Side-Hustles: Young People and Employment-Adjacent Entrepreneurship. This project aims to understand new working biographies created by young people that combine employment with entrepreneurial activities. 'Side-hustles' are increasingly common amongst young workers, but while entrepreneurship is promoted globally as a policy solution to youth unemployment there is no comprehensive evidence base about the nature of young workers' entrepreneurial activities or the outcomes they experience. The ev ....Side-Hustles: Young People and Employment-Adjacent Entrepreneurship. This project aims to understand new working biographies created by young people that combine employment with entrepreneurial activities. 'Side-hustles' are increasingly common amongst young workers, but while entrepreneurship is promoted globally as a policy solution to youth unemployment there is no comprehensive evidence base about the nature of young workers' entrepreneurial activities or the outcomes they experience. The evidence created by this project supports efforts to facilitate youth entrepreneurship, address youth unemployment, and enhance Australia's future labour force. Outcomes include policy papers and reports, a policy forum, academic outputs, and a project website, offering benefit to policymakers, educators and employers.Read moreRead less
A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Preventing Early Language Delay In Primary Care Setting:cluster Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$415,133.00
Summary
The trial aims to lower the numbers of children with poor expressive language skills at ages 2 and 3 years, through a sustainable early language promotion program linked to the universal Victorian Maternal and Child Health (M and CH) service, attended by more than 75% of Victorian children at 12 months of age. The trial targets the 20% of toddlers most at risk of expressive language delay, by virtue of having limited or no spoken vocabulary at 18 months of age. It also aims to lower the numbers ....The trial aims to lower the numbers of children with poor expressive language skills at ages 2 and 3 years, through a sustainable early language promotion program linked to the universal Victorian Maternal and Child Health (M and CH) service, attended by more than 75% of Victorian children at 12 months of age. The trial targets the 20% of toddlers most at risk of expressive language delay, by virtue of having limited or no spoken vocabulary at 18 months of age. It also aims to lower the numbers of children with behaviour problems (strongly linked to language delay), to determine the acceptability and cost-effectiveness of the approach, and to determine whether it differentially benefits disadvantaged children.Read moreRead less
Addressing Evidence Gaps And Developing A Novel Treatment To Reduce The Burden Of Post-traumatic Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Arthritis caused by knee injury has a devastating personal and economic impact. Research is needed to develop strategies to prevent arthritis and improve outcomes for people living with arthritis. This research will improve treatment of knee injury to reduce arthritis risk, understand why some people are more likely to get knee arthritis, and develop a new treatment to improve outcomes for people living with knee arthritis. A clinical trial will determine if this treatment achieves this aim.
Music Therapy Interventions For Dementia: Cluster Randomised Control Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,014,430.00
Summary
Music therapy interventions are increasingly used in aged care facilities across Australia, however Australian-based research that tests its effectiveness is scarce. In this study, we track the impact of group music therapy and group singing on levels of depression, cognitive function, quality of life, and other symptoms of dementia. By providing music therapy programs across sites in Victoria, NSW and Queensland, we will also evaluate the cost effectiveness of the intervention.
Benefits Of Home-based Multidisciplinary Rehabilitation In Non Small Cell Lung Cancer
Funder
National Health and Medical Research Council
Funding Amount
$581,039.00
Summary
Lung cancer is the third leading cause of death in Australia. People with lung cancer experience a complex mix of symptoms that can provoke significant distress and impair physical function. This study aims to develop and test a home based exercise and self-management support program to increase function and physical activity levels, reduce levels of depression and improve quality of life of people with lung cancer.
Youth, religion and sexuality: digital media, school cultures, exemptions. This project aims to understand the knowledges and practices about sexuality and religion that form the everyday worlds of young people who are religious. This should provide significant new knowledge about a key time in the development of a young person’s identity via a nationwide, deep yet comparative approach. Expected outcomes include strategic health policy and curriculum development advice that responds to current d ....Youth, religion and sexuality: digital media, school cultures, exemptions. This project aims to understand the knowledges and practices about sexuality and religion that form the everyday worlds of young people who are religious. This should provide significant new knowledge about a key time in the development of a young person’s identity via a nationwide, deep yet comparative approach. Expected outcomes include strategic health policy and curriculum development advice that responds to current debates around religious exemptions to anti-discrimination law and creates better education and health care for religious and LGBTIQ+ youth. Benefits will include increased wellbeing for religious LGBTIQ+ youth, conservatively religious and newly arrived youth communities in Australia.Read moreRead less
Evolutionary signficance of sexual conflict in orb-web spiders. Multiple mating by females creates intense competition between ejaculates over the fertilisation of her eggs, and has a profound influence on male and female life history and mating strategies. In orb-web spiders, sexual cannibalism creates further conflicts of interest because the male may forfeit future matings. This project examines how life-history and mating strategies interact in these spiders, by identifying the mechanisms t ....Evolutionary signficance of sexual conflict in orb-web spiders. Multiple mating by females creates intense competition between ejaculates over the fertilisation of her eggs, and has a profound influence on male and female life history and mating strategies. In orb-web spiders, sexual cannibalism creates further conflicts of interest because the male may forfeit future matings. This project examines how life-history and mating strategies interact in these spiders, by identifying the mechanisms that determine the outcome of sperm competition; the selection pressures favouring sexual size dimorphism and male size variation; the influence of sexual cannibalism on male mating strategies; and the relationship between female feeding history and her mating behaviour.Read moreRead less
Experimental evolution in the mitochondrion. This project aims to discover if the genetic variation in mitochondria (our energy centres) contributes to evolutionary adaptation. This is a long-debated hypothesis in evolutionary biology. This project will take an inter-disciplinary approach, involving experimental evolution, an ecological framework, the measurement of organismal physiologies, and fruit fly genetics. The outcomes could change how biologists view the mitochondria, reveal mitochondri ....Experimental evolution in the mitochondrion. This project aims to discover if the genetic variation in mitochondria (our energy centres) contributes to evolutionary adaptation. This is a long-debated hypothesis in evolutionary biology. This project will take an inter-disciplinary approach, involving experimental evolution, an ecological framework, the measurement of organismal physiologies, and fruit fly genetics. The outcomes could change how biologists view the mitochondria, reveal mitochondria’s role in adaptation to climatic stress, and their contribution to shaping evolutionary trade-offs and conflict between the sexes.Read moreRead less
Mitochondria, maternal inheritance and the evolution of male life-histories. This project aims to unravel the extent to which maternal inheritance of the mitochondrial DNA renders it susceptible to accumulating mutations that are harmful only to males; an evolutionary theory called ‘Mother’s Curse’. Left unchecked, Mother’s Curse could threaten the long-term viability of populations. This project will combine experimental techniques in ecology, fruit fly genetics and a platform for measuring phy ....Mitochondria, maternal inheritance and the evolution of male life-histories. This project aims to unravel the extent to which maternal inheritance of the mitochondrial DNA renders it susceptible to accumulating mutations that are harmful only to males; an evolutionary theory called ‘Mother’s Curse’. Left unchecked, Mother’s Curse could threaten the long-term viability of populations. This project will combine experimental techniques in ecology, fruit fly genetics and a platform for measuring physiological phenotypes to test three hypotheses central to the theory. By testing these hypotheses, the project intends to understand the causes of sex differences in physiology, longevity and reproductive health, and improve awareness of evolutionary concepts that may ultimately affect human health.Read moreRead less