Regulatory Mechanisms Of Antibody Cytotoxicity For Cancer Therapy
Funder
National Health and Medical Research Council
Funding Amount
$566,087.00
Summary
Use of antibodies for cancer therapy, where a protein is made in the laboratory to recognize and act on cancer cells that have a target antigen, has emerged as an important therapeutic area in oncology. The lewis-y (Ley) antigen is found in over 70% of epithelial cancers. We have developed an antibody against Ley (hu3S193) which can target cancer cells. Our research is aimed at developing optimal cancer cell killing by our anti-Ley antibody.