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Early Antipsychotic Exposure During Childhood And Adolescence: Does It Lead To Long Term Brain And Behaviour Changes In Adulthood?
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Mental health problems affect at least 9% of Australia's 4.1 million children. With the trend towards prescribing antipsychotic medication “off-label” to control these mental disorders in young people and the long-term consequences of doing so unknown, this timely research program aims to address a critical health issue by providing clinicians with valuable information so they can better balance the risk/benefit ratio before prescribing antipsychotics to young people.
The notion that happiness is an important component of mental health is gaining popularity. Researchers have reported that happiness benefits physical health, however there is currently limited research. In addition, there is limited research assessing the affect of physical health on happiness. Using epidemiological methods, I will investigate the relationship between happiness and health in a database that has measurements collected at three time points in the same 15,000 people over 15 years.
Stroke In Australia: Understanding Variation In Clinical Care And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Stroke is the major cause of death and disability. My ECF research project is designed to identify (1) factors that influence hospital readmissions (2) gaps in hospital care for specific groups who experience stroke using the largest national dataset (40+ hospitals, 17,000+ patients). These data will provide evidence for me to develop and test novel future interventions to reduce inequalities in health care access in order to reduce deaths and disability through improvements in stroke care.
Patient-reported Outcomes And Treatment Preferences In 1,900 Men With Prostate Cancer Participating In Two International, Randomised Clinical Trials
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Men with high-risk or metastatic prostate cancer are faced with difficult and uncertain trade-offs between quantity and quality of life when making a treatment decision. The proposed study extends two promising, ongoing clinical trials by describing the quality of life outcomes and treatment.
An abnormal blood pressure (BP) response to a clinical exercise stress test is a signal for increased cardiovascular disease risk. However, current clinical guidelines do not provide evidence based information surrounding values that may constitute this increased risk. The EXERcise stress Test collaboratION (EXERTION) aims to fill this knowledge gap via establishment of a large, national database of exercise stress test results, linked to acute and chronic cardiovascular disease outcomes.
The Femoroacetabular Impingement Rehabilitation STudy (FIRST): A Participant And Assessor-blinded Randomised Controlled Trial Of Physiotherapy For Hip Impingement.
Funder
National Health and Medical Research Council
Funding Amount
$255,014.00
Summary
Hip impingement is a common cause of hip and groin pain in adults. It is a risk factor for the development of hip arthritis and hip replacement surgery in later life. People with hip impingement have more pain and poorer quality of life (QoL) compared to population norms. This study will determine if physiotherapy can improve pain/QoL in people with hip impingement.
Informing Vaccination Strategies For Pregnant Women Through Linked Population Health Data
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Vaccination during pregnancy has health benefits for mothers and their infants; however, it is a relatively new area of research, and the immediate and long-term consequences for children are currently not well understood. As part of this fellowship, I plan to conduct research into the long-term health impacts of vaccination during pregnancy. This fellowship will build my career as a perinatal epidemiologist and establish expertise in Australia related to vaccines given during pregnancy.
Redressing Aboriginal Heart Health Disparity In Western Australia: Valuing Measurement To Inform Action
Funder
National Health and Medical Research Council
Funding Amount
$307,946.00
Summary
This project aims to make comparisons between Aboriginal and non-Aboriginal people in WA with respect to 1) the occurrence, clinical manifestations and outcomes of selected heart diseases (coronary heart disease, heart failure and dysrhythmias) and major associated co-morbidities and 2) access to acute and continuing medical care for these heart conditions.