Where do inductive biases come from? A Bayesian investigation. This project aims to investigate the origin of our thinking and learning biases using state-of-the-art mathematical models and sophisticated experimental designs. Expected outcomes include bridging the gap between human and machine learning by pairing mathematical modelling with experimental work, forming a necessary step toward the development of machine systems that can reason like people do. This will provide significant benefits ....Where do inductive biases come from? A Bayesian investigation. This project aims to investigate the origin of our thinking and learning biases using state-of-the-art mathematical models and sophisticated experimental designs. Expected outcomes include bridging the gap between human and machine learning by pairing mathematical modelling with experimental work, forming a necessary step toward the development of machine systems that can reason like people do. This will provide significant benefits such as understanding how people operate so effectively in real environments, when even the most powerful computers struggle to handle the complexities of everyday learning problems.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
Organically-Capped Copper Nanowires for Soft Electronic Skin Sensors. Soft skin-like electronics can enable applications that are impossible to achieve with today's rigid circuit board technologies. However, it is difficult to realise such future soft electronics with traditional materials and conventional manufacturing methodologies. This project aims to synthesise novel organically-capped copper nanowires as electronic inks (e-inks) for developing cost-effective, soft, stretchable conductor (e ....Organically-Capped Copper Nanowires for Soft Electronic Skin Sensors. Soft skin-like electronics can enable applications that are impossible to achieve with today's rigid circuit board technologies. However, it is difficult to realise such future soft electronics with traditional materials and conventional manufacturing methodologies. This project aims to synthesise novel organically-capped copper nanowires as electronic inks (e-inks) for developing cost-effective, soft, stretchable conductor (e-skin) sensors, which are wearable for monitoring blood pulses, body motions and hand gestures in real-time and in situ. This is expected to advance our knowledge in nanotechnology and generate patentable technologies in soft e-skin sensors, and to bring significant scientific and economic gains to Australia.Read moreRead less
ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to unde ....ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to understand how single cells react to and communicate with their surroundings. This science will underpin a new generation of devices capable of probing the response of cells within individuals to environmental conditions or treatment, creating innovative and powerful new sensing platforms.Read moreRead less
Special Research Initiatives - Grant ID: SR120300015
Funder
Australian Research Council
Funding Amount
$16,000,000.00
Summary
The Science of Learning Research Centre. In this innovative new Centre, researchers in education, neuroscience and cognitive psychology will work together with teachers to understand the learning process. This collaboration will establish new criteria to assess the impact of different types of learning and strategies to inform teaching practices of benefit to all Australians.
Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This projec ....Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This project will push the boundaries of a variety of micro and nano "probe-free" microscopies to provide fundamental insights into these life processes, which could ultimately lead to improvements in the diagnosis, prevention and treatment of diseases.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100177
Funder
Australian Research Council
Funding Amount
$440,000.00
Summary
National Live Cell Scanning Platform for Nanoparticle Tracking. National live cell scanning platform for nanoparticle tracking: The aim of the project is to establish a multi-disciplinary, multi-user, self-correlated scanning facility to reach a new level of temporal and spatial precision for real-time tracking and quantification of biomolecules and nanoparticles within large populations of living cells. The facility will consist of a live-cell spinning-disc confocal microscope, a correlated bio ....National Live Cell Scanning Platform for Nanoparticle Tracking. National live cell scanning platform for nanoparticle tracking: The aim of the project is to establish a multi-disciplinary, multi-user, self-correlated scanning facility to reach a new level of temporal and spatial precision for real-time tracking and quantification of biomolecules and nanoparticles within large populations of living cells. The facility will consist of a live-cell spinning-disc confocal microscope, a correlated biological atomic force microscope, and remote access facilities. It is expected that with superior optical characterisation and mechanical manipulation, the automated orthogonal scanning facility will open new avenues to reveal unprecedented information from biological and pathological processes. The collaborative facility will support world-class researchers in the multi-disciplinary areas of physical, material and life sciences, placing Australia at the forefront of nanoscale biophotonics.Read moreRead less
Learning from others: Inductive reasoning based on human-generated data. Most of the data we see every day, from politics to gossip, comes from other people. Making inferences about such data is difficult because the people who provided it may have biases or limitations in their knowledge that we do not know about and must figure out. This project uses a series of experiments tied to normative computational models of social reasoning to explore how people solve this problem. This work has the po ....Learning from others: Inductive reasoning based on human-generated data. Most of the data we see every day, from politics to gossip, comes from other people. Making inferences about such data is difficult because the people who provided it may have biases or limitations in their knowledge that we do not know about and must figure out. This project uses a series of experiments tied to normative computational models of social reasoning to explore how people solve this problem. This work has the potential to make a major impact in understanding how information is understood and shared, especially when it is about topics that people lack firsthand knowledge about, like climate change. The computational models also have applications to the development of expert systems upon which our information economy relies.Read moreRead less
Development of functional dendrimer-like inorganic nanomaterials with hierarchical pores for biological applications. This project aims to engineer a series of brand new dendrimer-like mesoporous silica nanoparticles with hierarchical pore structure and favourable surface functionality as nanocarriers to construct a smart delivery system. Unique materials structure and surface functionalisation design can endow the system with advanced characteristics of the co-loading of different therapeutic a ....Development of functional dendrimer-like inorganic nanomaterials with hierarchical pores for biological applications. This project aims to engineer a series of brand new dendrimer-like mesoporous silica nanoparticles with hierarchical pore structure and favourable surface functionality as nanocarriers to construct a smart delivery system. Unique materials structure and surface functionalisation design can endow the system with advanced characteristics of the co-loading of different therapeutic agents and the highly efficient target delivery that are not readily obtainable using other organic or inorganic materials. The proposed delivery systems are of great importance for improving the therapeutic efficiency of complex diseases, and in general, for expanding human’s life span.Read moreRead less
Molecular insights into bacterial metal ion homeostasis and toxicity. This project aims to measure bacterial cellular metal concentrations, elucidate mechanisms cells use to adapt to changing extracellular metal concentrations, and reveal the molecular targets of metal toxicity. Metal ions are essential to all forms of life, and half of all proteins use metal ions for cellular chemical processes. However, how cells precisely balance sufficient metal ions for essential cellular chemistry without ....Molecular insights into bacterial metal ion homeostasis and toxicity. This project aims to measure bacterial cellular metal concentrations, elucidate mechanisms cells use to adapt to changing extracellular metal concentrations, and reveal the molecular targets of metal toxicity. Metal ions are essential to all forms of life, and half of all proteins use metal ions for cellular chemical processes. However, how cells precisely balance sufficient metal ions for essential cellular chemistry without accumulating a toxic excess (metal homeostasis) is poorly understood. Discovering the roles of metal ions in bacterial cells will be key to defining the chemical biology of living systems and will provide information essential to understanding how microbes adapt to changing environments.Read moreRead less