Transdiagnostic Internet Therapy For Internalizing Disorders
Funder
National Health and Medical Research Council
Funding Amount
$687,348.00
Summary
Anxiety and depressive disorders account for 58% of the burden of mental disorders, or 7.5% of the burden of human disease. Internet treatments for the individual disorders are effective but require careful diagnosis. We intend to develop and prove the effectiveness of a transdiagnostic Internet treatment program that will be easily used by primary care clinicians. We will disseminate and evaluate the developed and proven program to general practitioners and psychologists.
Assessment And Prevention Of The Early Signs Of Anxiety And Depression In Children.
Funder
National Health and Medical Research Council
Funding Amount
$149,363.00
Summary
Anxiety and depression are common mental health problems and children rate them as their most common emotional problems. Recent research has indicated that brief psychotherapy programs are effective in reducing these problems in 8 to 14 year olds, however, the earliest signs of these problems are detectable in the preschool years. Thus there is an urgent need for adequately evaluated community prevention programs to address the promotion of sound mental health in much younger children. The aim o ....Anxiety and depression are common mental health problems and children rate them as their most common emotional problems. Recent research has indicated that brief psychotherapy programs are effective in reducing these problems in 8 to 14 year olds, however, the earliest signs of these problems are detectable in the preschool years. Thus there is an urgent need for adequately evaluated community prevention programs to address the promotion of sound mental health in much younger children. The aim of this study is to conduct a comprehensive controlled trial of a community based programme for the detection and prevention of early signs of internalising disorders (i.e., shyness, fears and anxiety, depression). It is hypothesised that by intervening when children are young with the aim of improving parent-child interaction patterns, children will be steered towards a more competent and resilient approach to life. The study consists of three major components. First, we will evaluate the psychometric properties and predictive validity of the best available measures of teachers', parents' and children's' perceptions of the child's adjustment status. Second, we will follow-up the full cohort of preschool children to test which combination of the measures best predicts internalising disorders after 2 years. Third, we will conduct a controlled trial with a sample of the larger cohort to evaluate the effects of a brief parent and teacher training programme on children's adjustment. The major questions of this project are: a) Can we successfully identify children in a community preschool setting and under the age of 6 who are at risk of developing internalizing disorders? b) What assessment measures are the most reliable and valid predictors of the development of internalising disorders in this age group? c) What are the short-term and medium-term effects of a parent and teacher prevention program on children stratified according to risk for internalising disorders?Read moreRead less
Burden Of Disease: Costing An Effective Package Of Care For Mental Disorders
Funder
National Health and Medical Research Council
Funding Amount
$272,735.00
Summary
The Global Burden of Disease project, a WHO-World Bank-Harvard collaboration, presented an unprecedented picture of global health across the developed and developing world, providing much-needed information for planning health services. Health was measured at the population level, and combined the number of life years lost due to death and disablement to give a total amount of life lost per disorder. One surprise of the project was the importance of mental disorders, accounting for 43% of life y ....The Global Burden of Disease project, a WHO-World Bank-Harvard collaboration, presented an unprecedented picture of global health across the developed and developing world, providing much-needed information for planning health services. Health was measured at the population level, and combined the number of life years lost due to death and disablement to give a total amount of life lost per disorder. One surprise of the project was the importance of mental disorders, accounting for 43% of life years lost due to disability in countries like Australia. Service planning to reduce this burden requires knowledge of cost-effective treatments.This project will trial a method used for combining burden and cost-effectiveness data to design an essential package of services to address the treatment shortfall in mental disorders. This research will assist in our understanding of why burden due to mental disorders persists, and the extent to which current treatment knowledge is able to address this burden within existing budgetary constraints. This will be achieved by: 1) detailing the costs and population outcome of current services in Australia for mental disorders, to determine which disorders are currently adequately treated and which disorders require further intervention, 2) calculating the costs and outcome of best practice interventions from clinical practice guidelines, to understand the extent to which current treatment knowledge can reduce burden due to mental disorders, 3) examining the equity consequences of such a package of ideal interventions, with the understanding that the treatment endpoint is not the same for all disorders. This is a secondary analysis, representing a method for translating existing cost and outcome data for individual treatments into their costs and consequences for health planning at the population level.Read moreRead less
Balance disorders are very common, but particularly in those conditions that involve the brain 'balance centres' are often difficult for doctors to diagnose. When diseases are difficult to diagnose, then recommending helpful treatment is particularly challenging. We will use a group of specialized tests to better understand these balance conditions in order to help patients receive accurate diagnoses and therefore, better treatment.
Balance disorders are very common, but particularly in those conditions that involve the brain 'balance centres' are often difficult for doctors to diagnose. When diseases are difficult to diagnose, then recommending helpful treatment is particularly challenging. We will use a group of specialized tests to better understand these balance conditions in order to help patients receive accurate diagnoses and therefore, better treatment.
Molecular Mediators, Epigenetic Modulators And Therapeutic Targets For Cognitive Disorders
Funder
National Health and Medical Research Council
Funding Amount
$763,845.00
Summary
Brain disorders constitute an enormous, and growing, burden. My research investigates how genes and environment combine to cause disorders of cognition, including dementia, schizophrenia and autism. The research will provide new insights into these disorders, at the level of molecules, cells and behaviour. I will explore how genetic and environmental factors interact, with a focus on mental activity, physical exercise and stress, which affect a range of neurological and psychiatric disorders.
Ocular Motility In Autism And Asperger S Disorder: Dissociation Of Motor Deficits.
Funder
National Health and Medical Research Council
Funding Amount
$131,235.00
Summary
We will use ocular motor technology to investigate motor dysfunction in autism and Asperger's disorder, to advance our understanding of the neurobiological bases of these disorders. This will help clarify whether neural networks are differentially disrupted in these disorders, as our previous clinical research suggests. This dissociation and the subsequent development of an ocular motor clincal screen may improve diagnosis, and potentially treatment, of these devastating conditions.