MicroRNA Dysregulation As A Mechanism Underlying Muscle Wasting
Funder
National Health and Medical Research Council
Funding Amount
$514,454.00
Summary
Frailty caused by muscle wasting shortens many peoples' lives and costs hundreds of billions of dollars in care and lost productivity annually. In the hope of finding ways to treat frailty, we will study whether naturally-occurring microRNA molecules are responsible for disrupting gene expression to cause muscle disease. We will identify which types of microRNA are altered in muscle diseases, and test whether adjusting microRNA levels with new approaches can prevent-treat muscle wasting.