Psychological User Profiling in the Telecommunications Industry. Recording user behaviour allows businesses to learn about their customers. This is particularly important in telecommunications, since the core business involves a large number of users who vary considerably from one another. This project combines psychological insights with modern statistical methods to develop a psychologically plausible user profiling framework, accounting for the idiosyncratic usage patterns of customers, and t ....Psychological User Profiling in the Telecommunications Industry. Recording user behaviour allows businesses to learn about their customers. This is particularly important in telecommunications, since the core business involves a large number of users who vary considerably from one another. This project combines psychological insights with modern statistical methods to develop a psychologically plausible user profiling framework, accounting for the idiosyncratic usage patterns of customers, and the way in which they change over time. The profiles will be tied to marketing prospects through interviews and surveys. Applied benefits include the ability to predict, understand and act upon user behaviour. The project also adds substantially to theories of memory, individual differences and decision-making.Read moreRead less
Before and after the Last Ice Age: GunaiKurnai archaeology along the Snowy. This project aims to transform our understanding of the deep-time Aboriginal occupation of Victoria's Snowy River landscape, by excavating a network of sites dating back to >52,000 years. This project expects to generate new knowledge in archaeology and palaeoclimatology through partnership research in Gunaikurnai Country. Expected outcomes of this project include unprecedented details of Aboriginal occupation, ritual in ....Before and after the Last Ice Age: GunaiKurnai archaeology along the Snowy. This project aims to transform our understanding of the deep-time Aboriginal occupation of Victoria's Snowy River landscape, by excavating a network of sites dating back to >52,000 years. This project expects to generate new knowledge in archaeology and palaeoclimatology through partnership research in Gunaikurnai Country. Expected outcomes of this project include unprecedented details of Aboriginal occupation, ritual installations, wooden artefacts, ancient human DNA, use of deep caves and open landscapes, and economic strategies dating back to the Last Ice Age and beyond. This should provide significant benefits in community research, greater social understandings of Aboriginal connections with Country, and a more inclusive Australia.Read moreRead less
Interactions of Insulin-like Growth Factors and their Binding Proteins with Vitronectin: a structural basis for antagonist design and development. Tissue Therapies Ltd has shown that a patented combination of three biosynthetic molecules, VitroGroR, can promote tissue repair effectively. This project will use biophysical and biochemical techniques to investigate precisely how these molecules interact, and hence provide a rational basis for future developments and improvements of this exciting n ....Interactions of Insulin-like Growth Factors and their Binding Proteins with Vitronectin: a structural basis for antagonist design and development. Tissue Therapies Ltd has shown that a patented combination of three biosynthetic molecules, VitroGroR, can promote tissue repair effectively. This project will use biophysical and biochemical techniques to investigate precisely how these molecules interact, and hence provide a rational basis for future developments and improvements of this exciting new therapeutic strategy.
Conversely, this information would also facilitate the development of antagonists to VitroGroR complexes would provide novel opportunities to treat diseases such as cancer and atherosclerosis that involve excessive production of its component molecules.Read moreRead less
Australian cultural and creative activity: A population and hotspot analysis. This project aims to grasp the contemporary dynamics of cultural and creative activity in Australia. It represents a major innovation, bringing together population-level and comparative studies of local cultural and creative activity. The comprehensive project will advance the integration of quantitative and qualitative research strategies, painting a complete national picture, while also exploring the factors that are ....Australian cultural and creative activity: A population and hotspot analysis. This project aims to grasp the contemporary dynamics of cultural and creative activity in Australia. It represents a major innovation, bringing together population-level and comparative studies of local cultural and creative activity. The comprehensive project will advance the integration of quantitative and qualitative research strategies, painting a complete national picture, while also exploring the factors that are producing local and regional creative hotspots. The project will deliver outputs such as reports and forums that are framed in close collaboration with partners in order to deliver outcomes such as better-targeted policy and program initiatives. This will provide national cultural and policy benefits from placing the creative sector in front of policy makers as a vital contributor to high growth, labour-intensive economic activity in the context of the Australian economy in transition.Read moreRead less
New approaches measuring Australia’s creative workforce: Beyond the Census . This project aims to develop new approaches to measuring Australia’s creative workforce to address increasingly urgent questions about the value of this growing but poorly understood part of the economy and society. It expects to develop and demonstrate novel methods for capturing a range of creative activity currently at the margins of traditional measurement typified by the Census. Expected outcomes, which will benefi ....New approaches measuring Australia’s creative workforce: Beyond the Census . This project aims to develop new approaches to measuring Australia’s creative workforce to address increasingly urgent questions about the value of this growing but poorly understood part of the economy and society. It expects to develop and demonstrate novel methods for capturing a range of creative activity currently at the margins of traditional measurement typified by the Census. Expected outcomes, which will benefit industry partners, the cultural and creative industries, and international scholarship, include new understandings of the scope of creative qualifications, the contribution of creatives working outside the creative industries, the extent of second and other incomes, and the value of volunteering and online entrepreneurship.Read moreRead less
