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Harnessing Imaging And IT Strategies To Expedite Targeted Treatment And Improve Outcomes In Cerebrovascular Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,914,215.00
Summary
This project will expand on my 25+ years of research in combining neuroimaging methods such as CT and MRI with nascent software tools to better target and coordinate treatment and achieve improved outcomes in cerebrovascular diseases such as stroke. We will develop & improve new CT and MRI methods and leverage latest advances in computer science, such as deep learning and mobile phone app technology, to achieve faster and more accurate identification of patients who can benefit from treatment.
A Network Approach To Mapping And Modifying Brain Changes In Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$2,163,245.00
Summary
Psychosis fundamentally alters a person’s relationship with reality. Brain scans can map which parts of the brain are affected by psychosis, but they cannot reveal the actual disease processes that cause these changes. I will address this gap by integrating brain imaging with genetics and mathematical modelling to identify the brain circuits and molecules that impact risk for psychosis, and to develop targeted therapies that modify risk-related brain dysfunction.
An efficient optical interconnect for superconducting quantum computers. This project aims to develop the technology to connect superconducting quantum computers to the future quantum internet: an optical interconnect. Superconducting qubits are a leading quantum computing system, but their practical use is limited by their microwave operation frequency, as global quantum networks will operate at optical frequencies. This project aims to solve this problem by converting the microwave photons tha ....An efficient optical interconnect for superconducting quantum computers. This project aims to develop the technology to connect superconducting quantum computers to the future quantum internet: an optical interconnect. Superconducting qubits are a leading quantum computing system, but their practical use is limited by their microwave operation frequency, as global quantum networks will operate at optical frequencies. This project aims to solve this problem by converting the microwave photons that carry superconducting quantum information to optical photons. To achieve high efficiency the project will investigate magnetically ordered rare-earth crystals, which uniquely possess the strong optical and microwave coupling required, to build a converter that could greatly enhance the capabilities of quantum computers.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100073
Funder
Australian Research Council
Funding Amount
$1,150,000.00
Summary
A femtosecond beamline for time-resolved momentum microscopy. This project aims to obtain a femtosecond high-harmonic generation beamline that will be integrated with a photoemission electron microscope to create Australia’s first time-resolved momentum microscope. This project expects to use ultrafast spectromicroscopy to observe the changes to the excited electron motion within materials after they absorb light. Expected outcomes of this project include improving our understanding of light-dri ....A femtosecond beamline for time-resolved momentum microscopy. This project aims to obtain a femtosecond high-harmonic generation beamline that will be integrated with a photoemission electron microscope to create Australia’s first time-resolved momentum microscope. This project expects to use ultrafast spectromicroscopy to observe the changes to the excited electron motion within materials after they absorb light. Expected outcomes of this project include improving our understanding of light-driven physical and chemical processes that occur in materials and optoelectronic devices. This should provide significant benefits through the development of new cost effective and efficient materials for energy harvesting, sensors and photocatalysts.Read moreRead less
Emergent Behaviours in Spin Crossover Materials. This project aims to develop new molecular materials in which the incorporation of electronic switching leads to the emergence of fundamentally new chemical and physical phenomena. Through an innovative interdisciplinary approach that targets interesting new forms of interplay at the nanoscale this project expects to generate step-change advances in the understanding of spin-switching materials. Significant anticipated outcomes and benefits includ ....Emergent Behaviours in Spin Crossover Materials. This project aims to develop new molecular materials in which the incorporation of electronic switching leads to the emergence of fundamentally new chemical and physical phenomena. Through an innovative interdisciplinary approach that targets interesting new forms of interplay at the nanoscale this project expects to generate step-change advances in the understanding of spin-switching materials. Significant anticipated outcomes and benefits include identification and development of several new classes of materials function, each of major fundamental interest, and to the generation of advanced new materials worthy of commercial development in electronic device, actuator, sensor and gas separations technologies.Read moreRead less
Multidimensional Coherent Spectroscopy of Strongly Correlated Materials. By applying new types of spectroscopy, this project aims to address the gaps in our understanding of how remarkable macroscopic properties, such as superconductivity, emerge from the fundamental interactions in strongly correlated electron materials. This project will combine theory and experiment to develop a pathway by which multidimensional coherent spectroscopy can disentangle the competing interactions that make these ....Multidimensional Coherent Spectroscopy of Strongly Correlated Materials. By applying new types of spectroscopy, this project aims to address the gaps in our understanding of how remarkable macroscopic properties, such as superconductivity, emerge from the fundamental interactions in strongly correlated electron materials. This project will combine theory and experiment to develop a pathway by which multidimensional coherent spectroscopy can disentangle the competing interactions that make these materials so complex, but also potentially useful. By delivering an understanding of the interplay between different microscopic processes, the project will make it more feasible to control them. This will allow for the design new controllable quantum materials that can be the basis for future technologies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100124
