Ubiquitin And SUMO DNA Damage Response Signalling At Deprotected Telomeres During The Cell Cycle
Funder
National Health and Medical Research Council
Funding Amount
$302,627.00
Summary
Following genome damage cells stop the cell division process and initiate DNA repair. We discovered that at specific times during cell division his does not happen if the damage signals originate from the chromosome ends (i.e. “telomeres”). We anticipate this is necessary to prevent genomic instability in healthy cells and may be driving genomic instability in cancer cells. Experiments described here will elucidate the molecular mechanisms and biological significance of our observation.
A nation of 'Good Sports'? Cultural citizenship and sport in contemporary Australia. Australia is widely regarded as both characterised and united by sport, but the established sport-nation nexus is undergoing significant change. This project addresses current uses and meanings of sport, media and spectatorship in advancing knowledge and policy relating to sport's dynamic relationship to national identity and cultural citizenship.
Communicating with people who have limited English proficiency. This sociolinguistic project aims to investigate how fluent English speakers interact with people who have limited proficiency. In contemporary Australia such mundane interactions may determine employment, education or health outcomes. While research into language barriers has mostly focused on the experiences of migrants from non-English-speaking backgrounds, this project will investigate how English speakers deal with increasing l ....Communicating with people who have limited English proficiency. This sociolinguistic project aims to investigate how fluent English speakers interact with people who have limited proficiency. In contemporary Australia such mundane interactions may determine employment, education or health outcomes. While research into language barriers has mostly focused on the experiences of migrants from non-English-speaking backgrounds, this project will investigate how English speakers deal with increasing linguistic diversity. Expected outcomes include an understanding of the role of majority members in facilitating the integration of newcomers. This will provide significant socioeconomic benefits for institutions and individuals as they navigate everyday intercultural communication.Read moreRead less
Voice, indexicality and the mediation of diversity on Australian television. Multicultural Australia is a country of many voices, although concern has been expressed about the under-representation of those voices in the media. This project investigates how the voices of minority groups are represented on mainstream Australian television, when they do appear. It examines a substantial body of TV data, from four types of programming: news, sports, advertising and drama. It focuses on minority ethn ....Voice, indexicality and the mediation of diversity on Australian television. Multicultural Australia is a country of many voices, although concern has been expressed about the under-representation of those voices in the media. This project investigates how the voices of minority groups are represented on mainstream Australian television, when they do appear. It examines a substantial body of TV data, from four types of programming: news, sports, advertising and drama. It focuses on minority ethnic voices and on voices linked to different social classes. Close analysis of media processes will be supplemented by consulting professionals and TV viewers. The findings will provide a new perspective on the media’s role in promoting or curtailing cultural literacy and linguistic diversity.Read moreRead less
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