Improving the efficiency of bovine oocyte maturation in vitro. For the dairy and beef industries, the hundreds of eggs (oocytes) in a high value cow's ovary that fail to produce a pregnancy are a wasted genetic resource. A key technology to unlocking this resource is in vitro maturation of oocytes, but the process is inefficient. One possible cause is that the current approaches to maturing oocytes in vitro do not adequately mimic the natural process in vivo. We will design new systems to matu ....Improving the efficiency of bovine oocyte maturation in vitro. For the dairy and beef industries, the hundreds of eggs (oocytes) in a high value cow's ovary that fail to produce a pregnancy are a wasted genetic resource. A key technology to unlocking this resource is in vitro maturation of oocytes, but the process is inefficient. One possible cause is that the current approaches to maturing oocytes in vitro do not adequately mimic the natural process in vivo. We will design new systems to mature cow oocytes in vitro by altering the chemical composition of maturation medium, thus improving the efficiency of laboratory embryo production and related technologies.Read moreRead less
Investigating the archaeological values of Marra cultural heritage sites. This project aims to investigate the archaeological landscape of Limmen National Park, the traditional Country of the Marra people, and to inform the creation of a cultural heritage management plan. It builds on a long-standing relationship with the Marra and the urgency to preserve their cultural knowledge associated with the Park. The project will use a two-way thinking methodology, combining contemporary Aboriginal know ....Investigating the archaeological values of Marra cultural heritage sites. This project aims to investigate the archaeological landscape of Limmen National Park, the traditional Country of the Marra people, and to inform the creation of a cultural heritage management plan. It builds on a long-standing relationship with the Marra and the urgency to preserve their cultural knowledge associated with the Park. The project will use a two-way thinking methodology, combining contemporary Aboriginal knowledge with archaeological and anthropological data to understand the meaning of the archaeological record for Aboriginal people today. Key outcomes include data for continent-wide archaeological narratives, a holistic blueprint to help manage the Park’s cultural heritage, and an archive for Traditional Owner research.Read moreRead less
Bio-MEMS eye sensor for continuous monitoring of intraocular pressure. Glaucoma is a leading cause of preventable blindness, particularly prevalent in the 60+ population, caused by elevated intraocular pressure (IOP). Current treatment to monitor and prevent glaucoma-related blindness is by lowering IOP with eye-drops, laser therapy or surgery. This project directly benefits our aging population by ensuring independence and quality of life, whilst reducing long-term medical and social costs. By ....Bio-MEMS eye sensor for continuous monitoring of intraocular pressure. Glaucoma is a leading cause of preventable blindness, particularly prevalent in the 60+ population, caused by elevated intraocular pressure (IOP). Current treatment to monitor and prevent glaucoma-related blindness is by lowering IOP with eye-drops, laser therapy or surgery. This project directly benefits our aging population by ensuring independence and quality of life, whilst reducing long-term medical and social costs. By incorporating nanotechnology with ophthalmology we will provide an economic solution to long-term, reliable, home-monitoring of IOP. An implantable IOP sensor, will identify patients requiring more invasive treatment compared with those with less aggressive disease, leading to better health resource utilisation.Read moreRead less
The mechanisms and roles of receptor clustering in cell activation and wound healing by growth factors. Growth factors regulate cell proliferation, migration and differentation by interaction with receptors. Such receptors are usually localized at the cell surface, and require intracellular transduction systems to transmit the signal to the cell interior. We have recently shown the hormone-induced clustering of heterologous hormone receptors in cells, and that this occurs with the co-clustering ....The mechanisms and roles of receptor clustering in cell activation and wound healing by growth factors. Growth factors regulate cell proliferation, migration and differentation by interaction with receptors. Such receptors are usually localized at the cell surface, and require intracellular transduction systems to transmit the signal to the cell interior. We have recently shown the hormone-induced clustering of heterologous hormone receptors in cells, and that this occurs with the co-clustering of downstream signalling molecules at sites of engagement with the extracellular matrix. In addition, we have found that cells presented with an extracellular matrix respond better to subsequent growth factor stimulation. The project aims to determine the cellular mechanisms underlying receptor clustering and the basis of the receptor-extracellular matrix interaction. This will enhance our understanding of growth factor function in a number of conditions, including wound healing. We will extend our in vitro results to the animal model to define parameters for enhanced wound repair.Read moreRead less
Effective clinical handover communication: improving patient safety, experiences and outcomes. Communication in clinical handover (transfer of responsibility for patient care) plays a causal role in many adverse events. This project will contribute new knowledge for improvements in handover communication which will be shared across hospitals and health departments nationally to improve patient safety and reduce healthcare costs.