Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Improving Indigenous health and wellbeing over the family life course. Improving Indigenous health and wellbeing over the family life course. This project aims to reduce Indigenous health inequalities, a major social and economic problem, by improving the policy relevant evidence base on the determinants of Indigenous health and wellbeing. This project will compare the impact of the family life course on the health and wellbeing of Indigenous and non-Indigenous mothers and children. It will use ....Improving Indigenous health and wellbeing over the family life course. Improving Indigenous health and wellbeing over the family life course. This project aims to reduce Indigenous health inequalities, a major social and economic problem, by improving the policy relevant evidence base on the determinants of Indigenous health and wellbeing. This project will compare the impact of the family life course on the health and wellbeing of Indigenous and non-Indigenous mothers and children. It will use survey data that follows them over time to: 1) identify family structures that enhance or harm health and wellbeing, and; 2) track changes in health and wellbeing before, during and after family transitions (i.e. births, relationship changes). Anticipated results are better targeted policy interventions to reduce Indigenous health inequalities.Read moreRead less
Genetic architecture of species divergence and hybridisation in eucalypts. Eucalypts are an icon of Australia and are of great economic and ecological significance to the nation. They are the most widely planted hardwood trees in the world, but Australia is the centre of origin of most species and the custodian of this important native bioresource. Understanding the evolutionary processes that shape diversity in this internationally significant genus is important for its long-term management a ....Genetic architecture of species divergence and hybridisation in eucalypts. Eucalypts are an icon of Australia and are of great economic and ecological significance to the nation. They are the most widely planted hardwood trees in the world, but Australia is the centre of origin of most species and the custodian of this important native bioresource. Understanding the evolutionary processes that shape diversity in this internationally significant genus is important for its long-term management and conservation. This project links to large international initiatives currently underway for high-density mapping and sequencing of the eucalypt genome, to enhance the flow of information gained back to Australia for scientific, economic and environmental benefit.Read moreRead less
The role of turgor in hyphal extension of the Ascomycete Neurospora crassa. Cellular expansion is an absolute necessity during the growth and development of plants and fungi. This process relies heavily upon the accumulation of inorganic ions. Osmotically driven water influx then creates the hydrostatic pressure that underlies the increase in cell volume. Cellular expansion is normally asymmetric and localised in one small region, such as hyphal tip. How does the cell maintain the turgor that dr ....The role of turgor in hyphal extension of the Ascomycete Neurospora crassa. Cellular expansion is an absolute necessity during the growth and development of plants and fungi. This process relies heavily upon the accumulation of inorganic ions. Osmotically driven water influx then creates the hydrostatic pressure that underlies the increase in cell volume. Cellular expansion is normally asymmetric and localised in one small region, such as hyphal tip. How does the cell maintain the turgor that drives expansion? How is expansion controlled spatially? These questions will be addressed in this project by comprehensive study of ion transport processes in a model organism, Neurospora crassa, using osmotic sensitive and transport mutants.Read moreRead less
Remotely sensed forest water use in space and time. Remotely sensed forest water use in space and time. This project aims to develop and apply new methods to scale forest water use from plot to catchment-level, using relationships between plot-level annual evapotranspiration and biophysical and biochemical properties of stands detectable by unmanned aircraft systems and other remote sensing platforms. Australia's water security depends on understanding how changes in forests from disturbance and ....Remotely sensed forest water use in space and time. Remotely sensed forest water use in space and time. This project aims to develop and apply new methods to scale forest water use from plot to catchment-level, using relationships between plot-level annual evapotranspiration and biophysical and biochemical properties of stands detectable by unmanned aircraft systems and other remote sensing platforms. Australia's water security depends on understanding how changes in forests from disturbance and climate change influence catchment water yields. This project will estimate water yields over time and space in ungauged catchments with disturbed eucalypt forests. This research is expected to enable more effective risk mitigation and planning for augmentations; improved fire management strategies; and better water management of the Murray Darling Basin.Read moreRead less
Rapid method development in pharmaceutical analysis using quality-by-design principles. Chemical analysis using separation methods underpins all stages of drug design and analysis. This project will generate new approaches to greatly reduce the time taken to develop a new method of analysis. This will be achieved through development of new computerised techniques for rapid screening, selection and optimisation of analytical methods.
