Hyper-sensitivity Of The Circadian System To Light In Delayed Sleep Phase Disorder
Funder
National Health and Medical Research Council
Funding Amount
$378,858.00
Summary
Delayed Sleep Phase Disorder (DSPD) is a circadian rhythm sleep disorder characterized by a difficulty in initiating sleep at night and difficulty in waking at times required for work or school. It is associated with excessive daytime sleepiness, reduced academic and work performance, increased anxiety and depression and reduced quality of life. This study examines increased sensitivity of the brain's 24-hour biological clock to light as a cause of the abnormal timing of sleep in DSPD.
Accelerated Telomere Length Attrition Rate In Diabetes And Its Cellular Mechanism
Funder
National Health and Medical Research Council
Funding Amount
$38,381.00
Summary
I am a PhD in Medicine-University of Sydney. My research focus is about telomere dynamic, its mechanism and correlation between telomere length and diabetes attributes. I will compare telomere length between different diabetes groups & examine telomere regulation in cell culture/animal model to compliment my clinical data. The hypothesis: accelerated telomere shortening may co-segregate with diabetes complications and by preserving telomere we could potentially prevent adverse effect of diabetes