Funder
Australian Research Council
Funding Amount
$538,590.00
Summary
An Advanced Ultrafast Laser Spectroscopy Facility in Queensland. The project aims to establish a world-class ultrafast laser spectroscopy facility to investigate how molecules interact with visible or ultraviolet light. Light-matter interactions are key to energy generation in nature through photosynthesis as well as everyday technologies including optical communications and displays. This project expects to generate new knowledge in on how light interacts with matter at the molecular level. Exp ....An Advanced Ultrafast Laser Spectroscopy Facility in Queensland. The project aims to establish a world-class ultrafast laser spectroscopy facility to investigate how molecules interact with visible or ultraviolet light. Light-matter interactions are key to energy generation in nature through photosynthesis as well as everyday technologies including optical communications and displays. This project expects to generate new knowledge in on how light interacts with matter at the molecular level. Expected outcomes of the ultrafast spectroscopic measurements will be understanding the fate of light absorbed by or generated in different materials. Application of the knowledge gained will enable the design of materials for more efficient technologies such as solar cells, lighting, and sensors.Read moreRead less
Electronic-vibrational spectroscopy: A new probe for structure and function. This project aims to solve a major challenge in ultrafast spectroscopy: to identify and quantify competing reaction pathways in complex photochemical systems. Ultrafast Spectroscopy provides information on excited-state processes of photochemical reactions, however, unravelling heterogeneous systems with competing parallel processes remains difficult. Multidimensional electronic-vibrational spectroscopy, sensitive to el ....Electronic-vibrational spectroscopy: A new probe for structure and function. This project aims to solve a major challenge in ultrafast spectroscopy: to identify and quantify competing reaction pathways in complex photochemical systems. Ultrafast Spectroscopy provides information on excited-state processes of photochemical reactions, however, unravelling heterogeneous systems with competing parallel processes remains difficult. Multidimensional electronic-vibrational spectroscopy, sensitive to electronic dynamics and molecular structure, is expected to overcome this barrier. This new level of detail will profoundly enhance our understanding of energy and chemical conversion in complex systems and will reveal design targets for optimising next-generation light-energy harvesting, conducting, and emitting materials.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101041
Funder
Australian Research Council
Funding Amount
$423,573.00
Summary
On-Chip Terahertz Nanophotonics for Single Molecule Spectroscopy. This project aims to address fundamental limitations of in-vivo terahertz spectroscopy by developing modular, low-cost, efficient chip-based devices that concentrate and generate intense terahertz fields in nanometer volumes. This project expects to develop new knowledge in the areas of terahertz physics, nonlinear optics and biospectroscopy using several innovative terahertz nano-focusing techniques. Expected outcomes of this pro ....On-Chip Terahertz Nanophotonics for Single Molecule Spectroscopy. This project aims to address fundamental limitations of in-vivo terahertz spectroscopy by developing modular, low-cost, efficient chip-based devices that concentrate and generate intense terahertz fields in nanometer volumes. This project expects to develop new knowledge in the areas of terahertz physics, nonlinear optics and biospectroscopy using several innovative terahertz nano-focusing techniques. Expected outcomes of this project include providing improved techniques to interface terahertz fields to photonic nanostructures and performing in-vivo terahertz spectroscopy of single molecules. This should provide significant benefits in biochemistry and drug research, as well as telecommunications.Read moreRead less
All-solid-state: new hybrid materials for next-generation lithium batteries. The aim of the project is an economically viable design for “all-solid-state” rechargeable batteries. Eliminating organic liquid electrolytes from lithium-ion batteries will dramatically increase safety, range of operating conditions, lifetimes, and energy density. The key technical challenge is keeping solid-solid interfaces intact over thousands of charge/discharge cycles. We will address this by inserting inorganic i ....All-solid-state: new hybrid materials for next-generation lithium batteries. The aim of the project is an economically viable design for “all-solid-state” rechargeable batteries. Eliminating organic liquid electrolytes from lithium-ion batteries will dramatically increase safety, range of operating conditions, lifetimes, and energy density. The key technical challenge is keeping solid-solid interfaces intact over thousands of charge/discharge cycles. We will address this by inserting inorganic interfacial layers that change smoothly from hard ceramic to flexible glass and back again, through rigorous chemical design and synthetic control. This will reduce the stress that causes mechanical failure, while increasing chemical stability so that the latest generation of high-power electrodes can be brought into service.Read moreRead less