Industrial Transformation Research Hubs - Grant ID: IH170100009
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Research Hub for Energy-efficient Separation. The ARC Research Hub for Energy-efficient Separation aims to develop advanced separation materials, innovative products and smart processes to reduce the energy consumption of separation processes. The Research Hub will create a multi-disciplinary training platform, supplying a highly-trained workforce for the advanced manufacturing sector, particularly in separation technology–a growth area in which Australia can lead the world. The advancement ....ARC Research Hub for Energy-efficient Separation. The ARC Research Hub for Energy-efficient Separation aims to develop advanced separation materials, innovative products and smart processes to reduce the energy consumption of separation processes. The Research Hub will create a multi-disciplinary training platform, supplying a highly-trained workforce for the advanced manufacturing sector, particularly in separation technology–a growth area in which Australia can lead the world. The advancement of Australia’s capability as a world-leading technology provider in manufacturing advanced separation materials and equipment will enable Australian industry to become more energy-efficient and cost-competitive in a global economy.Read moreRead less
Function and evolution of insect odorant receptors. This project aims to shed light on how insect odorant receptors function by using comparative genomic studies between the genetic model insect Drosophila melanogaster and a pest species, the Australian sheep blowfly. This project expects to generate knowledge of how specific chemicals activate specific receptors in order to excite sensory neurons and drive behaviour, which is not well understood. Expected outcomes include increased understandin ....Function and evolution of insect odorant receptors. This project aims to shed light on how insect odorant receptors function by using comparative genomic studies between the genetic model insect Drosophila melanogaster and a pest species, the Australian sheep blowfly. This project expects to generate knowledge of how specific chemicals activate specific receptors in order to excite sensory neurons and drive behaviour, which is not well understood. Expected outcomes include increased understanding of olfaction in insects, increased national and international collaboration, and outstanding graduate student training. This research will be of significant future benefit in deriving methods to modify the behaviour of insects of agricultural or medical importance, for example the sheep blowfly. Read moreRead less
Unravelling the relationship between growth and wood properties in temperate eucalypts. The most important biological traits affecting profit in eucalypt plantations grown for pulpwood are growth, wood density and pulp yield. Shrinkage and collapse are important for timber production. Little information is available on the size and direction of the correlations between these traits, yet they are important in determining selection response in breeding as well as environmental impacts on pulp and ....Unravelling the relationship between growth and wood properties in temperate eucalypts. The most important biological traits affecting profit in eucalypt plantations grown for pulpwood are growth, wood density and pulp yield. Shrinkage and collapse are important for timber production. Little information is available on the size and direction of the correlations between these traits, yet they are important in determining selection response in breeding as well as environmental impacts on pulp and sawlog yield. The collaborating growers and breeders have brought together a unique base of Eucalyptus globulus and E. nitens field trials that will allow an integrated quantitative and molecular genetic study of the interrelationships amongst these key profit traits.Read moreRead less
Contribution of hybridisation to genetic diversity and adaptation in Eucalyptus. The eucalypt gene pool is an outstandingly important bioresource for Australia. Its effective future management will be based on understanding the extent, causes and significance of genetic variation in eucalypt species. This project investigates a currently overlooked, but potentially important, source of genetic diversity and adaptation in Eucalyptus. The knowledge gained will contribute substantially to our un ....Contribution of hybridisation to genetic diversity and adaptation in Eucalyptus. The eucalypt gene pool is an outstandingly important bioresource for Australia. Its effective future management will be based on understanding the extent, causes and significance of genetic variation in eucalypt species. This project investigates a currently overlooked, but potentially important, source of genetic diversity and adaptation in Eucalyptus. The knowledge gained will contribute substantially to our understanding of eucalypt biology, and will inform decision-making for conservation, revegetation, and sustainable use of seed resources. Through addressing fundamental questions, the project will also provide a uniquely Australian contribution to world research in forest molecular genetics.Read moreRead less