Inventiveness and the progress of product innovation. Quantitative models of inventiveness will be used to forecast the potential rate of improvement of a technology and to re-design products to improve more rapidly and steadily. By focusing on innovation in products and technologies in energy conversion, this research can guide development funding for low-carbon energy generation.
Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biologic ....Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biological environments. The expected outcome is to generate new material design rules to facilitate wireless neuromodulation technologies in biomedical engineering. The project will position Australia as a leader in bionic devices by creating a new 3D bioprinting hub for low-cost fabrication of bioelectronic systems.Read moreRead less
Dealing with distraction: understanding recovery after interruption. Interruptions impair cognitive performance but modern environments have normalised distractions in our workplaces, homes, schools and cars. Daily tragedies occur because people are unaware of their attentional capacity limits. This Fellowship explores the consequences of interruption in moving displays using cutting-edge methods to determine how the brain holds information over an interruption and the process of attentional rec ....Dealing with distraction: understanding recovery after interruption. Interruptions impair cognitive performance but modern environments have normalised distractions in our workplaces, homes, schools and cars. Daily tragedies occur because people are unaware of their attentional capacity limits. This Fellowship explores the consequences of interruption in moving displays using cutting-edge methods to determine how the brain holds information over an interruption and the process of attentional recovery. It includes translational work determining effective ways to raise awareness of attention limits and guide policy. The outcomes will advance knowledge of the mechanisms of recovery from interruption, raise awareness of capacity limits beyond academia, and guide policy to improve safety.Read moreRead less
Protein Structural-Dynamics at Solid Surfaces: Beyond Static Snapshots. The project will use High-Speed Atomic Force Microscopy to directly visualize single proteins in ‘action’ with surfaces, revealing their dynamics at unprecedented combined structural and temporal resolution in liquid. Such characterization moves beyond static ‘snapshots’ of protein structure, toward the dynamic changes in protein conformation that will enable new exploration of key biological processes at liquid-solid interf ....Protein Structural-Dynamics at Solid Surfaces: Beyond Static Snapshots. The project will use High-Speed Atomic Force Microscopy to directly visualize single proteins in ‘action’ with surfaces, revealing their dynamics at unprecedented combined structural and temporal resolution in liquid. Such characterization moves beyond static ‘snapshots’ of protein structure, toward the dynamic changes in protein conformation that will enable new exploration of key biological processes at liquid-solid interfaces. New fundamental discoveries will have an impact on technologies such as medical device coatings, biomaterials, biosensors, microfluidics devices, protein purification and diagnostics assays that are critically dependent on the biological function of adsorbed or immobilized proteins.Read moreRead less
Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a so ....Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a solid foundation for realising qualified spintronics materials for spintronics devices. The expected outcomes are low power, high speed, spintronics devices, enhancing Australia’s strength in spintronics research.Read moreRead less
How microbes build their environments through evolutionary feedback. The fitness landscape, a key evolutionary concept, relates genes or traits to reproductive fitness. However, this has been challenged by organisms that distort the landscape by changing their environments. This project aims to develop a new mathematical model that restores the landscape concept by extending it to accommodate niche construction. This framework will be applied to microorganisms that alter their environments, for ....How microbes build their environments through evolutionary feedback. The fitness landscape, a key evolutionary concept, relates genes or traits to reproductive fitness. However, this has been challenged by organisms that distort the landscape by changing their environments. This project aims to develop a new mathematical model that restores the landscape concept by extending it to accommodate niche construction. This framework will be applied to microorganisms that alter their environments, for example, by provoking and subverting the host immune system, and by inducing behavioural change in hosts. These processes alter how natural selection operates on microbes and thus lead to important evolutionary feedback. The model will be used to examine antibiotic resistance, pathogen virulence and how microbiomes develop.Read moreRead less
