by devising a multilingual modelling and reasoning formalism, based on program refinement theory.Read moreRead less
The Management To Optimise Diabetes And MEtabolic Syndrome Risk Reduction Via Nurse-led Intervention (MODERN) Study
Funder
National Health and Medical Research Council
Funding Amount
$1,445,861.00
Summary
There is increasing recognition of society’s responsibility to provide effective and sustainable health care to the entire population and not just selected parts. This practical study will test the impact of a nurse-led, multidisciplinary prevention program to reduce the risk of future cardiovascular events in middle-aged individuals at a high risk of developing cardiovascular disease (CVD) living in regional Australia.
Targeted Development Of AMPK Β2-isoform Allosteric Activators
Funder
National Health and Medical Research Council
Funding Amount
$898,147.00
Summary
Sedentary lifestyles and consumption of high energy foods has led to dramatic increases in the incidence of diseases associated with metabolic dysregulation e.g. type 2 diabetes. An attractive drug target to treat these diseases is AMP-activated protein kinase (AMPK) which functions as a cellular fuel gauge. We have discovered a new drug that crucially activates the form of AMPK found in metabolically active organs. We aim to develop this drug to unlock new therapeutic opportunity.
An extensible framework for analysis of Java language-based security conformance. Java is a programming language and platform running on 3 billion devices. While Java provides a sandbox-based security architecture within the Java Class Library to protect systems from untrusted code downloaded from Internet, it cannot defend against implementation bugs that occur in the Java Class Library. The goal of this project is to provide a formal model of the Java security architecture, which can be used b ....An extensible framework for analysis of Java language-based security conformance. Java is a programming language and platform running on 3 billion devices. While Java provides a sandbox-based security architecture within the Java Class Library to protect systems from untrusted code downloaded from Internet, it cannot defend against implementation bugs that occur in the Java Class Library. The goal of this project is to provide a formal model of the Java security architecture, which can be used by program analysers to identify faulty or insufficient security checks in the Java Class Library that may lead to the sandbox being bypassed.Read moreRead less
Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised impor ....Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised importance, this program will have direct implications in areas of condensed matter physics, quantum statistical mechanics, particle physics, complex systems, quantum information science and technology, quantum computation, engineered quantum systems and nanotechnology. Read moreRead less
Advanced computer simulations of star cluster evolution. The topic of this fellowship is dynamical simulations of star clusters using high-end graphics cards originally developed for the computer gaming industry. The proposed fellowship will thereby enhance Australia's capacity in the exploitation of high-performance computing and will give it a strong position in the new field of graphics card based simulations. The computer cluster built during the fellowship will also be an outstanding enviro ....Advanced computer simulations of star cluster evolution. The topic of this fellowship is dynamical simulations of star clusters using high-end graphics cards originally developed for the computer gaming industry. The proposed fellowship will thereby enhance Australia's capacity in the exploitation of high-performance computing and will give it a strong position in the new field of graphics card based simulations. The computer cluster built during the fellowship will also be an outstanding environment for the training of students. In addition, while Australia has a strong tradition in star cluster astronomy, it has so far not captured a leadership role in the theoretical analysis. The four years of this fellowship will allow it to establish a world-leading position in star cluster simulations.Read moreRead less