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Australian Laureate Fellowships - Grant ID: FL210100107
Funder
Australian Research Council
Funding Amount
$2,960,000.00
Summary
Tracking nanoparticles: from cell culture to in vivo delivery. Understanding how cells function in the ‘real-time’ context of a living organism is a key challenge in the new era of cell biology. Using super-resolution light microscopy and state-of-the-art correlative electron microscopy together with model systems, this Fellowship aims to deliver new understandings of cells in their natural environment. Significantly, the project will elucidate how proteins or nanoparticles pass from the bloodst ....Tracking nanoparticles: from cell culture to in vivo delivery. Understanding how cells function in the ‘real-time’ context of a living organism is a key challenge in the new era of cell biology. Using super-resolution light microscopy and state-of-the-art correlative electron microscopy together with model systems, this Fellowship aims to deliver new understandings of cells in their natural environment. Significantly, the project will elucidate how proteins or nanoparticles pass from the bloodstream into tissues and then into cells, and in doing so deliver much-needed knowledge of protein and particle trafficking in situ. Outcomes and benefits include leading-edge fundamental science into the function of cells, education, outreach and building of Australian capacity in high-demand skill sets.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL0992270
Funder
Australian Research Council
Funding Amount
$3,080,000.00
Summary
Nutritional Dynamics: from Genes to Individuals to Ecosystems. Understanding how ecosystems function from the perspective of nutritional interactions between individual organisms will contribute to an environmentally sustainable Australia, with particular benefits to rural communities in arid/semi-arid regions. Research on human and animal nutrition, obesity and ageing will provide essential knowledge for promoting and maintaining good health and designing novel treatments for metabolic disorder ....Nutritional Dynamics: from Genes to Individuals to Ecosystems. Understanding how ecosystems function from the perspective of nutritional interactions between individual organisms will contribute to an environmentally sustainable Australia, with particular benefits to rural communities in arid/semi-arid regions. Research on human and animal nutrition, obesity and ageing will provide essential knowledge for promoting and maintaining good health and designing novel treatments for metabolic disorders. New ways of controlling locusts and other pest insects will arise and contribute to safeguarding Australia. New diet optimisation technologies will help transform Australian food production industries. The project will foster creative, innovative science that spans molecular biology to ecosystem dynamics.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL200100057
Funder
Australian Research Council
Funding Amount
$3,311,491.00
Summary
Dynamic Proteins for Nutritious Future Crops. This project aims to understand the processes and genes that regulate synthesis and degradation of proteins in wheat and barley plants. This project will develop methodologies and a new field of research for optimising protein stability in crops. Its significance lies in defining new ways to control protein abundance to increase crop performance and quality and increase the value of recombinant proteins for biotech industries. Expected outcomes will ....Dynamic Proteins for Nutritious Future Crops. This project aims to understand the processes and genes that regulate synthesis and degradation of proteins in wheat and barley plants. This project will develop methodologies and a new field of research for optimising protein stability in crops. Its significance lies in defining new ways to control protein abundance to increase crop performance and quality and increase the value of recombinant proteins for biotech industries. Expected outcomes will enable the protein abundance in plant cells to be designed and control selective protein degradation in plants for the first time. Benefits will include building biotechnology capacity in WA, brokering new collaborations and providing an ideal training environment for students and postdocs.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL180100019
Funder
Australian Research Council
Funding Amount
$2,906,976.00
Summary
An in situ structural study of Drosophila embryonic patterning. This project aims to develop and deploy an in situ structural biology approach, which enables direct visualisation of large macromolecular structures in cells, to be used in combination with molecular genetics, proteomics and computational biology. In situ structural biology has the potential to revolutionise discovery across life science, providing direct insight into macromolecular structure and function. This project will establi ....An in situ structural study of Drosophila embryonic patterning. This project aims to develop and deploy an in situ structural biology approach, which enables direct visualisation of large macromolecular structures in cells, to be used in combination with molecular genetics, proteomics and computational biology. In situ structural biology has the potential to revolutionise discovery across life science, providing direct insight into macromolecular structure and function. This project will establish the field of in situ structural biology in Australia by studying how a model organism, the fruit fly Drosophila melanogaster controls the development of how the head and tail of the embryo are specified. The project will further develop new instrumentation and approaches that will bring in situ biology to the wider scientific community.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL180100029