Next-generation luminescence dating techniques for Earth and archaeological science applications. Chronology is a critical component of geological and archaeological studies. To reconstruct the evolutionary histories of Homo sapiens and other hominin species in their environmental context, we must establish reliable age estimates for key archaeological sites and Quaternary deposits. This project aims to develop new-generation sediment dating techniques using the non-fading infrared stimulated lu ....Next-generation luminescence dating techniques for Earth and archaeological science applications. Chronology is a critical component of geological and archaeological studies. To reconstruct the evolutionary histories of Homo sapiens and other hominin species in their environmental context, we must establish reliable age estimates for key archaeological sites and Quaternary deposits. This project aims to develop new-generation sediment dating techniques using the non-fading infrared stimulated luminescence (IRSL) signal from potassium feldspars. These improved methods will be able to be applied to sites in Africa, Europe and Asia that contain important human fossils and artefacts, including the unique type localities of ‘Denisovans’ and ‘Hobbits’, to answer fundamental questions about the timing of key turning points in human evolution and dispersal.Read moreRead less
Electro-triggered solidification of supercooled fusible alloys. Stiffness is typically considered a static property of a material. Traditionally, once the stiffness is specified, it is not expected to change during operation. This project aims to turn a problem (i.e., supercooling) into an opportunity for creating fusible alloy composites with electroprogrammable stiffness that can outperform state-of-the-art materials by offering all desirable properties. Expected outcomes are the rapid, contin ....Electro-triggered solidification of supercooled fusible alloys. Stiffness is typically considered a static property of a material. Traditionally, once the stiffness is specified, it is not expected to change during operation. This project aims to turn a problem (i.e., supercooling) into an opportunity for creating fusible alloy composites with electroprogrammable stiffness that can outperform state-of-the-art materials by offering all desirable properties. Expected outcomes are the rapid, continuous, large, and reversible change in stiffness of the composite through electrical control. This project will provide significant benefits by enabling an increasing number of emerging applications in areas such as robotics, manufacturing, and consumer wearables that require materials with tuneable stiffness.Read moreRead less
Nanoconfined ionic liquids for electrochemical reduction of carbon dioxide. This project aims to develop ionic liquid-based nanoporous composite catalysts for efficient electrochemical reduction of carbon dioxide into value-added chemicals and fuels using electricity generated from renewable sources. Novel nanoporous catalysts will be constructed and impregnated with a secondary phase of task-specific ionic liquids to promote carbon dioxide reduction. An expected outcome of the project is an und ....Nanoconfined ionic liquids for electrochemical reduction of carbon dioxide. This project aims to develop ionic liquid-based nanoporous composite catalysts for efficient electrochemical reduction of carbon dioxide into value-added chemicals and fuels using electricity generated from renewable sources. Novel nanoporous catalysts will be constructed and impregnated with a secondary phase of task-specific ionic liquids to promote carbon dioxide reduction. An expected outcome of the project is an understanding of the fundamental physicochemical and electrochemical behaviour of the nanoconfined ionic liquid/catalyst interfaces which will allow optimisation and enhancement of their properties. This project is expected to contribute to clean energy and sustainable environments.Read moreRead less
Cracking post-translational modification codes in high molecular definition. This project aims to markedly improve the analysis of post-translational modifications (PTM) via intact protein mass spectrometry. Differences in the PTM forms of a protein (modforms) can be crucial in many physiological and metabolic processes. However, current conventional methods cannot accurately separate nor fully assign most protein modforms. A recent discovery has resulted in the ability to separate whole protein ....Cracking post-translational modification codes in high molecular definition. This project aims to markedly improve the analysis of post-translational modifications (PTM) via intact protein mass spectrometry. Differences in the PTM forms of a protein (modforms) can be crucial in many physiological and metabolic processes. However, current conventional methods cannot accurately separate nor fully assign most protein modforms. A recent discovery has resulted in the ability to separate whole protein ions that have the same mass, charge, and collision cross section, but subtly different charge sites. This project aims to leverage this breakthrough by developing novel approaches for separating intact protein modforms and mapping PTM sites. This is expected to be important for future biological discovery.Read moreRead less