Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100051
Funder
Australian Research Council
Funding Amount
$320,000.00
Summary
An advanced X-ray facility for surface and in-situ materials characterization. An advanced X-ray facility for surface and in-situ materials characterisation: Materials properties are crucial to the performance of devices and structures, and detailed characterisation at a molecular level is important for optimizing new materials. X-rays are a powerful means of achieving the required level of detail in structural characterisation. The aim of this project is to make available an extremely bright X- ....An advanced X-ray facility for surface and in-situ materials characterization. An advanced X-ray facility for surface and in-situ materials characterisation: Materials properties are crucial to the performance of devices and structures, and detailed characterisation at a molecular level is important for optimizing new materials. X-rays are a powerful means of achieving the required level of detail in structural characterisation. The aim of this project is to make available an extremely bright X-ray source with a suite of advanced analytical tools, including surface structural analysis by reflectometry and grazing incidence diffraction and materials structure determination using powder diffraction and microdiffraction at high and low temperatures. The functions of this facility are broad and its applications include materials science, organic electronics, biomaterials and engineering.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101550
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Functional polymer encapsulation to enhance biological performance of implantable materials. This project will develop biomaterial films from essential oils using a low-cost 'green' technology. Applied to commercial biomaterials, these films will minimise infections and inflammations commonly associated with implants. These films will also enable clinical use of metallic resorbable implants for tissue engineering and function restoration.
Discovery Early Career Researcher Award - Grant ID: DE170100607
Funder
Australian Research Council
Funding Amount
$302,624.00
Summary
Catalytically active surface for hydrogen evolution. This project aims to develop classes of active surface on catalysts for efficient electrocatalytic hydrogen production. Targeted catalysts with abundant transitional metal active sites are a new frontier in electrocatalysis. This project intends to develop vapour-phase hydrothermal approaches to effectively in-situ grow single crystal catalysts with rich metal centres and to further boost their activities by in-situ doping with heteroatoms. Ex ....Catalytically active surface for hydrogen evolution. This project aims to develop classes of active surface on catalysts for efficient electrocatalytic hydrogen production. Targeted catalysts with abundant transitional metal active sites are a new frontier in electrocatalysis. This project intends to develop vapour-phase hydrothermal approaches to effectively in-situ grow single crystal catalysts with rich metal centres and to further boost their activities by in-situ doping with heteroatoms. Expected outcomes include robust fabrication means for atomic construction of active surfaces and improved understanding of active sites for hydrogen evolution reaction.Read moreRead less
A Nano-platform for affordable and ultra-sensitive bio-marker detection. This project aims to develop a next-generation nano-platform and lateral flow assays (LFA) device for ultra-sensitive detection of biomarkers. LFA’s are used for the rapid detection of biomarkers; however, their sensitivity is relatively low. The preparation of innovative porous silica nanoparticles with uniform particle size and controllable structures (pore size, pore structure, internal surface functionality and density ....A Nano-platform for affordable and ultra-sensitive bio-marker detection. This project aims to develop a next-generation nano-platform and lateral flow assays (LFA) device for ultra-sensitive detection of biomarkers. LFA’s are used for the rapid detection of biomarkers; however, their sensitivity is relatively low. The preparation of innovative porous silica nanoparticles with uniform particle size and controllable structures (pore size, pore structure, internal surface functionality and density) will enable higher loading of quantum dots and enhanced detection sensitivity. Improving the detection sensitivity of the inexpensive and disposable LFA diagnostic technology will open up new applications for rapid and accurate biomarker detection. The resulting technology will advance Australian industrial capability and competiveness in the global lateral flow assays market, which is estimated to be valued at US$ 6.78 billion by 2020.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100892
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structur ....Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structural design and surface modification. The success of the project will benefit Australia’s booming graphite industry and promote Australian competitiveness in wearable electronics markets.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190101351
Funder
Australian Research Council
Funding Amount
$406,000.00
Summary
Designing new perovskite quantum dots for efficient solar energy conversion. This project aims to rationally design new perovskite quantum dots featuring prominent phase and thermal stability in humid air and remarkable optoelectronic properties. These will be crucial for the development of next-generation flexible, lightweight solar energy conversion devices. This project expects to generate new knowledge in the fundamental mechanism of functional materials for more efficient solar energy conve ....Designing new perovskite quantum dots for efficient solar energy conversion. This project aims to rationally design new perovskite quantum dots featuring prominent phase and thermal stability in humid air and remarkable optoelectronic properties. These will be crucial for the development of next-generation flexible, lightweight solar energy conversion devices. This project expects to generate new knowledge in the fundamental mechanism of functional materials for more efficient solar energy conversion. Expected outcomes include new advanced materials and commercially compelling technology for sustainable and decentralised energy utilisation. This project will position Australia at the frontier of clean energy, flexible optoelectronics and related research areas.Read moreRead less
Fabrication of Novel Core-Shell Nanocomposites as Targeted Carriers. This project intends to design and fabricate a group of core-shell nanocomposites as new-generation carriers for effective drug delivery applications. The unique core-shell functional materials possess radiation/magnetic-responsive release behaviour due to the nanoparticle core, and good biocompatibility, ultra-high loading capacity and outstanding targeting specificity due to the surface-modified mesoporous metal-organic frame ....Fabrication of Novel Core-Shell Nanocomposites as Targeted Carriers. This project intends to design and fabricate a group of core-shell nanocomposites as new-generation carriers for effective drug delivery applications. The unique core-shell functional materials possess radiation/magnetic-responsive release behaviour due to the nanoparticle core, and good biocompatibility, ultra-high loading capacity and outstanding targeting specificity due to the surface-modified mesoporous metal-organic frameworks shell. Development of such hybrid materials would overcome the existing challenges such as low loading capacity, poor release control. The application of such materials may help to improve the efficacy of pharmaceutical therapies.Read moreRead less
Poly(dendrimer) organic light-emitting diodes. This project aims to develop ultrathin efficient emissive technologies based on low embedded energy organic light-emitting diodes (OLEDs). It will develop transformative OLEDs that can be used in displays and lighting, by creating semiconductor materials and diode architectures that optimise each step in light generation, from charge injection, transport and capture to light emission. The efficiency improvements made possible by OLED technology can ....Poly(dendrimer) organic light-emitting diodes. This project aims to develop ultrathin efficient emissive technologies based on low embedded energy organic light-emitting diodes (OLEDs). It will develop transformative OLEDs that can be used in displays and lighting, by creating semiconductor materials and diode architectures that optimise each step in light generation, from charge injection, transport and capture to light emission. The efficiency improvements made possible by OLED technology can reduce electricity consumption, carbon dioxide emissions, and the cost of living.Read moreRead less
Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible ....Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible polymers as a power source and thin film graphene/polymer nanomaterial as an electrode/energy storage media. Second, it aims to design invisible carbon nanotube inks for optical authentication via near infrared activation. Both technologies are expected to thwart sophisticated counterfeits, particularly those supported by organised crime.Read moreRead less