Novel Approaches To The Prevention And Treatment Of Chronic Heart Disease And Its Co-morbid Complications
Funder
National Health and Medical Research Council
Funding Amount
$5,793,580.00
Summary
Cardiovascular disease (CVD) and its associated additional disorders constitute major public health problems, especially given the rapidly ageing population which is increasingly affected by obesity and diabetes. This Program will explore novel therapies for the treatment of CVD and associated diseases, particularly focussing on chronic kidney disease, translating preliminary laboratory-based findings into clinical trials and then clinical and epidemiological findings into practice and policy.
Disorders Of Sex Development: Genetics, Diagnosis, Informing Clinical Care
Funder
National Health and Medical Research Council
Funding Amount
$5,751,502.00
Summary
Disorders of sexual development (DSDs) are surprisingly common, and often result in genital abnormalities, gender mis-assignment, infertility and psychological trauma. We will pool our expertise in human genetics, molecular and developmental biology, to find genes important for sex development, identify gene defects that cause DSD, and study their functions. We will liaise with clinicians to apply these findings to the accurate diagnosis and medical care of DSD in children.
From Discovery To Innovation In Stuttering Treatment
Funder
National Health and Medical Research Council
Funding Amount
$5,124,148.00
Summary
Stuttering starts in 2-3-year olds and if not controlled causes a lifetime of social anxiety, and hinders educational and vocational achievement. Recent discoveries by the current team and colleagues have shown the disorder to be far more prevalent, and more of a public health problem, than previously thought. The team has developed efficacious treatments for stuttering children and adults. However, no country can afford the health care needed for all who stutter. The present research is designe ....Stuttering starts in 2-3-year olds and if not controlled causes a lifetime of social anxiety, and hinders educational and vocational achievement. Recent discoveries by the current team and colleagues have shown the disorder to be far more prevalent, and more of a public health problem, than previously thought. The team has developed efficacious treatments for stuttering children and adults. However, no country can afford the health care needed for all who stutter. The present research is designed to solve this problem by developing standalone Internet based stuttering treatments. These will be evaluated in a stepped care treatment approach for people who stutter, in Australia and internationally.Read moreRead less
Tropical Disease - Immunity, Pathogenesis And Vaccine Development: Global Translation
Funder
National Health and Medical Research Council
Funding Amount
$17,988,456.00
Summary
Tropical diseases create a significant human and economic burden worldwide - particularly in resource-poor settings. Around half of the world's population is at risk of malaria. In Australia, Streptococcal and parasitic worm infections are particularly common in indigenous communities. This Program brings together leading experts to tackle these major health challenges. They are investigating how the body reacts to infection and creating new drugs and vaccines to eradicate these diseases.
The development of better ways to prevent and treat influenza infection will be a major step forward in lessening the impact of the virus in communities worldwide. We have assembled a research team of seven groups who will determine the ways in which the effects of influenza can be mitigated through an understanding of the factors which lead to severe disease, and how these can be lessened by novel vaccination and treatment strategies.