Funder
Australian Research Council
Funding Amount
$2,545,000.00
Summary
Nanoionics: Engineering ion transport with two-dimensional materials. This project aims to use graphene and other emerging two-dimensional materials to investigate and manipulate ion transport in nanoscale channels. Nanoionics focuses on understanding ions for transport and storage in nanoscale systems, central to numerous technologies related to water, energy and biomedicine. The project will provide sophisticated methods for revolutionary technological innovations to solve problems in several ....Nanoionics: Engineering ion transport with two-dimensional materials. This project aims to use graphene and other emerging two-dimensional materials to investigate and manipulate ion transport in nanoscale channels. Nanoionics focuses on understanding ions for transport and storage in nanoscale systems, central to numerous technologies related to water, energy and biomedicine. The project will provide sophisticated methods for revolutionary technological innovations to solve problems in several industries including manufacturing, mining, water management and bioengineering. Providing access to previously unavailable structures and materials, the project will support Australia’s manufacturing sector by transforming established industries with next generation technologies. The project will also build capacity of nanoionics engineers and provide intellectual property for commercialised products.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL160100049
Funder
Australian Research Council
Funding Amount
$2,915,738.00
Summary
A molecular investigation into immune function. A molecular investigation into immune function. The project aims to understand how key immune recognition events enable immunity. This project would use a multidisciplinary approach empowered by technological innovations, including the latest advances in atomic and molecular imaging. This research is expected to identify new approaches for the biotechnology industry.
Australian Laureate Fellowships - Grant ID: FL180100139
Funder
Australian Research Council
Funding Amount
$2,973,547.00
Summary
Processes of plant growth that impact agriculture and horticulture. The project aims to discover the genes and processes that control plant shoot architecture, which is a major driver of yield in field, horticultural and forestry crops. Shoot branching is the result of the complex interplay of genes, environment and crop management. By investigating cellular processes governing growth and development, as well as physiology and molecular genetics, this project will enhance Australian capacity and ....Processes of plant growth that impact agriculture and horticulture. The project aims to discover the genes and processes that control plant shoot architecture, which is a major driver of yield in field, horticultural and forestry crops. Shoot branching is the result of the complex interplay of genes, environment and crop management. By investigating cellular processes governing growth and development, as well as physiology and molecular genetics, this project will enhance Australian capacity and multidisciplinary innovation. An improved understanding of shoot branching and how it may be manipulated will improve our knowledge of plant sciences that could contribute to agricultural expansion and food security in Australia and internationally.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL190100056
Funder
Australian Research Council
Funding Amount
$2,795,000.00
Summary
Smart Plants and Solutions for Enhancing Crop Resilience and Yield. The Fellowship aims to produce transformative solutions targeting crop resilience and food security. The chloroplast, the site of photosynthesis, regulates a suite of cellular processes that control photosynthesis, growth and drought resilience. It is expected that a first ever blueprint of the suite of communication networks used by the chloroplast will be discovered. I will use synthetic biology to rewire the network in order ....Smart Plants and Solutions for Enhancing Crop Resilience and Yield. The Fellowship aims to produce transformative solutions targeting crop resilience and food security. The chloroplast, the site of photosynthesis, regulates a suite of cellular processes that control photosynthesis, growth and drought resilience. It is expected that a first ever blueprint of the suite of communication networks used by the chloroplast will be discovered. I will use synthetic biology to rewire the network in order to generate 'smart plants' that are higher-yielding and more resilient in both good and bad seasons by precisely switching on and off resilience. Such re-imaginings of crop systems, inclusive of societal implications, will help chart the future of Australian agriculture.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL110100013
Funder
Australian Research Council
Funding Amount
$2,260,000.00
Summary
New materials for a sustainable energy future. This project will research and develop new selective transport materials to create new sustainable technologies for energy storage (e.g. batteries and capacitors) which will allow greater use of renewable energy sources, desalination and CO2 capture.