Minimally invasive monitoring of sleep for disease management. Sleep, diet and exercise are the three pillars of wellbeing with poor sleep associated with medical issues such as obesity and congestive heart failure. This project will advance sleep analysis by researching new ways of monitoring that are highly accurate and convenient, enabling physicians to improve the monitoring of significant health issues.
The role of oxytocin in attachment patterns and socio-emotional development. The role of oxytocin in attachment patterns and socio-emotional development. This project aims to better understand how oxytocin mediates links between maternal sensitivity and attachment and child socio-emotional outcomes. The child's emotional health is the most powerful childhood predictor of adult life satisfaction, and evidence points to the pivotal role of the oxytocin system on mother-child interactions and attac ....The role of oxytocin in attachment patterns and socio-emotional development. The role of oxytocin in attachment patterns and socio-emotional development. This project aims to better understand how oxytocin mediates links between maternal sensitivity and attachment and child socio-emotional outcomes. The child's emotional health is the most powerful childhood predictor of adult life satisfaction, and evidence points to the pivotal role of the oxytocin system on mother-child interactions and attachment representations that affect children's socio-emotional development. As a longitudinal study of oxytocin function in mother-child dyads, it examines how genetic, epigenetic and parenting factors determine socio-emotional and temperamental outcomes.Read moreRead less
Metal-air batteries with improved rate capability and safety for hearing applications. Hearing impairment affects on average 20% of the adult population in western society, with the impact being as high as 50% in older adults. Effective hearing devices require a significant amount of power, supplied by a battery, to support their function. Current batteries require very frequent replacement and represent a significant impediment to advances in the technology. This project will develop improved ....Metal-air batteries with improved rate capability and safety for hearing applications. Hearing impairment affects on average 20% of the adult population in western society, with the impact being as high as 50% in older adults. Effective hearing devices require a significant amount of power, supplied by a battery, to support their function. Current batteries require very frequent replacement and represent a significant impediment to advances in the technology. This project will develop improved energy and power density batteries which will lead to immediate implementation of more powerful signal processing algorithms, making hearing aids much more effective and appealing to the user. This, in turn, will improve recipient compliance and thus the quality of life for those with severe hearing impairment. Read moreRead less
Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of el ....Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of electric bacteria into sensor systems, will result in a new platform technology that expands our abilities to protect the ecology, agriculture and health of terrestrial, marine and agricultural at risk areas from economic and environmental damage.Read moreRead less
Deeper and broader life cycle risk assessment - extending the frontier for hybrid methodologies. This project is about combining detailed and global perspectives of environmental health risk from different fields of planning practice. It aims to improve the depth and breadth of the types of information used by government regulators and the community in decisions about the development of capital works.
Taste and Place: the transglobal production and consumption of food and drink. This project will explore the challenges and potentials that the transformations in production and consumption of food and drink pose to Australia. We have an enviable reputation for our wine and the quality of our food produce. But we have stiff competition from around the world. This is exacerbated by economic and cultural trends, which are changing the face of how and what we eat and drink. The homogenisation of ma ....Taste and Place: the transglobal production and consumption of food and drink. This project will explore the challenges and potentials that the transformations in production and consumption of food and drink pose to Australia. We have an enviable reputation for our wine and the quality of our food produce. But we have stiff competition from around the world. This is exacerbated by economic and cultural trends, which are changing the face of how and what we eat and drink. The homogenisation of mass-market consumption is producing a widespread dissatisfaction with our diet, and obesity. This cross-cultural project will result in important information about how we can best respond to these challenges.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100628
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Promotion of NAD+ anabolism to promote lifespan. The project aims to identify mechanisms of ageing, the role of stress on the ageing brain and how NAD+ modulates these effects. NAD+ maintains cellular energy, repairs DNA and performs other essential cell functions. Intracellular NAD+ levels, the essential substrate for sirtuin activity including SIRT2, decline with age in humans and physiologically aged rats. This project will investigate the mechanisms by which pharmacological strategies design ....Promotion of NAD+ anabolism to promote lifespan. The project aims to identify mechanisms of ageing, the role of stress on the ageing brain and how NAD+ modulates these effects. NAD+ maintains cellular energy, repairs DNA and performs other essential cell functions. Intracellular NAD+ levels, the essential substrate for sirtuin activity including SIRT2, decline with age in humans and physiologically aged rats. This project will investigate the mechanisms by which pharmacological strategies designed to elevate intracellular NAD+ levels will maintain optimal SIRT2 function to extend lifespan and improve age-related cognitive decline in vivo. Potential outcomes include using NAD+ to improve brain health in advanced old age.Read moreRead less
Non-intrusive human activity sensing with radio signals. This project aims to develop a theoretical framework for sensing and detecting human activities based on wireless radio signals. The framework advances the state-of-the-art by discovering the fundamental theory, and defining a set of principles to guide practical system design. The framework will be validated and its scientific merit demonstrated through building several applications such as contactless human activity detection and vital s ....Non-intrusive human activity sensing with radio signals. This project aims to develop a theoretical framework for sensing and detecting human activities based on wireless radio signals. The framework advances the state-of-the-art by discovering the fundamental theory, and defining a set of principles to guide practical system design. The framework will be validated and its scientific merit demonstrated through building several applications such as contactless human activity detection and vital signs monitoring. This should benefit existing hospital and clinical patient services and promote home-care and self-care services at nationwide.Read moreRead less
Towards a model of emotional control: Assessment of patients with focal cortical injuries. This project will produce vital information about a potential mechanism that may underlie the observed association between frontal brain damage and deficits in emotional control. The proposed research will therefore have significant clinical and theoretical implications; it will enable better prediction of emotional dysregulation following brain injury, generation of more accurate models of emotional regul ....Towards a model of emotional control: Assessment of patients with focal cortical injuries. This project will produce vital information about a potential mechanism that may underlie the observed association between frontal brain damage and deficits in emotional control. The proposed research will therefore have significant clinical and theoretical implications; it will enable better prediction of emotional dysregulation following brain injury, generation of more accurate models of emotional regulation, as well as informing the provision and delivery of evidence-based treatments for emotional dysregulation. It will also contribute to our understanding of emotional functioning in other disorders characterized by frontal dysfunction, such as schizophrenia, depression and traumatic brain injury.
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A likelihood-based approach to combined surveys inference. This project focuses on the development of statistical theory for efficient integration of information across multiple complex sample surveys. It will develop theory and methodology that will answer complex questions about relationships between important social, economic and health related variables that are presently measured in separate surveys.